Review: could Methotrexate cause Memory Loss?


Summary

Memory loss is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Folic Acid, and have Rheumatoid arthritis . We study 150,777 people who have side effects while taking Methotrexate from FDA and social media. Among them, 934 have Memory loss. Find out below who they are, when they have Memory loss and more.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 152,717 users)

Memory Loss

Memory loss has been reported by people with drowsiness, drug ineffective, diarrhea, fall, insomnia (latest reports from 71,070 Memory loss patients).

On Aug, 23, 2016

150,777 people reported to have side effects when taking Methotrexate.
Among them, 934 people (0.62%) have Memory Loss


Number of reports submitted per year:

Could Methotrexate cause Memory loss?

Time on Methotrexate when people have Memory Loss *:

  • < 1 month: 23.96 %
  • 1 - 6 months: 17.71 %
  • 6 - 12 months: 11.46 %
  • 1 - 2 years: 6.25 %
  • 2 - 5 years: 15.62 %
  • 5 - 10 years: 18.75 %
  • 10+ years: 6.25 %

Gender of people who have Memory Loss when taking Methotrexate *:

  • female: 76.15 %
  • male: 23.85 %

Age of people who have Memory Loss when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 1.34 %
  • 10-19: 4.7 %
  • 20-29: 2.68 %
  • 30-39: 5.37 %
  • 40-49: 20.13 %
  • 50-59: 26.58 %
  • 60+: 39.19 %

Severity if Memory Loss when taking Methotrexate **:

  • least: 11.11 %
  • moderate: 61.11 %
  • severe: 22.22 %
  • most severe: 5.56 %

How people recovered from Memory Loss **:

  • while on drug: 12.5 %
  • after off the drug: 0.0 %
  • not yet: 87.5 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (475 people)
  • Hypertension (73 people)
  • Psoriatic Arthropathy (63 people)
  • Pain (58 people)
  • Depression (56 people)

Top co-used drugs for these people *:

  • Folic Acid (298 people)
  • Enbrel (218 people)
  • Humira (199 people)
  • Prednisone (164 people)
  • Remicade (126 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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