Review: could Methotrexate cause Shortness of breath (Breathing difficulty)?
Summary: Shortness of breath is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Folic acid, and have Rheumatoid arthritis.
We study 129,882 people who have side effects while taking Methotrexate from FDA and social media. Among them, 3,584 have Shortness of breath. Find out below who they are, when they have Shortness of breath and more.
You are not alone: join a mobile support group for people who take Methotrexate and have Shortness of breath >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,233 Methotrexate users)
Shortness of breath
Shortness of breath has been reported by people with high blood pressure, asthma, rheumatoid arthritis, pain, chronic obstructive pulmonary disease. (latest reports from 165,355 Shortness of breath patients)
On Jan, 29, 2015: 129,882 people reported to have side effects when taking Methotrexate. Among them, 3,585 people (2.76%) have Shortness Of Breath.
Time on Methotrexate when people have Shortness of breath * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Shortness of breath||18.95%||25.57%||8.90%||11.19%||18.26%||12.10%||5.02% |
Gender of people who have Shortness of breath when taking Methotrexate * :
|Shortness of breath||72.08%||27.92% |
Age of people who have Shortness of breath when taking Methotrexate * :
|Shortness of breath||0.51%||1.57%||3.43%||4.20%||7.78%||13.90%||22.17%||46.44% |
Severity of Shortness of breath when taking Methotrexate ** :
|least||moderate||severe||most severe |
|Shortness of breath||9.09%||54.55%||31.82%||4.55% |
How people recovered from Shortness of breath ** :
|while on the drug||after off the drug||not yet |
|Shortness of breath||5.00%||10.00%||85.00% |
Top conditions involved for these people * :
- Rheumatoid arthritis (2,219 people, 61.90%)
- Pain (273 people, 7.62%)
- Hypertension (244 people, 6.81%)
- Psoriatic arthropathy (213 people, 5.94%)
- Arthritis (139 people, 3.88%)
Top co-used drugs for these people * :
- Folic acid (1,334 people, 37.21%)
- Humira (1,111 people, 30.99%)
- Remicade (717 people, 20.00%)
- Prednisone (676 people, 18.86%)
- Enbrel (569 people, 15.87%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Shortness Of Breath while taking Methotrexate?
You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Shortness Of Breath
- support group for people who take Methotrexate
- support group for people who have Shortness Of Breath
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Drugs in real world that are associated with:
Could your condition cause:
Can you answer these questions (Ask a question):
- Does humira cause excessive sweating?
Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
- Can xeralto and an antihistimine cause dizziness, shortness of breath, tiredness, etc.
I also take a blood thinner, xeralto, for a-fib. I have been using a mouthwash of an antihistimine antacid mix for a day and a half.
- Would the tinnitus abate with if i discontinue methotrexate?
I've just begun my 4th year of Methotrexate for Rheumatoid issue, but it also alleviated my psoriasis. I am hesitant to discontinue because the benefits are great. However, the tinnitus is becoming unbearable and almost maddening. I will more likely consider talking to my doctor about changing medications if 1. The tinnitus subsides with the discontinuance of Methotrexate and if 2. Other rheumatoid medication would not have the same issues with tinnitus. Just discovered the possible connection minutes ago and am eager and hopeful. Please help. Thank you. -Celeste
- I suffer from hypotension after taking meal along with breathlessness and itching
after eating I fell as if I will faint n hav dyspnea n headache.. n if I try to walk then I hav severe itching all over the body ... if I don't take meal then I am fine
- Kindly tell me whether this treatment is accurate for spine tb?
have spinal tb and having treatment since 5 months..also a kidney dialysis patient..having two dialysis per week...i think this treatment is not effective because i am having severe back pain, severe pain in feet..nausea..and shortness of breath...
More questions for: Methotrexate, Shortness of breath
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I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.
I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(
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From this study (5 months ago):
Sarcoidosis caused complete heart block. Pacemaker implanted in December 2009 but for the past two years I have had palpitations caused by around 3.7 million ectopic heartbeats per year.
Sarcoidosis also in lungs and eyes. Extended use of Pred Forte caused development of cataracts, one of which has been removed and I am awaiting the second operation.
Breathlessness is caused by lack of oxygen entering the bloodstream and my ongoing heart problems
Rarely able to sleep properly due to pain, sleeping for about 20 minutes at a time when I become so exhausted that the pain can't keep me awake
Muscle and joint pain have made me weak and clumsy.Pain is felt all over, from head to toes along with muscle cramps and intense burning sensation to skin on lower legs.
ACE levels fluctuate but average 110 - 150.
Blood pressure on average is 150 / 78 - no treatment given
I also take Nefopam Hydrochloride (Acupan) for pain but this drug is not on the list.
Immobility, fatigue and constant pain have left me very depressed ad harbouring thoughts of suicide. My 15 year old granddaughter has lived with me since the death of my daughter 11 years ago and it is my hope that I will live long enough to see her settled in college and independent after which the only thing I have to look forward to is to end my own suffering.
IchikireiLV on Sep, 5, 2014:
I was so sorry to read your comment, but glad I encountered it. PLEASE PLEASE don't ever think of taking your own life! I know what it is like to suffer. I injured myself 7 yrs ago, got a spinal implant that failed, compressed my spine, corroded and left me with heavy metal toxicity which caused adrenal failure, hypothyroid and many other serious health conditions. I have lived a life of chronic pain, fatigue and difficulty, so I know exactly where you are coming from! Some days I am so weak and have so much pain that I cannot get out of bed or care for myself. At times I try to puch myself to do the simplest things and my body is so frail I can barely catch my breath and feel like I gave to crawl back to my bed, dripping in sweat, dehydrated and defeated... but I still go on in hopes that there will be a better day. I ENCOURAGE YOU TO SEE A PAIN MANAGEMENT DR. MONTHLY FOR MEDICATIONS TO CONTROL YOUR PAIN! This alone will improve your daily life immensely! Pain will make you depressed! I also use Savella. It helps with Neuropathy pain AND DEPRESSION. Dont give up because doctors arent helping you enough. MAKE THEM! Its unacceptable that they are not following thru but I myself have experienced this many times.. Find another better, more compassionate Dr. Read Dr. reviews online, start with a primary care family dr, a pain dr and a rhuematologist for Sarcoidosis... make sure the Dr. is experienced with Sarcoidosis.. if not, find another one. I hope this helps you and gives you a direction to follow. Once your pain is controlled, things will be a lot better. Good luck and wishes of health and most of all HOPE and HAPPINESS 😄😄
Kath Nugent on Aug, 26, 2014:
I was diagnosed with Lymphatic Sarcoidosis 15 years ago. After massive weight loss, a node in my neck the size of a small egg, and at the same time an
area of my gum opened up were i had a tooth removed 20 years earlier, Sarcoid grew out of this opening !!it was like a piece of green string. My GP & Consultant tried to pull it out but failed,it was about an inch long. i was sent away with no further appointment, So i went to see my Dentist who seemed to know what it was and sent me to the Hospital Dentist who did a jaw bone Scraping and arranged for the node in neck to be removed for biopsy, both biopsy came back as Sarcoidosis. i was then x rayed and was found to have it in on my lungs as well. at this point i had active Sarcoidosis in my Lymphatic system, bone, lungs. However it as never been active in my lungs !!! it did however eat away the inside of my nose, it attacked my eyes i almost went blind, i lost my balance,it was in my brain.
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