Methotrexate and Premature menopause - from FDA reports


Summary

Premature menopause is found among people who take Methotrexate, especially for people who are 40-49 old , have been taking the drug for 6 - 12 months, also take medication Pyridoxine Hcl, and have Rheumatoid arthritis. This review analyzes which people have Premature menopause with Methotrexate. It is created by eHealthMe based on reports of 223,372 people who have side effects when taking Methotrexate from FDA, and is updated regularly.

What to expect?

If you take Methotrexate and have Premature menopause, find out what symptoms you could have in 1 year or longer.

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On Apr, 28, 2017

223,372 people reported to have side effects when taking Methotrexate.
Among them, 24 people (0.01%) have Premature Menopause


Number of reports submitted per year:

Could Methotrexate cause Premature menopause?

Time on Methotrexate when people have Premature Menopause *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Age of people who have Premature Menopause when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 16.67 %
  • 20-29: 5.56 %
  • 30-39: 27.78 %
  • 40-49: 50.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (13 people, 54.17%)
  • Nausea (5 people, 20.83%)
  • Bone Sarcoma (4 people, 16.67%)
  • Preventive Health Care (3 people, 12.50%)
  • Gestational Trophoblastic Tumor (2 people, 8.33%)

Top co-used drugs for these people *:

  • Pyridoxine Hcl (5 people, 20.83%)
  • Ifosfamide (4 people, 16.67%)
  • Cisplatin (4 people, 16.67%)
  • Rabeprazole Sodium (3 people, 12.50%)
  • Prednisolone (3 people, 12.50%)

Top other side effects for these people *:

  • Weight Increased (6 people, 25.00%)
  • Rashes (6 people, 25.00%)
  • Itching (5 people, 20.83%)
  • Hypothyroidism (5 people, 20.83%)
  • Amenorrhea (4 people, 16.67%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Premature menopause when taking Methotrexate?

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 226,881 users)

Premature Menopause

Premature menopause has been reported by people with birth control, depression, multiple sclerosis, metastatic malignant melanoma, malignant melanoma (latest reports from 818 Premature menopause patients).

Browse all side effects of Methotrexate

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Drugs that are associated with Premature menopause

Premature menopause

Could your condition cause Premature menopause

Premature menopause

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What would happen?

Forecast new side effects and undetected conditions when you take Methotrexate and have Premature menopause.

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