Methotrexate and Renal failure - from FDA reports


Summary

Renal failure is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Prednisone, and have High blood pressure. This review analyzes which people have Renal failure with Methotrexate. It is created by eHealthMe based on reports of 231,270 people who have side effects when taking Methotrexate from FDA , and is updated regularly.

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On Sep, 26, 2017

231,270 people reported to have side effects when taking Methotrexate.
Among them, 2,121 people (0.92%) have Renal failure


Number of reports submitted per year:

Could Methotrexate cause Renal failure?

Time on Methotrexate when people have Renal failure *:

  • < 1 month: 48.46 %
  • 1 - 6 months: 9.52 %
  • 6 - 12 months: 6.44 %
  • 1 - 2 years: 9.24 %
  • 2 - 5 years: 11.76 %
  • 5 - 10 years: 7.56 %
  • 10+ years: 7.0 %

Gender of people who have Renal failure when taking Methotrexate *:

  • female: 55.67 %
  • male: 44.33 %

Age of people who have Renal failure when taking Methotrexate *:

  • 0-1: 0.54 %
  • 2-9: 2.76 %
  • 10-19: 12.19 %
  • 20-29: 3.12 %
  • 30-39: 4.86 %
  • 40-49: 12.97 %
  • 50-59: 19.58 %
  • 60+: 43.96 %

Top conditions involved for these people *:

  • High Blood Pressure (112 people, 5.28%)
  • Acute Lymphocytic Leukemia (all) (95 people, 4.48%)
  • Osteoporosis (81 people, 3.82%)
  • Preventive Health Care (68 people, 3.21%)
  • Pain (67 people, 3.16%)

Top co-used drugs for these people *:

  • Prednisone (336 people, 15.84%)
  • Humira (303 people, 14.29%)
  • Folic Acid (299 people, 14.10%)
  • Enbrel (280 people, 13.20%)
  • Remicade (257 people, 12.12%)

Top other side effects for these people *:

  • Sepsis (269 people, 12.68%)
  • Fever (248 people, 11.69%)
  • Pneumonia (226 people, 10.66%)
  • Diarrhea (212 people, 10.00%)
  • Anaemia (210 people, 9.90%)

* Approximation only. Some reports may have incomplete information.

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Do you have Renal failure when taking Methotrexate?

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Renal failure and drugs with ingredients of methotrexate sodium.

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Renal failure and Methotrexate from FDA and eHealthMe reports

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 234,878 users)

Renal failure

Renal failure (kidney dysfunction) has been reported by people with high blood pressure, multiple myeloma, diabetes, coronary artery bypass, pain (latest reports from 87,300 Renal failure patients).

Browse all side effects of Methotrexate

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