Methotrexate and Memory loss - from FDA reports


Summary

Memory loss is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 1,473 have Memory loss. Find out below who they are, when they have Memory loss and more.

What to expect?

If you take Methotrexate and have Memory loss, find out what symptoms you could have in 1 year or longer.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,560 users)

Memory Loss

Memory loss has been reported by people with multiple sclerosis, depression, pain, high blood pressure, high blood cholesterol (latest reports from 105,190 Memory loss patients).

On Feb, 21, 2017

209,150 people reported to have side effects when taking Methotrexate.
Among them, 1,473 people (0.7%) have Memory Loss


Number of reports submitted per year:

Could Methotrexate cause Memory loss?

Time on Methotrexate when people have Memory Loss *:

  • < 1 month: 24.07 %
  • 1 - 6 months: 24.07 %
  • 6 - 12 months: 7.41 %
  • 1 - 2 years: 7.41 %
  • 2 - 5 years: 13.89 %
  • 5 - 10 years: 18.52 %
  • 10+ years: 4.63 %

Gender of people who have Memory Loss when taking Methotrexate *:

  • female: 78.46 %
  • male: 21.54 %

Age of people who have Memory Loss when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 1.11 %
  • 10-19: 3.93 %
  • 20-29: 3.5 %
  • 30-39: 4.7 %
  • 40-49: 16.31 %
  • 50-59: 27.67 %
  • 60+: 42.78 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (802 people, 54.45%)
  • High Blood Pressure (128 people, 8.69%)
  • Psoriatic Arthropathy (109 people, 7.40%)
  • Pain (96 people, 6.52%)
  • Depression (88 people, 5.97%)

Top co-used drugs for these people *:

  • Enbrel (401 people, 27.22%)
  • Humira (317 people, 21.52%)
  • Folic Acid (317 people, 21.52%)
  • Prednisone (175 people, 11.88%)
  • Remicade (157 people, 10.66%)

Top other side effects for these people *:

  • Fatigue (264 people, 17.92%)
  • Joint Pain (233 people, 15.82%)
  • Headache (232 people, 15.75%)
  • Pain (229 people, 15.55%)
  • Nausea (186 people, 12.63%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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