Review: could Methotrexate cause Rash?


Summary

Rash is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Folic Acid, and have Rheumatoid arthritis . We study 128,586 people who have side effects while taking Methotrexate from FDA and social media. Among them, 4,367 have Rash. Find out below who they are, when they have Rash and more.

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Methotrexate

It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 129,243 users)

Rash

Rash has been reported by people with breathing difficulty, erythema multiforme, fever, pain, drug ineffective (latest reports from 142,134 Rash patients).

On Jul, 23, 2016

128,586 people reported to have side effects when taking Methotrexate.
Among them, 4,367 people (3.4%) have Rash


Number of reports submitted per year:

Could Methotrexate cause Rash?

Time on Methotrexate when people have Rash *:

  • < 1 month: 36.49 %
  • 1 - 6 months: 20.09 %
  • 6 - 12 months: 12.24 %
  • 1 - 2 years: 8.08 %
  • 2 - 5 years: 11.32 %
  • 5 - 10 years: 8.08 %
  • 10+ years: 3.7 %

Gender of people who have Rash when taking Methotrexate *:

  • female: 74.29 %
  • male: 25.71 %

Age of people who have Rash when taking Methotrexate *:

  • 0-1: 0.36 %
  • 2-9: 3.13 %
  • 10-19: 6.86 %
  • 20-29: 3.9 %
  • 30-39: 8.14 %
  • 40-49: 17.05 %
  • 50-59: 23.73 %
  • 60+: 36.81 %

Severity if Rash when taking Methotrexate **:

  • least: 5 %
  • moderate: 65 %
  • severe: 15 %
  • most severe: 15 %

How people recovered from Rash **:

  • while on drug: 7.14 %
  • after off the drug: 7.14 %
  • not yet: 85.71 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (2,116 people)
  • Psoriatic Arthropathy (224 people)
  • Hypertension (186 people)
  • Pain (183 people)
  • Psoriasis (168 people)

Top co-used drugs for these people *:

  • Folic Acid (1,200 people)
  • Humira (1,194 people)
  • Enbrel (808 people)
  • Prednisone (574 people)
  • Remicade (511 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Rash when taking Methotrexate?


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Drugs that are associated with Rash

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Could your condition cause Rash

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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