eHealthMe - Personalized health information & community eHealthMe - Personalized health information & community

Personalized health information & community

All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Check symptoms   -   Check drugs   -   Compare drugs   -   Join a support group   -   More tools

Review: could Methotrexate cause Pulmonary fibrosis (Idiopathic pulmonary fibrosis)?

Summary: Pulmonary fibrosis is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Folic acid, and have Rheumatoid arthritis.

We study 129,925 people who have side effects while taking Methotrexate from FDA and social media. Among them, 894 have Pulmonary fibrosis. Find out below who they are, when they have Pulmonary fibrosis and more.

You are not alone: join a support group for people who take Methotrexate and have Pulmonary fibrosis >>>



Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,267 Methotrexate users)

Pulmonary fibrosis

Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs) has been reported by people with rheumatoid arthritis, osteoporosis, high blood pressure, high blood cholesterol, primary pulmonary hypertension. (latest reports from 10,006 Pulmonary fibrosis patients)

On Apr, 16, 2015: 129,908 people reported to have side effects when taking Methotrexate. Among them, 894 people (0.69%) have Pulmonary Fibrosis.

Trend of Pulmonary fibrosis in Methotrexate reports

Time on Methotrexate when people have Pulmonary fibrosis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Pulmonary fibrosis7.11%16.89%11.56%15.56%24.89%15.56%8.44%

Gender of people who have Pulmonary fibrosis when taking Methotrexate * :

Pulmonary fibrosis61.91%38.09%

Age of people who have Pulmonary fibrosis when taking Methotrexate * :

Pulmonary fibrosis0.00%0.99%1.98%0.99%3.58%4.69%16.17%71.60%

Severity of Pulmonary fibrosis when taking Methotrexate ** :

leastmoderateseveremost severe
Pulmonary fibrosis0.00%0.00%100.00%0.00%

How people recovered from Pulmonary fibrosis ** :


Top conditions involved for these people * :

  1. Rheumatoid arthritis (498 people, 55.70%)
  2. Osteoporosis (23 people, 2.57%)
  3. Psoriatic arthropathy (22 people, 2.46%)
  4. Depression (21 people, 2.35%)
  5. Hypertension (19 people, 2.13%)

Top co-used drugs for these people * :

  1. Folic acid (321 people, 35.91%)
  2. Humira (193 people, 21.59%)
  3. Remicade (181 people, 20.25%)
  4. Prednisone (161 people, 18.01%)
  5. Enbrel (137 people, 15.32%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of methotrexate and pulmonary fibrosis on

Do you have Pulmonary Fibrosis while taking Methotrexate?




You are not alone! Join a support group on :
- support group for people who take Methotrexate and have Pulmonary Fibrosis
- support group for people who take Methotrexate
- support group for people who have Pulmonary Fibrosis

Drugs in real world that are associated with:

Could your condition cause:

Recent related drug studies (Check your drugs):

Recent Methotrexate related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


About - Terms of service - Privacy policy - Press - Testimonials - Contact us -

© 2015 All rights reserved. Use of this site constitutes acceptance of's terms of service and privacy policy.