Methotrexate and Pulmonary fibrosis - from FDA reports


Summary

Pulmonary fibrosis is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 2 - 5 years, also take medication Folic Acid, and have Rheumatoid arthritis. This review analyzes which people have Pulmonary fibrosis with Methotrexate. It is created by eHealthMe based on reports of 223,372 people who have side effects when taking Methotrexate from FDA, and is updated regularly.

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On Apr, 28, 2017

223,372 people reported to have side effects when taking Methotrexate.
Among them, 1,278 people (0.57%) have Pulmonary Fibrosis


Number of reports submitted per year:

Could Methotrexate cause Pulmonary fibrosis?

Time on Methotrexate when people have Pulmonary Fibrosis *:

  • < 1 month: 6.87 %
  • 1 - 6 months: 13.74 %
  • 6 - 12 months: 10.31 %
  • 1 - 2 years: 15.27 %
  • 2 - 5 years: 25.95 %
  • 5 - 10 years: 18.7 %
  • 10+ years: 9.16 %

Gender of people who have Pulmonary Fibrosis when taking Methotrexate *:

  • female: 58.76 %
  • male: 41.24 %

Age of people who have Pulmonary Fibrosis when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 1.11 %
  • 10-19: 2.11 %
  • 20-29: 0.81 %
  • 30-39: 4.03 %
  • 40-49: 4.73 %
  • 50-59: 17.12 %
  • 60+: 70.09 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (710 people, 55.56%)
  • High Blood Pressure (43 people, 3.36%)
  • Psoriatic Arthropathy (39 people, 3.05%)
  • Osteoporosis (31 people, 2.43%)
  • Psoriasis (26 people, 2.03%)

Top co-used drugs for these people *:

  • Folic Acid (266 people, 20.81%)
  • Enbrel (239 people, 18.70%)
  • Humira (205 people, 16.04%)
  • Remicade (192 people, 15.02%)
  • Prednisone (174 people, 13.62%)

Top other side effects for these people *:

  • Pneumonia (265 people, 20.74%)
  • Breathing Difficulty (171 people, 13.38%)
  • Interstitial Lung Disease (136 people, 10.64%)
  • Cough (114 people, 8.92%)
  • Fever (110 people, 8.61%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Pulmonary fibrosis when taking Methotrexate?

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 226,881 users)

Pulmonary Fibrosis

Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs) has been reported by people with rheumatoid arthritis, idiopathic pulmonary fibrosis, osteoporosis, high blood pressure, atrial fibrillation/flutter (latest reports from 23,713 Pulmonary fibrosis patients).

Browse all side effects of Methotrexate

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Drugs that are associated with Pulmonary fibrosis

Pulmonary fibrosis

Could your condition cause Pulmonary fibrosis

Pulmonary fibrosis

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What would happen?

Forecast new side effects and undetected conditions when you take Methotrexate and have Pulmonary fibrosis.

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