Review: could Methotrexate cause Mood swings?
Summary: Mood swings is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Folic acid, and have Rheumatoid arthritis.
We study 129,908 people who have side effects while taking Methotrexate from FDA and social media. Among them, 112 have Mood swings. Find out below who they are, when they have Mood swings and more.
You are not alone: join a support group for people who take Methotrexate and have Mood swings >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,250 Methotrexate users)
Mood swings (an extreme or rapid change in mood) has been reported by people with quit smoking, depression, birth control, attention deficit hyperactivity disorder, stress and anxiety. (latest reports from 24,771 Mood swings patients)
On Mar, 16, 2015: 129,897 people reported to have side effects when taking Methotrexate. Among them, 112 people (0.09%) have Mood Swings.
Time on Methotrexate when people have Mood swings * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Mood swings||0.00%||55.56%||0.00%||11.11%||11.11%||11.11%||11.11% |
Gender of people who have Mood swings when taking Methotrexate * :
|Mood swings||69.84%||30.16% |
Age of people who have Mood swings when taking Methotrexate * :
|Mood swings||0.00%||4.59%||20.18%||5.50%||4.59%||9.17%||23.85%||32.11% |
Severity of Mood swings when taking Methotrexate ** :
|least||moderate||severe||most severe |
|Mood swings||0.00%||80.00%||20.00%||0.00% |
How people recovered from Mood swings ** :
|while on the drug||after off the drug||not yet |
|Mood swings||50.00%||0.00%||50.00% |
Top conditions involved for these people * :
- Rheumatoid arthritis (44 people, 39.29%)
- Crohn's disease (11 people, 9.82%)
- Anxiety (9 people, 8.04%)
- Pain (8 people, 7.14%)
- Arthritis (8 people, 7.14%)
Top co-used drugs for these people * :
- Folic acid (45 people, 40.18%)
- Humira (38 people, 33.93%)
- Enbrel (24 people, 21.43%)
- Prednisone (17 people, 15.18%)
- Methotrexate sodium (15 people, 13.39%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Get connected: join our support group of methotrexate and mood swings on
Do you have Mood Swings while taking Methotrexate?
You are not alone! Join a mobile support group on :
- support group for people who take Methotrexate and have Mood Swings
- support group for people who take Methotrexate
- support group for people who have Mood Swings
Drugs in real world that are associated with:
Could your condition cause:
- A study of drug interactions between Prednisolone, Plaquenil, Leflunomide, Methotrexate for a 63-year old woman with Rheumatoid Arthritis. The patient has Folliculitis
- A study of drug interactions between Folic Acid, Vitamin D, Zoloft, Methotrexate, Plaquenil for a 53-year old woman with Hair Loss, Iga Deficiency, Depression, Rheumatoid Arthritis, Lupus Erythematosus. The patient has Don't Want To Socialize At All
- A study of side effects of Vyvanse for a 47-year old woman with ADD. The patient has Mood Swings (an extreme or rapid change in mood)
- A study of side effects of Levothyroxine Sodium for a 28-year old woman with Hypothyroidism. The patient has Change In Appetite, Mood Swings (an extreme or rapid change in mood), Change In Mentrual Cycle, Headache (pain in head), Fatigue (feeling of tiredness), Anxiety
- A study of drug interactions between Trazodone Hydrochloride, Clonazepam, Gabapentin for a 26-year old man with Initial Insomnia, Anxiety And Stress, Anxiety Disorder. The patient has Heart Palpitations, Chest Pain, Confusion, Fear, Irritability, Mood Swings, Paranoia, Electric Shock
Recent Methotrexate related drug comparison:
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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