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Review: could Methotrexate cause Nodule?





Summary: Nodule is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Humira, and have Rheumatoid arthritis.

We study 129,858 people who have side effects while taking Methotrexate from FDA and social media. Among them, 251 have Nodule. Find out below who they are, when they have Nodule and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Nodule >>>

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)

Nodule

Nodule (a small rock or mineral cluster) has been reported by people with rheumatoid arthritis, osteoporosis, high blood pressure, pain, osteopenia.(latest reports from Nodule 2,820 patients)

On Nov, 26, 2014: 129,841 people reported to have side effects when taking Methotrexate. Among them, 251 people (0.19%) have Nodule.

Trend of Nodule in Methotrexate reports

Time on Methotrexate when people have Nodule * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Nodule10.53%36.84%10.53%0.00%15.79%10.53%15.79%

Gender of people who have Nodule when taking Methotrexate * :

FemaleMale
Nodule74.45%25.55%

Age of people who have Nodule when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Nodule0.00%1.78%4.00%2.22%2.67%15.56%24.44%49.33%

Severity of Nodule when taking Methotrexate ** :

n/a

How people recovered from Nodule ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (190 people, 75.70%)
  2. Pain (49 people, 19.52%)
  3. Hypertension (35 people, 13.94%)
  4. Osteoporosis (21 people, 8.37%)
  5. Psoriatic arthropathy (21 people, 8.37%)

Top co-used drugs for these people * :

  1. Humira (102 people, 40.64%)
  2. Folic acid (79 people, 31.47%)
  3. Enbrel (70 people, 27.89%)
  4. Prednisone (64 people, 25.50%)
  5. Remicade (33 people, 13.15%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Nodule while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Nodule
- support group for people who take Methotrexate
- support group for people who have Nodule

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More questions for: Methotrexate, Nodule

You may be interested at these reviews (Write a review):

  • Humira: my experience
    (Posted by a 66 year old man who has Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, and takes Methotrexate Preservative Free, Enbrel, Humira)
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long. I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, ...
  • Psoratic arthritis and trigeminal neuralgia
    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...
  • Spiriva caused me to swell up like a hippo.
    (Posted by a 46 year old woman who has Rheumatoid Arthritis, Irritable Bowel Syndrome, and takes Advair Diskus 250/50, Methotrexate, Plaquenil, Metformin, Klonopin, Zanaflex, Prednisone, Singulair, Imitrex, Nexium)
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...
  • Personalized review of arava (1 response)
    (Posted by a 65 year old woman who has Rheumatoid Arthritis, and takes Methotrexate)
    Have had RA for 10 years and was on Methotrexate those 10 years. Had nose bleeds which got progressively worse over the years and began to effect my quality of living. Doctor said it could NOT be the drug, but according to eHealth Me, it could. At urging of an ENT, I stopped taking Methotrexate ...

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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