Review: could Methotrexate cause Lyme Disease?


Summary

Lyme disease is found among people who take Methotrexate, especially for people who are male, 40-49 old , have been taking the drug for 10+ years, also take medication Humira, and have Rheumatoid arthritis . We study 128,586 people who have side effects while taking Methotrexate from FDA and social media. Among them, 25 have Lyme disease. Find out below who they are, when they have Lyme disease and more.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 129,243 users)

Lyme Disease

Lyme disease (a bacterial infection that is spread to humans by infected ticks) has been reported by people with paraesthesia, pain, breathing difficulty, weakness, diarrhea (latest reports from 1,529 Lyme disease patients).

On Jul, 24, 2016

128,586 people reported to have side effects when taking Methotrexate.
Among them, 25 people (0.02%) have Lyme Disease


Number of reports submitted per year:

Could Methotrexate cause Lyme disease?

Time on Methotrexate when people have Lyme Disease *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

Gender of people who have Lyme Disease when taking Methotrexate *:

  • female: 41.67 %
  • male: 58.33 %

Age of people who have Lyme Disease when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 26.32 %
  • 20-29: 5.26 %
  • 30-39: 0.0 %
  • 40-49: 36.84 %
  • 50-59: 21.05 %
  • 60+: 10.53 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (12 people)
  • Crohn's Disease (5 people)
  • Leukaemia (2 people)
  • Acute Leukaemia (2 people)
  • Hypersensitivity (1 person)

Top co-used drugs for these people *:

  • Humira (7 people)
  • Folic Acid (6 people)
  • Enbrel (6 people)
  • Remicade (4 people)
  • Prednisolone (4 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Lyme disease when taking Methotrexate?


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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