Methotrexate and Progressive multifocal leukoencephalopathy - from FDA reports


Summary

Progressive multifocal leukoencephalopathy is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 5 - 10 years, also take medication Prednisone, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 323 have Progressive multifocal leukoencephalopathy. Find out below who they are, when they have Progressive multifocal leukoencephalopathy and more.

What to expect?

If you take Methotrexate and have Progressive multifocal leukoencephalopathy, find out what symptoms you could have in 1 year or longer.

You are not alone!

Join a support group for people who take Methotrexate and have Progressive multifocal leukoencephalopathy

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA since 1977. Our tools are simple to use, anonymous and free. Start now >>>

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,557 users)

Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells) has been reported by people with multiple sclerosis, relapsing-remitting multiple sclerosis, chronic lymphocytic leukaemia, non-hodgkin's lymphoma, rheumatoid arthritis (latest reports from 7,273 Progressive multifocal leukoencephalopathy patients).

On Jan, 21, 2017

209,150 people reported to have side effects when taking Methotrexate.
Among them, 323 people (0.15%) have Progressive Multifocal Leukoencephalopathy


Number of reports submitted per year:

Could Methotrexate cause Progressive multifocal leukoencephalopathy?

Time on Methotrexate when people have Progressive Multifocal Leukoencephalopathy *:

  • < 1 month: 10 %
  • 1 - 6 months: 24 %
  • 6 - 12 months: 18 %
  • 1 - 2 years: 2 %
  • 2 - 5 years: 10 %
  • 5 - 10 years: 32 %
  • 10+ years: 4 %

Gender of people who have Progressive Multifocal Leukoencephalopathy when taking Methotrexate *:

  • female: 64.67 %
  • male: 35.33 %

Age of people who have Progressive Multifocal Leukoencephalopathy when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.71 %
  • 10-19: 7.12 %
  • 20-29: 2.49 %
  • 30-39: 6.05 %
  • 40-49: 17.79 %
  • 50-59: 22.78 %
  • 60+: 43.06 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (137 people, 42.41%)
  • Tonsil Cancer (21 people, 6.50%)
  • Systemic Lupus Erythematosus (20 people, 6.19%)
  • Polymyositis (15 people, 4.64%)
  • Acute Lymphocytic Leukemia (all) (14 people, 4.33%)

Top co-used drugs for these people *:

  • Prednisone (62 people, 19.20%)
  • Folic Acid (53 people, 16.41%)
  • Cyclophosphamide (50 people, 15.48%)
  • Prednisolone (42 people, 13.00%)
  • Rituxan (41 people, 12.69%)

Top other side effects for these people *:

  • Speech Impairment (adult) (31 people, 9.60%)
  • Jc Virus Infection (31 people, 9.60%)
  • Pneumonia (23 people, 7.12%)
  • Drug Ineffective (18 people, 5.57%)
  • Confusion (18 people, 5.57%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Progressive multifocal leukoencephalopathy when taking Methotrexate?

Browse all side effects of Methotrexate

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy

Could your condition cause Progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy

Related studies

Can you answer these questions?

More questions for: Methotrexate, Progressive multifocal leukoencephalopathy

You may be interested in these reviews

More reviews for: Methotrexate, Progressive multifocal leukoencephalopathy