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Review: could Methotrexate cause Lymphedema?

Summary: Lymphedema could be caused by Methotrexate, especially for people who are female, 50-59 old, also take Aas infantil, and have Rheumatoid arthritis.

We study 129,658 people who have side effects while taking Methotrexate from FDA and social media. Among them, 7 have Lymphedema. Find out below who they are, when they have Lymphedema and more.

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Methotrexate

Methotrexate (latest outcomes from 130,985 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Lymphedema

Lymphedema (a condition of localized fluid retention and tissue swelling of lymph node) (latest reports from 411 patients) has been reported by people with rheumatoid arthritis, high blood pressure, hiv infection, birth control, weight loss.

On Apr, 10, 2014: 129,615 people reported to have side effects when taking Methotrexate. Among them, 7 people (0.01%) have Lymphedema. They amount to 1.71% of all the 410 people who have Lymphedema on eHealthMe.

Trend of Lymphedema in Methotrexate reports

Time on Methotrexate when people have Lymphedema * :

n/a

Gender of people who have Lymphedema when taking Methotrexate * :

FemaleMale
Lymphedema100.00%0.00%

Age of people who have Lymphedema when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Lymphedema0.00%0.00%0.00%0.00%0.00%0.00%100.00%0.00%

Severity of Lymphedema when taking Methotrexate ** :

n/a

How people recovered from Lymphedema ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (7 people, 100.00%)

Top co-used drugs for these people * :

  1. Aas infantil (7 people, 100.00%)
  2. Prednisone (7 people, 100.00%)
  3. Ibuprofen (7 people, 100.00%)
  4. Arava (7 people, 100.00%)
  5. Selozok (6 people, 85.71%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Methotrexate, Lymphedema

You can also:

On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 days ago):

  • my chest hurts so bad from coughing i cant take the pain. the coughing is so severe it causes me to lose control of my bladder. i have an awful headache from coughing so loud and so severe. i have been in bed for nearly a month I am so sick. i can hear my lungs breathing with my mouth closed it sounds so strange to hear my lungs making crackling noises outside of my chest.

    Reply

  • From this study (2 days ago):

  • Sarcoidosis caused complete heart block. Pacemaker implanted in December 2009 but for the past two years I have had palpitations caused by around 3.7 million ectopic heartbeats per year.

    Sarcoidosis also in lungs and eyes. Extended use of Pred Forte caused development of cataracts, one of which has been removed and I am awaiting the second operation.

    Breathlessness is caused by lack of oxygen entering the bloodstream and my ongoing heart problems

    Rarely able to sleep properly due to pain, sleeping for about 20 minutes at a time when I become so exhausted that the pain can't keep me awake

    Muscle and joint pain have made me weak and clumsy.Pain is felt all over, from head to toes along with muscle cramps and intense burning sensation to skin on lower legs.

    ACE levels fluctuate but average 110 - 150.

    Blood pressure on average is 150 / 78 - no treatment given

    I also take Nefopam Hydrochloride (Acupan) for pain but this drug is not on the list.

    Immobility, fatigue and constant pain have left me very depressed ad harbouring thoughts of suicide. My 15 year old granddaughter has lived with me since the death of my daughter 11 years ago and it is my hope that I will live long enough to see her settled in college and independent after which the only thing I have to look forward to is to end my own suffering.

    Reply

  • From this study (4 days ago):

  • Trying to determine if the timing of these drugs- especially the weekly mtx- should be staggered during the day to ensure they are appropriately absorbed. Periodic seizures continue- about once a quarter.

    Reply

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