Methotrexate and Renal failure - from FDA reports


Summary

Renal failure is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Humira, and have Rheumatoid arthritis. This review analyzes which people have Renal failure with Methotrexate. It is created by eHealthMe based on reports of 223,372 people who have side effects when taking Methotrexate from FDA, and is updated regularly.

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On May, 16, 2017

223,372 people reported to have side effects when taking Methotrexate.
Among them, 1,796 people (0.8%) have Renal Failure


Number of reports submitted per year:

Could Methotrexate cause Renal failure?

Time on Methotrexate when people have Renal Failure *:

  • < 1 month: 49.26 %
  • 1 - 6 months: 9.14 %
  • 6 - 12 months: 6.19 %
  • 1 - 2 years: 9.44 %
  • 2 - 5 years: 11.21 %
  • 5 - 10 years: 7.96 %
  • 10+ years: 6.78 %

Gender of people who have Renal Failure when taking Methotrexate *:

  • female: 55.61 %
  • male: 44.39 %

Age of people who have Renal Failure when taking Methotrexate *:

  • 0-1: 0.65 %
  • 2-9: 2.59 %
  • 10-19: 12.95 %
  • 20-29: 3.24 %
  • 30-39: 4.89 %
  • 40-49: 12.73 %
  • 50-59: 20.22 %
  • 60+: 42.73 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (655 people, 36.47%)
  • High Blood Pressure (111 people, 6.18%)
  • Acute Lymphocytic Leukemia (all) (94 people, 5.23%)
  • Osteoporosis (81 people, 4.51%)
  • Pain (67 people, 3.73%)

Top co-used drugs for these people *:

  • Humira (291 people, 16.20%)
  • Prednisone (273 people, 15.20%)
  • Folic Acid (259 people, 14.42%)
  • Enbrel (215 people, 11.97%)
  • Remicade (204 people, 11.36%)

Top other side effects for these people *:

  • Sepsis (262 people, 14.59%)
  • Pneumonia (222 people, 12.36%)
  • Fever (209 people, 11.64%)
  • Diarrhea (209 people, 11.64%)
  • Anaemia (201 people, 11.19%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Renal failure when taking Methotrexate?

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 226,881 users)

Renal Failure

Renal failure (kidney dysfunction) has been reported by people with high blood pressure, multiple myeloma, coronary artery bypass, diabetes, rheumatoid arthritis (latest reports from 85,558 Renal failure patients).

Browse all side effects of Methotrexate

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Drugs that are associated with Renal failure

Renal failure

Could your condition cause Renal failure

Renal failure

Related studies

What would happen?

Forecast new side effects and undetected conditions when you take Methotrexate and have Renal failure.

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