Methotrexate and Leukoencephalopathy - from FDA reports
Leukoencephalopathy is found among people who take Methotrexate, especially for people who are female, 10-19 old , have been taking the drug for < 1 month, also take medication Cytarabine, and have Acute lymphocytic leukemia (all). This review analyzes which people have Leukoencephalopathy with Methotrexate. It is created by eHealthMe based on reports of 231,270 people who have side effects when taking Methotrexate from FDA , and is updated regularly.
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On Jul, 23, 2017
231,270 people reported to have side effects when taking Methotrexate.
Among them, 506 people (0.22%) have Leukoencephalopathy
Number of reports submitted per year:
Time on Methotrexate when people have Leukoencephalopathy *:
- < 1 month: 64.65 %
- 1 - 6 months: 23.23 %
- 6 - 12 months: 6.06 %
- 1 - 2 years: 3.03 %
- 2 - 5 years: 1.01 %
- 5 - 10 years: 0.0 %
- 10+ years: 2.02 %
Gender of people who have Leukoencephalopathy when taking Methotrexate *:
- female: 60.45 %
- male: 39.55 %
Age of people who have Leukoencephalopathy when taking Methotrexate *:
- 0-1: 0.49 %
- 2-9: 20.34 %
- 10-19: 38.24 %
- 20-29: 2.7 %
- 30-39: 5.88 %
- 40-49: 5.15 %
- 50-59: 11.52 %
- 60+: 15.69 %
Top conditions involved for these people *:
- Acute Lymphocytic Leukemia (all) (140 people, 27.67%)
- Non-Hodgkin's Lymphoma (26 people, 5.14%)
- Central Nervous System Lymphoma (20 people, 3.95%)
- Preventive Health Care (18 people, 3.56%)
- Lymphoma (17 people, 3.36%)
Top co-used drugs for these people *:
- Cytarabine (146 people, 28.85%)
- Cyclophosphamide (84 people, 16.60%)
- Etoposide (73 people, 14.43%)
- Prednisone (48 people, 9.49%)
- Mercaptopurine (44 people, 8.70%)
Top other side effects for these people *:
- Speech Impairment (adult) (62 people, 12.25%)
- Weakness (52 people, 10.28%)
- Neurotoxicity (47 people, 9.29%)
- Headache (37 people, 7.31%)
- Convulsion (36 people, 7.11%)
* Approximation only. Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Do you have Leukoencephalopathy when taking Methotrexate?
Expand the study to include all drugs with the same ingredientsLeukoencephalopathy and drugs with ingredients of methotrexate sodium.
Expand the study to include reports from both FDA and eHealthMeLeukoencephalopathy and Methotrexate from FDA and eHealthMe reports
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 234,868 users)
Leukoencephalopathy (disease of the white matter in the brain) has been reported by people with acute lymphocytic leukemia (all), rheumatoid arthritis, high blood pressure, multiple myeloma, pain (latest reports from 2,596 Leukoencephalopathy patients).
Browse all side effects of Methotrexatea b c d e f g h i j k l m n o p q r s t u v w x y z
Drugs that are associated with LeukoencephalopathyLeukoencephalopathy
Could your condition cause LeukoencephalopathyLeukoencephalopathy
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I started a low dose (10 mg) of methotrexate for rheumatoid arthritis last week and noticed this week, after taking my second does, that my face is breaking out. Does anyone have any similar experiences? I also take 5 mg of folic acid daily. Thanks for any help you can offer up.
Not sure what where to go with this. I have fibromyalgia and relapsing polchondritus also a disability from va.. I have my flares mostly under control. As well as what to do when they become apparent. After many years on pharmaceuticals I went a different direction. With medical marijauna. ...
Hi there, My names Adele I am 41 and have RA. I had my Gall Bladder removed in March of this year due to stones and constant infections. 2 years ago I stopped taking MTX subcutaneous and unfortunately my RA has progressed to a point I have (today) re-started these. I have headache, nausea and ...
Several years ago in 2013 I was"diagnosed" with RA. I went through every medication including, humira, embral, to now IV fusions of remicade which has been almost a year. I am not feeling any better and body aches and joint pains getting worse. I started researching my symptoms and lyme kept ...
This is for my father. Shortly after starting methotrexate injections and cortisone for Rheumatoid arthritis my father started having language difficulties and now has dementia. He was diagnosed with Pick's disease. Could it be caused by these drugs? He is still taking them.
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