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Review: could Methotrexate cause Renal failure (Acute kidney failure)?

Summary: Renal failure is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Prednisone, and have Rheumatoid arthritis.

We study 129,897 people who have side effects while taking Methotrexate from FDA and social media. Among them, 1,417 have Renal failure. Find out below who they are, when they have Renal failure and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Renal failure >>>

 

 

 

 

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,236 Methotrexate users)

Renal failure

Renal failure (kidney dysfunction) has been reported by people with high blood pressure, coronary artery bypass, multiple myeloma, diabetes, pain. (latest reports from 72,154 Renal failure patients)

On Feb, 9, 2015: 129,882 people reported to have side effects when taking Methotrexate. Among them, 1,417 people (1.09%) have Renal Failure.

Trend of Renal failure in Methotrexate reports

Time on Methotrexate when people have Renal failure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Renal failure48.57%8.57%6.79%8.57%15.71%7.14%4.64%

Gender of people who have Renal failure when taking Methotrexate * :

FemaleMale
Renal failure58.46%41.54%

Age of people who have Renal failure when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Renal failure0.72%3.06%15.38%3.70%4.91%13.12%19.81%39.29%

Severity of Renal failure when taking Methotrexate ** :

leastmoderateseveremost severe
Renal failure0.00%50.00%50.00%0.00%

How people recovered from Renal failure ** :

n/a

Top conditions involved for these people * :

  1. Rheumatoid arthritis (461 people, 32.53%)
  2. Hypertension (77 people, 5.43%)
  3. Osteoporosis (72 people, 5.08%)
  4. Acute lymphocytic leukaemia (67 people, 4.73%)
  5. Prophylaxis (46 people, 3.25%)

Top co-used drugs for these people * :

  1. Prednisone (312 people, 22.02%)
  2. Folic acid (287 people, 20.25%)
  3. Humira (219 people, 15.46%)
  4. Cyclophosphamide (218 people, 15.38%)
  5. Remicade (197 people, 13.90%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of methotrexate and renal failure on

Do you have Renal Failure while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Renal Failure
- support group for people who take Methotrexate
- support group for people who have Renal Failure

Drugs in real world that are associated with:

Could your condition cause:

Recent related drug studies (Check your drugs):

Recent Methotrexate related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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