Methotrexate and Skin depigmentation - from FDA reports


Summary

Skin depigmentation is found among people who take Methotrexate, especially for people who are female, 40-49 old , have been taking the drug for 2 - 5 years, also take medication Humira, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 21 have Skin depigmentation. Find out below who they are, when they have Skin depigmentation and more.

What to expect?

If you take Methotrexate and have Skin depigmentation, find out what symptoms you could have in 1 year or longer.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,560 users)

Skin Depigmentation

Skin depigmentation (lightening of the skin) has been reported by people with high blood pressure, rheumatoid arthritis, pain, hepatitis c, depression (latest reports from 759 Skin depigmentation patients).

On Jan, 29, 2017

209,150 people reported to have side effects when taking Methotrexate.
Among them, 21 people (0.01%) have Skin Depigmentation


Number of reports submitted per year:

Could Methotrexate cause Skin depigmentation?

Time on Methotrexate when people have Skin Depigmentation *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Skin Depigmentation when taking Methotrexate *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Skin Depigmentation when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 20.0 %
  • 20-29: 0.0 %
  • 30-39: 20.0 %
  • 40-49: 33.33 %
  • 50-59: 20.0 %
  • 60+: 6.67 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (12 people, 57.14%)
  • Hypothyroidism (2 people, 9.52%)
  • Hypersensitivity (2 people, 9.52%)
  • High Blood Pressure (2 people, 9.52%)
  • Multiple Sclerosis (1 person, 4.76%)

Top co-used drugs for these people *:

  • Humira (8 people, 38.10%)
  • Prednisone (4 people, 19.05%)
  • Folic Acid (3 people, 14.29%)
  • Enbrel (3 people, 14.29%)
  • Cyclosporine (3 people, 14.29%)

Top other side effects for these people *:

  • Drug Ineffective (4 people, 19.05%)
  • Skin Exfoliation (3 people, 14.29%)
  • Rheumatoid Arthritis (3 people, 14.29%)
  • Rashes (3 people, 14.29%)
  • Itching (2 people, 9.52%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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