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Review: could Methotrexate cause Mood swings?





Summary: Mood swings is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Folic acid, and have Rheumatoid arthritis.

We study 129,858 people who have side effects while taking Methotrexate from FDA and social media. Among them, 111 have Mood swings. Find out below who they are, when they have Mood swings and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Mood swings >>>

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 131,201 users)

Mood swings

Mood swings (an extreme or rapid change in mood) has been reported by people with quit smoking, depression, birth control, attention deficit hyperactivity disorder, stress and anxiety.(latest reports from Mood swings 24,705 patients)

On Dec, 13, 2014: 129,841 people reported to have side effects when taking Methotrexate. Among them, 111 people (0.09%) have Mood Swings.

Trend of Mood swings in Methotrexate reports

Time on Methotrexate when people have Mood swings * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Mood swings0.00%62.50%0.00%12.50%0.00%12.50%12.50%

Gender of people who have Mood swings when taking Methotrexate * :

FemaleMale
Mood swings69.60%30.40%

Age of people who have Mood swings when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Mood swings0.00%4.63%20.37%5.56%4.63%8.33%24.07%32.41%

Severity of Mood swings when taking Methotrexate ** :

leastmoderateseveremost severe
Mood swings0.00%75.00%25.00%0.00%

How people recovered from Mood swings ** :

while on the drugafter off the drugnot yet
Mood swings50.00%0.00%50.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (44 people, 39.64%)
  2. Crohn's disease (11 people, 9.91%)
  3. Anxiety (9 people, 8.11%)
  4. Pain (8 people, 7.21%)
  5. Arthritis (8 people, 7.21%)

Top co-used drugs for these people * :

  1. Folic acid (45 people, 40.54%)
  2. Humira (38 people, 34.23%)
  3. Enbrel (24 people, 21.62%)
  4. Prednisone (17 people, 15.32%)
  5. Methotrexate sodium (15 people, 13.51%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Mood Swings while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Mood Swings
- support group for people who take Methotrexate
- support group for people who have Mood Swings

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More questions for: Methotrexate, Mood swings

You may be interested at these reviews (Write a review):

  • Humira: my experience
    (Posted by a 66 year old man who has Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, and takes Methotrexate Preservative Free, Enbrel, Humira)
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long. I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, ...
  • Lo loestrin and breast plate pain
    (Posted by a 33 year old man who has Severe Acne And Facial Cysts, Mood Swings, Costochondritis, and takes Lo Loestrin Fe)
    This has to be the worst birth control I have ever taken. I felt like two different people. I turned into a lunatic when I was in my cycle - which I never knew when I was on my cycle because I bled for two days here, four days there, 5 days another time. I never knew when I was going to bleed. My fa ...
  • Psoratic arthritis and trigeminal neuralgia
    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...
  • Spiriva caused me to swell up like a hippo.
    (Posted by a 46 year old woman who has Rheumatoid Arthritis, Irritable Bowel Syndrome, and takes Advair Diskus 250/50, Methotrexate, Plaquenil, Metformin, Klonopin, Zanaflex, Prednisone, Singulair, Imitrex, Nexium)
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...
  • Personalized review of arava (1 response)
    (Posted by a 65 year old woman who has Rheumatoid Arthritis, and takes Methotrexate)
    Have had RA for 10 years and was on Methotrexate those 10 years. Had nose bleeds which got progressively worse over the years and began to effect my quality of living. Doctor said it could NOT be the drug, but according to eHealth Me, it could. At urging of an ENT, I stopped taking Methotrexate ...

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