Methotrexate and Lymphoma - from FDA reports


Summary

Lymphoma is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 5 - 10 years, also take medication Remicade, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 755 have Lymphoma. Find out below who they are, when they have Lymphoma and more.

What to expect?

If you take Methotrexate and have Lymphoma, find out what symptoms you could have in 1 year or longer.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,560 users)

Lymphoma

Lymphoma (cancer that begins in immune system cells) has been reported by people with rheumatoid arthritis, lymphoma, multiple sclerosis, crohn's disease, high blood pressure (latest reports from 15,451 Lymphoma patients).

On Feb, 01, 2017

209,150 people reported to have side effects when taking Methotrexate.
Among them, 755 people (0.36%) have Lymphoma


Number of reports submitted per year:

Could Methotrexate cause Lymphoma?

Time on Methotrexate when people have Lymphoma *:

  • < 1 month: 15.45 %
  • 1 - 6 months: 17.07 %
  • 6 - 12 months: 4.07 %
  • 1 - 2 years: 9.76 %
  • 2 - 5 years: 22.76 %
  • 5 - 10 years: 22.76 %
  • 10+ years: 8.13 %

Gender of people who have Lymphoma when taking Methotrexate *:

  • female: 68.83 %
  • male: 31.17 %

Age of people who have Lymphoma when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 1.13 %
  • 10-19: 2.46 %
  • 20-29: 2.46 %
  • 30-39: 4.73 %
  • 40-49: 8.88 %
  • 50-59: 20.98 %
  • 60+: 59.36 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (500 people, 66.23%)
  • Psoriatic Arthropathy (45 people, 5.96%)
  • High Blood Pressure (36 people, 4.77%)
  • Preventive Health Care (27 people, 3.58%)
  • Pain (27 people, 3.58%)

Top co-used drugs for these people *:

  • Remicade (236 people, 31.26%)
  • Folic Acid (149 people, 19.74%)
  • Enbrel (147 people, 19.47%)
  • Humira (116 people, 15.36%)
  • Prednisone (100 people, 13.25%)

Top other side effects for these people *:

  • Lymph Follicular Hypertrophy (63 people, 8.34%)
  • Fever (42 people, 5.56%)
  • Pneumonia (35 people, 4.64%)
  • Pancytopenia (33 people, 4.37%)
  • Joint Pain (32 people, 4.24%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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