Methotrexate and Mood swings - from FDA reports


Summary

Mood swings is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Humira, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 258 have Mood swings. Find out below who they are, when they have Mood swings and more.

What to expect?

If you take Methotrexate and have Mood swings, find out what symptoms you could have in 1 year or longer.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,557 users)

Mood Swings

Mood swings (an extreme or rapid change in mood) has been reported by people with depression, birth control, quit smoking, pain (latest reports from 39,398 Mood swings patients).

On Feb, 18, 2017

209,150 people reported to have side effects when taking Methotrexate.
Among them, 258 people (0.12%) have Mood Swings


Number of reports submitted per year:

Could Methotrexate cause Mood swings?

Time on Methotrexate when people have Mood Swings *:

  • < 1 month: 30.77 %
  • 1 - 6 months: 7.69 %
  • 6 - 12 months: 7.69 %
  • 1 - 2 years: 30.77 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 23.08 %
  • 10+ years: 0.0 %

Gender of people who have Mood Swings when taking Methotrexate *:

  • female: 69.92 %
  • male: 30.08 %

Age of people who have Mood Swings when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 4.02 %
  • 10-19: 10.05 %
  • 20-29: 12.06 %
  • 30-39: 5.53 %
  • 40-49: 14.07 %
  • 50-59: 23.12 %
  • 60+: 31.16 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (104 people, 40.31%)
  • Psoriatic Arthropathy (20 people, 7.75%)
  • Pain (15 people, 5.81%)
  • Crohn's Disease (15 people, 5.81%)
  • Sleep Disorder (13 people, 5.04%)

Top co-used drugs for these people *:

  • Humira (78 people, 30.23%)
  • Enbrel (70 people, 27.13%)
  • Folic Acid (54 people, 20.93%)
  • Prednisone (25 people, 9.69%)
  • Remicade (23 people, 8.91%)

Top other side effects for these people *:

  • Fatigue (61 people, 23.64%)
  • Headache (56 people, 21.71%)
  • Nausea (50 people, 19.38%)
  • Depression (49 people, 18.99%)
  • Joint Pain (48 people, 18.60%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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