Could Methotrexate cause Nodule - from FDA reports


Summary

Nodule is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis . We study 197,034 people who have side effects while taking Methotrexate from FDA. Among them, 610 have Nodule. Find out below who they are, when they have Nodule and more.

What to expect?

Forecast new symptoms or undetected conditions when you take Methotrexate and have Nodule

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,501 users)

Nodule

Nodule (a small rock or mineral cluster) has been reported by people with rheumatoid arthritis, osteoporosis, high blood pressure, pain, psoriasis (latest reports from 5,786 Nodule patients).

On Nov, 24, 2016

197,034 people reported to have side effects when taking Methotrexate.
Among them, 610 people (0.31%) have Nodule


Number of reports submitted per year:

Could Methotrexate cause Nodule?

Time on Methotrexate when people have Nodule *:

  • < 1 month: 29.17 %
  • 1 - 6 months: 14.58 %
  • 6 - 12 months: 6.25 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 10.42 %
  • 5 - 10 years: 14.58 %
  • 10+ years: 8.33 %

Gender of people who have Nodule when taking Methotrexate *:

  • female: 78.9 %
  • male: 21.1 %

Age of people who have Nodule when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.8 %
  • 10-19: 1.4 %
  • 20-29: 2.2 %
  • 30-39: 3.59 %
  • 40-49: 16.97 %
  • 50-59: 32.53 %
  • 60+: 42.51 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (443 people, 72.62%)
  • Pain (63 people, 10.33%)
  • High Blood Pressure (52 people, 8.52%)
  • Psoriatic Arthropathy (45 people, 7.38%)
  • High Blood Cholesterol (28 people, 4.59%)

Top co-used drugs for these people *:

  • Enbrel (258 people, 42.30%)
  • Humira (174 people, 28.52%)
  • Folic Acid (125 people, 20.49%)
  • Prednisone (91 people, 14.92%)
  • Omeprazole (38 people, 6.23%)

Top other side effects for these people *:

  • Joint Pain (166 people, 27.21%)
  • Pain In Extremity (128 people, 20.98%)
  • Pain (124 people, 20.33%)
  • Rashes (98 people, 16.07%)
  • Rheumatoid Arthritis (83 people, 13.61%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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