Review: could Methotrexate cause Photosensitivity Reaction?


Photosensitivity reaction is found among people who take Methotrexate, especially for people who are female, 50-59 old , have been taking the drug for 1 - 2 years, also take medication Folic Acid, and have Rheumatoid arthritis . We study 150,778 people who have side effects while taking Methotrexate from FDA and social media. Among them, 178 have Photosensitivity reaction. Find out below who they are, when they have Photosensitivity reaction and more.

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Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 160,929 users)

Photosensitivity Reaction

Photosensitivity reaction has been reported by people with toothaches, hypotension, rashes, diarrhea, heart palpitations (latest reports from 5,432 Photosensitivity reaction patients).

On Aug, 25, 2016

150,778 people reported to have side effects when taking Methotrexate.
Among them, 178 people (0.12%) have Photosensitivity Reaction

Number of reports submitted per year:

Could Methotrexate cause Photosensitivity reaction?

Time on Methotrexate when people have Photosensitivity Reaction *:

  • < 1 month: 7.14 %
  • 1 - 6 months: 21.43 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 35.71 %
  • 2 - 5 years: 28.57 %
  • 5 - 10 years: 7.14 %
  • 10+ years: 0.0 %

Gender of people who have Photosensitivity Reaction when taking Methotrexate *:

  • female: 55.69 %
  • male: 44.31 %

Age of people who have Photosensitivity Reaction when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 10.64 %
  • 10-19: 12.77 %
  • 20-29: 1.42 %
  • 30-39: 8.51 %
  • 40-49: 17.73 %
  • 50-59: 26.95 %
  • 60+: 21.99 %

Severity if Photosensitivity Reaction when taking Methotrexate **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

How people recovered from Photosensitivity Reaction **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (75 people)
  • Acute Lymphocytic Leukaemia (17 people)
  • Psoriatic Arthropathy (12 people)
  • Psoriasis (9 people)
  • Drug Dependence (6 people)

Top co-used drugs for these people *:

  • Folic Acid (44 people)
  • Enbrel (36 people)
  • Prednisone (32 people)
  • Humira (30 people)
  • Voriconazole (29 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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