Review: could Methotrexate cause Pulmonary fibrosis (Idiopathic pulmonary fibrosis)?
Summary: Pulmonary fibrosis is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Folic acid, and have Rheumatoid arthritis.
We study 129,925 people who have side effects while taking Methotrexate from FDA and social media. Among them, 894 have Pulmonary fibrosis. Find out below who they are, when they have Pulmonary fibrosis and more.
You are not alone: join a support group for people who take Methotrexate and have Pulmonary fibrosis >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,267 Methotrexate users)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs) has been reported by people with rheumatoid arthritis, osteoporosis, high blood pressure, high blood cholesterol, primary pulmonary hypertension. (latest reports from 10,006 Pulmonary fibrosis patients)
On Apr, 16, 2015: 129,908 people reported to have side effects when taking Methotrexate. Among them, 894 people (0.69%) have Pulmonary Fibrosis.
Time on Methotrexate when people have Pulmonary fibrosis * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Pulmonary fibrosis||7.11%||16.89%||11.56%||15.56%||24.89%||15.56%||8.44% |
Gender of people who have Pulmonary fibrosis when taking Methotrexate * :
|Pulmonary fibrosis||61.91%||38.09% |
Age of people who have Pulmonary fibrosis when taking Methotrexate * :
|Pulmonary fibrosis||0.00%||0.99%||1.98%||0.99%||3.58%||4.69%||16.17%||71.60% |
Severity of Pulmonary fibrosis when taking Methotrexate ** :
|least||moderate||severe||most severe |
|Pulmonary fibrosis||0.00%||0.00%||100.00%||0.00% |
How people recovered from Pulmonary fibrosis ** :
Top conditions involved for these people * :
- Rheumatoid arthritis (498 people, 55.70%)
- Osteoporosis (23 people, 2.57%)
- Psoriatic arthropathy (22 people, 2.46%)
- Depression (21 people, 2.35%)
- Hypertension (19 people, 2.13%)
Top co-used drugs for these people * :
- Folic acid (321 people, 35.91%)
- Humira (193 people, 21.59%)
- Remicade (181 people, 20.25%)
- Prednisone (161 people, 18.01%)
- Enbrel (137 people, 15.32%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Get connected: join our support group of methotrexate and pulmonary fibrosis on
Do you have Pulmonary Fibrosis while taking Methotrexate?
You are not alone! Join a support group on :
- support group for people who take Methotrexate and have Pulmonary Fibrosis
- support group for people who take Methotrexate
- support group for people who have Pulmonary Fibrosis
Drugs in real world that are associated with:
Could your condition cause:
- A study of drug interactions between Folic Acid, Orencia, Methotrexate for a 45-year old woman with Arthritis - Rheumatoid. The patient has Joint Stiffness
- A study of drug interactions between Remicade, Methotrexate for a 47-year old woman with Sarcoidosis. The patient has Burning Eyes, Burning Eyes, Shortness Of Breath, Painful Respiration
- A study of drug interactions between Humira, Folic Acid, Methotrexate for a 71-year old woman with Rheumatoid Arthritis. The patient has Depression, Skin Graft, Eyes - Yellow, Fatigue, Nausea And Vomiting, Confusional State, Tremor
- A study of side effects of Methotrexate for a 55-year old woman with Rheumatoid Arthritis. The patient has Diarrhoea
- A study of drug interactions between Plaquenil, Folic Acid, Vitamin D, Methotrexate, Lamictal for a 47-year old woman with Rheumatoid Arthritis, Seizures. The patient has Broken Jaw
Recent Methotrexate related drug comparison:
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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