Could Methotrexate cause Lymphoma - from FDA reports
Lymphoma is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 5 - 10 years, also take medication Remicade, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 755 have Lymphoma. Find out below who they are, when they have Lymphoma and more.
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Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,527 users)
Lymphoma (cancer that begins in immune system cells) has been reported by people with rheumatoid arthritis, lymphoma, multiple sclerosis, crohn's disease, high blood pressure (latest reports from 15,451 Lymphoma patients).
On Dec, 30, 2016
209,150 people reported to have side effects when taking Methotrexate.
Among them, 755 people (0.36%) have Lymphoma
Number of reports submitted per year:
Time on Methotrexate when people have Lymphoma *:
- < 1 month: 15.45 %
- 1 - 6 months: 17.07 %
- 6 - 12 months: 4.07 %
- 1 - 2 years: 9.76 %
- 2 - 5 years: 22.76 %
- 5 - 10 years: 22.76 %
- 10+ years: 8.13 %
Gender of people who have Lymphoma when taking Methotrexate *:
- female: 68.83 %
- male: 31.17 %
Age of people who have Lymphoma when taking Methotrexate *:
- 0-1: 0.0 %
- 2-9: 1.13 %
- 10-19: 2.46 %
- 20-29: 2.46 %
- 30-39: 4.73 %
- 40-49: 8.88 %
- 50-59: 20.98 %
- 60+: 59.36 %
Top conditions involved for these people *:
- Rheumatoid Arthritis (500 people, 66.23%)
- Psoriatic Arthropathy (45 people, 5.96%)
- High Blood Pressure (36 people, 4.77%)
- Preventive Health Care (27 people, 3.58%)
- Pain (27 people, 3.58%)
Top co-used drugs for these people *:
- Remicade (236 people, 31.26%)
- Folic Acid (149 people, 19.74%)
- Enbrel (147 people, 19.47%)
- Humira (116 people, 15.36%)
- Prednisone (100 people, 13.25%)
Top other side effects for these people *:
- Lymph Follicular Hypertrophy (63 people, 8.34%)
- Fever (42 people, 5.56%)
- Pneumonia (35 people, 4.64%)
- Pancytopenia (33 people, 4.37%)
- Joint Pain (32 people, 4.24%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Can you answer these questions?
I started a low dose (10 mg) of methotrexate for rheumatoid arthritis last week and noticed this week, after taking my second does, that my face is breaking out. Does anyone have any similar experiences? I also take 5 mg of folic acid daily. Thanks for any help you can offer up.
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Hi there, My names Adele I am 41 and have RA. I had my Gall Bladder removed in March of this year due to stones and constant infections. 2 years ago I stopped taking MTX subcutaneous and unfortunately my RA has progressed to a point I have (today) re-started these. I have headache, nausea and ...
Several years ago in 2013 I was"diagnosed" with RA. I went through every medication including, humira, embral, to now IV fusions of remicade which has been almost a year. I am not feeling any better and body aches and joint pains getting worse. I started researching my symptoms and lyme kept ...
This is for my father. Shortly after starting methotrexate injections and cortisone for Rheumatoid arthritis my father started having language difficulties and now has dementia. He was diagnosed with Pick's disease. Could it be caused by these drugs? He is still taking them.
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My RA is mild. The methotrexate caused my cholesterol to rise. The Lipitor caused my blood sugar to rise. The rheumatologist denied that the Methotrexate did this but I found research by peer reviewed journals that reported this finding.
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