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Review: could Methotrexate cause Shortness of breath (Breathing difficulty)?

We study 129,821 people who have side effects while taking Methotrexate from FDA and social media. Among them, 3,582 have Shortness of breath. Find out below who they are, when they have Shortness of breath and more.

Get connected: join a mobile support group for people who take Methotrexate and have Shortness of breath >>>

Methotrexate

Methotrexate (latest outcomes from 131,137 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Shortness of breath

Shortness of breath (latest reports from 1,338,463 patients) has been reported by people with high blood pressure, asthma, rheumatoid arthritis, pain, chronic obstructive pulmonary disease.

On Sep, 16, 2014: 129,775 people reported to have side effects when taking Methotrexate. Among them, 3,582 people (2.76%) have Shortness Of Breath.

Trend of Shortness of breath in Methotrexate reports

Time on Methotrexate when people have Shortness of breath * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Shortness of breath19.04%25.69%8.94%11.24%18.35%12.16%4.59%

Gender of people who have Shortness of breath when taking Methotrexate * :

FemaleMale
Shortness of breath72.08%27.92%

Age of people who have Shortness of breath when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Shortness of breath0.51%1.57%3.43%4.20%7.79%13.85%22.19%46.46%

Severity of Shortness of breath when taking Methotrexate ** :

leastmoderateseveremost severe
Shortness of breath10.53%47.37%36.84%5.26%

How people recovered from Shortness of breath ** :

while on the drugafter off the drugnot yet
Shortness of breath5.56%11.11%83.33%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (2,218 people, 61.92%)
  2. Pain (273 people, 7.62%)
  3. Hypertension (244 people, 6.81%)
  4. Psoriatic arthropathy (213 people, 5.95%)
  5. Arthritis (139 people, 3.88%)

Top co-used drugs for these people * :

  1. Folic acid (1,334 people, 37.24%)
  2. Humira (1,111 people, 31.02%)
  3. Remicade (717 people, 20.02%)
  4. Prednisone (675 people, 18.84%)
  5. Enbrel (568 people, 15.86%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Shortness Of Breath while taking Methotrexate?

Get connected! Join a mobile support group:
- support group for people who take Methotrexate and have Shortness Of Breath
- support group for people who take Methotrexate
- support group for people who have Shortness Of Breath

Comments from related studies:

  • From this study (1 month ago):

  • Sarcoidosis caused complete heart block. Pacemaker implanted in December 2009 but for the past two years I have had palpitations caused by around 3.7 million ectopic heartbeats per year.

    Sarcoidosis also in lungs and eyes. Extended use of Pred Forte caused development of cataracts, one of which has been removed and I am awaiting the second operation.

    Breathlessness is caused by lack of oxygen entering the bloodstream and my ongoing heart problems

    Rarely able to sleep properly due to pain, sleeping for about 20 minutes at a time when I become so exhausted that the pain can't keep me awake

    Muscle and joint pain have made me weak and clumsy.Pain is felt all over, from head to toes along with muscle cramps and intense burning sensation to skin on lower legs.

    ACE levels fluctuate but average 110 - 150.

    Blood pressure on average is 150 / 78 - no treatment given

    I also take Nefopam Hydrochloride (Acupan) for pain but this drug is not on the list.

    Immobility, fatigue and constant pain have left me very depressed ad harbouring thoughts of suicide. My 15 year old granddaughter has lived with me since the death of my daughter 11 years ago and it is my hope that I will live long enough to see her settled in college and independent after which the only thing I have to look forward to is to end my own suffering.

    Reply

    IchikireiLV on Sep, 5, 2014:

    I was so sorry to read your comment, but glad I encountered it. PLEASE PLEASE don't ever think of taking your own life! I know what it is like to suffer. I injured myself 7 yrs ago, got a spinal implant that failed, compressed my spine, corroded and left me with heavy metal toxicity which caused adrenal failure, hypothyroid and many other serious health conditions. I have lived a life of chronic pain, fatigue and difficulty, so I know exactly where you are coming from! Some days I am so weak and have so much pain that I cannot get out of bed or care for myself. At times I try to puch myself to do the simplest things and my body is so frail I can barely catch my breath and feel like I gave to crawl back to my bed, dripping in sweat, dehydrated and defeated... but I still go on in hopes that there will be a better day. I ENCOURAGE YOU TO SEE A PAIN MANAGEMENT DR. MONTHLY FOR MEDICATIONS TO CONTROL YOUR PAIN! This alone will improve your daily life immensely! Pain will make you depressed! I also use Savella. It helps with Neuropathy pain AND DEPRESSION. Dont give up because doctors arent helping you enough. MAKE THEM! Its unacceptable that they are not following thru but I myself have experienced this many times.. Find another better, more compassionate Dr. Read Dr. reviews online, start with a primary care family dr, a pain dr and a rhuematologist for Sarcoidosis... make sure the Dr. is experienced with Sarcoidosis.. if not, find another one. I hope this helps you and gives you a direction to follow. Once your pain is controlled, things will be a lot better. Good luck and wishes of health and most of all HOPE and HAPPINESS 😄😄

    Reply

    Kath Nugent on Aug, 26, 2014:

    I was diagnosed with Lymphatic Sarcoidosis 15 years ago. After massive weight loss, a node in my neck the size of a small egg, and at the same time an
    area of my gum opened up were i had a tooth removed 20 years earlier, Sarcoid grew out of this opening !!it was like a piece of green string. My GP & Consultant tried to pull it out but failed,it was about an inch long. i was sent away with no further appointment, So i went to see my Dentist who seemed to know what it was and sent me to the Hospital Dentist who did a jaw bone Scraping and arranged for the node in neck to be removed for biopsy, both biopsy came back as Sarcoidosis. i was then x rayed and was found to have it in on my lungs as well. at this point i had active Sarcoidosis in my Lymphatic system, bone, lungs. However it as never been active in my lungs !!! it did however eat away the inside of my nose, it attacked my eyes i almost went blind, i lost my balance,it was in my brain.
    i was so tired, and after so many steroids i was having a bad reaction to them in various organs and was taken of them. i did recover from this as the Sarcoid went dormant. i have recently been diagnosed with a brain tumor and raised platelets. given that Sarcoidosis is next door to Cancer and that i feel absolutely wasted and week!!! i am feeling anxious about the outcome of more tests. But we all have to go sometime and i know there are people out there worse than me !!! i send you all love & light and hope we can all have the strength to help each other through whatever is thrown at us!! not easy by any means. Happy to answer any questions if it will help anyone Take care Kath Nugent

    Reply

  • From this study (7 months ago):

  • My diafram. Feels like its pushing on my lungs but they are clear to doctors check up.

    Diagnosed with fatty liver disease during this time due to bloodwork and echo on heart then abdominal ultrasound

    Does ra attack liver or is it causing infect ion on an organ white blood cell couny in all three labs were very high as well as sugar levels being slighty high

    Reply

  • From this study (7 months ago):

  • I just begsn tx for rs using safest meds possible but did not yolerste pills so we are doing injections once a week but since we started I developed abdom ook nal edema plus whole body especially feet which subsided ptior to msjor orgsn testing hestt kidney bloodwotk a nd liver ultra sound. Results were normsl all in but kidney workup. We are trying to get to third week of methotrexate tx becausr the last uri which my ra dr treated immediately with snyibiotics my ra pain seemed much better I just had abdominal swelling and pressure on lungs thrn and yhis time entire body swelled dr rulled out ra it was edrma order err d tests with bed rest feet up over weekend causing edema to go away prior to echo and ultra sound. Tests were normal so went to pulmonologist to get help breathing and they were sfraid to use antibiotics just like my primary dr brgore they know nothing about my ra drugs so how am I supposed to stop this from going inyo pneumonia?

    Reply

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More reviews for: Methotrexate, Shortness of breath

On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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