Review: could Methotrexate cause Rash?


Summary

Rash is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Humira, and have Rheumatoid arthritis . We study 191,458 people who have side effects while taking Methotrexate from FDA and social media. Among them, 6,420 have Rash. Find out below who they are, when they have Rash and more.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 205,731 users)

Rash

Rash has been reported by people with breathing difficulty, fever, rashes, drug ineffective, itching (latest reports from 254,289 Rash patients).

On Sep, 16, 2016

191,458 people reported to have side effects when taking Methotrexate.
Among them, 6,420 people (3.35%) have Rash


Number of reports submitted per year:

Could Methotrexate cause Rash?

Time on Methotrexate when people have Rash *:

  • < 1 month: 33.92 %
  • 1 - 6 months: 19.6 %
  • 6 - 12 months: 11.23 %
  • 1 - 2 years: 9.91 %
  • 2 - 5 years: 11.67 %
  • 5 - 10 years: 9.47 %
  • 10+ years: 3.96 %

Gender of people who have Rash when taking Methotrexate *:

  • female: 75.66 %
  • male: 24.34 %

Age of people who have Rash when taking Methotrexate *:

  • 0-1: 0.37 %
  • 2-9: 2.73 %
  • 10-19: 5.74 %
  • 20-29: 3.72 %
  • 30-39: 7.77 %
  • 40-49: 16.82 %
  • 50-59: 26.08 %
  • 60+: 36.76 %

Severity if Rash when taking Methotrexate **:

  • least: 0.0 %
  • moderate: 73.33 %
  • severe: 13.33 %
  • most severe: 13.33 %

How people recovered from Rash **:

  • while on drug: 7.69 %
  • after off the drug: 0.0 %
  • not yet: 92.31 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (3,630 people, 56.54%)
  • Psoriatic Arthropathy (488 people, 7.60%)
  • Pain (381 people, 5.93%)
  • Hypertension (380 people, 5.92%)
  • Psoriasis (350 people, 5.45%)

Top co-used drugs for these people *:

  • Humira (1,934 people, 30.12%)
  • Folic Acid (1,638 people, 25.51%)
  • Enbrel (1,529 people, 23.82%)
  • Prednisone (794 people, 12.37%)
  • Remicade (658 people, 10.25%)

Top other side effects for these people *:

  • Pruritus (906 people, 14.11%)
  • Arthralgia (795 people, 12.38%)
  • Pain (748 people, 11.65%)
  • Pyrexia (723 people, 11.26%)
  • Nausea (586 people, 9.13%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Rash when taking Methotrexate?

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