Review: could Methotrexate cause Mood swings?
(By eHealthMe on Mar, 9, 2014)
Severity ratings: 2.5/4
On a scale of 1 to 4: 1=least, 2=moderate, 3=severe, 4=most severe
We study 124,856 people who take Methotrexate. Among them, 109 have Mood swings. See who they are, when they have Mood swings and more. This review is based on reports from FDA and social media, and is updated regularly.
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Methotrexate (latest outcomes from 130,928 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis, psoriatic arthritis. Commonly reported side effects of Methotrexate include fever, injection site pain, joint pain, nausea, nausea aggravated.
Mood swings (an extreme or rapid change in mood) (latest reports from 117,606 patients) has been reported by people with quit smoking, depression, birth control, attention deficit hyperactivity disorder, pain.
On Mar, 9, 2014: 124,856 people reported to have side effects when taking Methotrexate. Among them, 109 people (0.09%) have Mood Swings. They amount to 0.09% of all the 117,442 people who have Mood Swings.
Time on Methotrexate when people have Mood swings * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Mood swings||0.00%||66.67%||0.00%||16.67%||0.00%||16.67%||0.00% |
Gender of people who have Mood swings when taking Methotrexate * :
|Mood swings||69.11%||30.89% |
Age of people who have Mood swings when taking Methotrexate * :
|Mood swings||0.00%||4.72%||19.81%||5.66%||4.72%||7.55%||24.53%||33.02% |
Severity of Mood swings when taking Methotrexate ** :
|least||moderate||severe||most severe |
|Mood swings||0.00%||50.00%||50.00%||0.00% |
How people recovered from Mood swings ** :
Top conditions involved for these people * :
- Rheumatoid arthritis (43 people, 39.45%)
- Crohn's disease (11 people, 10.09%)
- Anxiety (9 people, 8.26%)
- Arthritis (8 people, 7.34%)
- Blood cholesterol (8 people, 7.34%)
Top co-used drugs for these people * :
- Folic acid (44 people, 40.37%)
- Humira (37 people, 33.94%)
- Enbrel (23 people, 21.10%)
- Prednisone (16 people, 14.68%)
- Methotrexate sodium (15 people, 13.76%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
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Related topic: Methotrexate, Mood swings
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On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
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From this study (2 years ago):
Heidi on Jun, 17, 2012:
I was on Methotrexate injections for a year & then went off of it for about five months. I've been back on it now for 3 weeks now. My family & friends have all noticed (as well as myself) that I have been irritable, moody, mean & edgy since restarting my Methotrexate treatment. I also am always tired while I am taking the drug. I feel as though I can't get enough sleep to feel refreshed & rested. The mood swings are really getting to me. I am actually contemplating stopping the medication for good due to the mood swings it is causing me. I am even on Prozac for depression/anxiety. I can't imagine how bad I would feel if I weren't taking that as well.
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