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Review: could Methotrexate cause Photosensitivity reaction?

Summary: Photosensitivity reaction is found among people who take Methotrexate, especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years, also take medication Folic acid, and have Rheumatoid arthritis.

We study 129,882 people who have side effects while taking Methotrexate from FDA and social media. Among them, 198 have Photosensitivity reaction. Find out below who they are, when they have Photosensitivity reaction and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Photosensitivity reaction >>>

 

 

 

 

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,224 Methotrexate users)

Photosensitivity reaction

Photosensitivity reaction has been reported by people with high blood pressure, depression, rheumatoid arthritis, high blood cholesterol, multiple sclerosis. (latest reports from 6,475 Photosensitivity reaction patients)

On Jan, 26, 2015: 129,882 people reported to have side effects when taking Methotrexate. Among them, 198 people (0.15%) have Photosensitivity Reaction.

Trend of Photosensitivity reaction in Methotrexate reports

Time on Methotrexate when people have Photosensitivity reaction * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Photosensitivity reaction5.26%26.32%10.53%26.32%26.32%5.26%0.00%

Gender of people who have Photosensitivity reaction when taking Methotrexate * :

FemaleMale
Photosensitivity reaction63.86%36.14%

Age of people who have Photosensitivity reaction when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Photosensitivity reaction0.00%3.30%12.64%3.30%8.24%21.98%28.02%22.53%

Severity of Photosensitivity reaction when taking Methotrexate ** :

leastmoderateseveremost severe
Photosensitivity reaction0.00%100.00%0.00%0.00%

How people recovered from Photosensitivity reaction ** :

while on the drugafter off the drugnot yet
Photosensitivity reaction0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (79 people, 39.90%)
  2. Psoriatic arthropathy (10 people, 5.05%)
  3. Acute lymphocytic leukaemia (10 people, 5.05%)
  4. Psoriasis (8 people, 4.04%)
  5. Drug dependence (6 people, 3.03%)

Top co-used drugs for these people * :

  1. Folic acid (60 people, 30.30%)
  2. Enbrel (54 people, 27.27%)
  3. Prednisone (53 people, 26.77%)
  4. Humira (30 people, 15.15%)
  5. Methotrexate sodium (21 people, 10.61%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Photosensitivity Reaction while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Photosensitivity Reaction
- support group for people who take Methotrexate
- support group for people who have Photosensitivity Reaction

Recent conversations of related support groups:

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Is it safe to take zocalo if you are taking humora and methotrexate
    Is it safe to take all three of these together? I need to know if there is any adverse side effects of taking these drugs at the same time?
  • Does anyone take oral methotrexate and use topical magnesium chloride oil. if you do, do you have any side effects?
    I would like to try the Magnesium Chloride topical oil, but because of the oral MTX, I was wondering if anyone was taking/using this combination and if there were any side effects to watch for.....
  • Can viral myositis make my mysathenai gravis flare up? (1 answer)
    I am feeling weak, out of breath, and have difficulty walking due to my swelling, achiness, and slight pain! I was feeling fine just a few weeks ago......... had traveled and had no complaints........
  • Hlab27 antigen and unexplained scratches caused by accutane
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) unexplained scratches in same location, forearms, lower thigh (by knee) fingers. Scratches always are in a line with a break in the line. When a woman hits menopause hormones cease and when this happens the path that Accutane takes to cease sebaceous gland function, skin proliferation ceases. Therefore, my friends the HLA B27 (abnormal antigen targeted for skin proliferation does not know where to go so it randomly attacks whatever organ it chooses. Accutane if I remember correctly and I do have proof, permanently alters DNA. There is no other way orally ingesting a retinolic acid it could control skin, hormonal cesessation. I have only been diagnosed thus far with psoriatic arthritis with no other explanations for these other symptoms. I wonder why this is and I also wonder why dermatologists refuse to take a biopsy of my skin to rule out cell skin proliferation dysfunction. What will this damaging drug attack next. Do no be fooled by Dr.s who tell you that you took this drug so long ago how could this be. Well folks, it is because it has already changed your DNA to the HLAB27 antigen. My question also is, what was supposed to be where this abnormal DNA antigen is and how come this antigen only shows up at menopause. My disease (autoimmune) is progressive) and has already attacked nervous, muscle, skin, joints etc. Interesting
  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?

More questions for: Methotrexate, Photosensitivity reaction

You may be interested at these reviews (Write a review):

  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen I gained 29 pounds in two days. My doctor put me on lasix and potassium for several weeks. I quit using the spiriva when my other doctor asked if I was on any new meds. Spiriva was the only new medicine. When I stopped using it the swelling went away.
  • Personalized review of arava (1 response)
    Have had RA for 10 years and was on Methotrexate those 10 years. Had nose bleeds which got progressively worse over the years and began to effect my quality of living. Doctor said it could NOT be the drug, but according to eHealth Me, it could. At urging of an ENT, I stopped taking Methotrexate and the nose bleeds have now almost completely stopped. My doctor put me on Arava 3 days ago and I am on eHealth to study the effects of it.

More reviews for: Methotrexate, Photosensitivity reaction

Comments from related studies:

  • From this study (2 years ago):

  • violet brown on Dec, 3, 2012:

    I'm a 52 y/o female with RA, Sjogrens and fibromyalgia. I've been on Humira & methotrexate for about 7 years. Sinusitis symptoms off and on, usually after Humira injection or day after taking mtx. Infection needing antibiotic only a few times. Frustrating, but better than hurting, fatigue and joint degeneration.

    Reply

    vijay singh on Jul, 3, 2012:

    I am taking vitamin-E and vitamin-B complex regularly daily and Vitamin-A seldom from last two months. Now I saw that there is swelling on my finge's tip. Please suggest me some rimedy.

    Reply

    Debby on Jun, 29, 2011:

    I have been taking Gabapentin, 600 mg at night, for over two years due to lumbar decompression and fusion of L4-L5. During the same year I had C4-C7 fused as well. I take a 10 milligram Valium every night. Due to these surgeries I have been totally incapacitated for over a year. I am also a 62 year old female. Recently I gradually started getting back into playing golf, as well as other more physical activities. While playing golf I started noticing that I was getting a terrine rash. It started at my ankles and have now worked its way up to my knees, right where the sun hits. It looks terrible and my dermatologist took a biopsy today. Could it be due to photosensity caused by Valium and Gabapentin? The doctor says that it's actually blood vessels breaking or leaking under the skin. It looks terrible, and when I stand I feel a sensation of pins and needles in my lower legs. I don't know what to think or do. I do not want to be housebound any longer.

    Reply

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