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Review: could Methotrexate cause Renal failure (Acute kidney failure)?





Summary: Renal failure is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Prednisone, and have Rheumatoid arthritis.

We study 129,858 people who have side effects while taking Methotrexate from FDA and social media. Among them, 1,150 have Renal failure. Find out below who they are, when they have Renal failure and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Renal failure >>>

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)

Renal failure

Renal failure (kidney dysfunction) has been reported by people with high blood pressure, coronary artery bypass, diabetes, multiple myeloma, pain.(latest reports from Renal failure 72,089 patients)

On Dec, 2, 2014: 129,841 people reported to have side effects when taking Methotrexate. Among them, 1,417 people (1.09%) have Renal Failure.

Trend of Renal failure in Methotrexate reports

Time on Methotrexate when people have Renal failure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Renal failure48.57%8.57%6.79%8.57%15.71%7.14%4.64%

Gender of people who have Renal failure when taking Methotrexate * :

FemaleMale
Renal failure58.46%41.54%

Age of people who have Renal failure when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Renal failure0.72%3.06%15.38%3.70%4.91%13.12%19.81%39.29%

Severity of Renal failure when taking Methotrexate ** :

leastmoderateseveremost severe
Renal failure0.00%50.00%50.00%0.00%

How people recovered from Renal failure ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (461 people, 32.53%)
  2. Hypertension (77 people, 5.43%)
  3. Osteoporosis (72 people, 5.08%)
  4. Acute lymphocytic leukaemia (67 people, 4.73%)
  5. Prophylaxis (46 people, 3.25%)

Top co-used drugs for these people * :

  1. Prednisone (312 people, 22.02%)
  2. Folic acid (287 people, 20.25%)
  3. Humira (219 people, 15.46%)
  4. Cyclophosphamide (218 people, 15.38%)
  5. Remicade (197 people, 13.90%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Renal Failure while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Renal Failure
- support group for people who take Methotrexate
- support group for people who have Renal Failure

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    (Asked by a 49 year old woman who has Scratches, Swelling, Burning, Nerve, Muscle Pain, Conjunctivitis, and takes Methotrexate)
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) une ...
  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    (Asked by a 57 year old woman who has Migraine Without Aura, Anxiety And Stress, Major Depression With Psychotic Features, Bilateral Multilobar Pneumonia, Ankylosing Spondylitis, and takes Zyprexa, Methotrexate)
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?
  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area... (2 answers)
    (Asked by a 56 year old woman who has Hign Blood Pressure, Osteoporosis Postmenopausal, Rheumatoid Arthritis, and takes Methotrexate)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms s ...
  • Can i take marijuana while taking gilenya
    (Asked by a 36 year old woman who has MS, and takes Gilenya)
    Hello i would like to know if is safe to have marijuane with gilenya and methotraxate
  • Creatinine rising on crestor & causing kidney failure (1 answer)
    (Asked by a 64 year old man who has Kidney Failure, and takes Crestor)
    Husband been on Crestor for 3 years...Creatinine been increasing and he already is a diabetic and been watching his kidney function. Everything I read online points to the Crestor causing Kidney Failure but the doctors REFUSE to listen too us and now he is heading toward dialysis or a Kidney Transpl ...

More questions for: Methotrexate, Renal failure

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    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
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