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Review: could Methotrexate cause Squamous cell cancer - mouth?

Summary: Squamous cell cancer - mouth could be caused by Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take Humira, and have Rheumatoid arthritis.

We study 129,658 people who have side effects while taking Methotrexate from FDA and social media. Among them, 5 have Squamous cell cancer - mouth. Find out below who they are, when they have Squamous cell cancer - mouth and more.

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Methotrexate

Methotrexate (latest outcomes from 130,985 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Squamous cell cancer - mouth

Squamous cell cancer - mouth (mouth cancer of a kind of epithelial cell) (latest reports from 3,525 patients) has been reported by people with multiple sclerosis, osteopenia, rheumatoid arthritis, osteoporosis, high blood pressure.

On Apr, 5, 2014: 129,615 people reported to have side effects when taking Methotrexate. Among them, 5 people (0.00%) have Squamous Cell Cancer - Mouth. They amount to 0.14% of all the 3,522 people who have Squamous Cell Cancer - Mouth on eHealthMe.

Trend of Squamous cell cancer - mouth in Methotrexate reports

Time on Methotrexate when people have Squamous cell cancer - mouth * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Squamous cell cancer - mouth0.00%0.00%50.00%0.00%0.00%50.00%0.00%

Gender of people who have Squamous cell cancer - mouth when taking Methotrexate * :

FemaleMale
Squamous cell cancer - mouth66.67%33.33%

Age of people who have Squamous cell cancer - mouth when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Squamous cell cancer - mouth0.00%0.00%0.00%0.00%0.00%20.00%20.00%60.00%

Severity of Squamous cell cancer - mouth when taking Methotrexate ** :

leastmoderateseveremost severe
Squamous cell cancer - mouth0.00%100.00%0.00%0.00%

How people recovered from Squamous cell cancer - mouth ** :

while on the drugafter off the drugnot yet
Squamous cell cancer - mouth100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (4 people, 80.00%)
  2. Blood cholesterol increased (1 people, 20.00%)
  3. Diabetes mellitus (1 people, 20.00%)
  4. Thyroid disorder (1 people, 20.00%)
  5. Arthritis (1 people, 20.00%)

Top co-used drugs for these people * :

  1. Humira (4 people, 80.00%)
  2. Remicade (3 people, 60.00%)
  3. Meloxicam (2 people, 40.00%)
  4. Fenofibrate (1 people, 20.00%)
  5. Glipizide (1 people, 20.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Methotrexate, Squamous cell cancer - mouth

You can also:

On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (9 hours ago):

  • my chest hurts so bad from coughing i cant take the pain. the coughing is so severe it causes me to lose control of my bladder. i have an awful headache from coughing so loud and so severe. i have been in bed for nearly a month I am so sick. i can hear my lungs breathing with my mouth closed it sounds so strange to hear my lungs making crackling noises outside of my chest.

    Reply

  • From this study (10 hours ago):

  • Sarcoidosis caused complete heart block. Pacemaker implanted in December 2009 but for the past two years I have had palpitations caused by around 3.7 million ectopic heartbeats per year.

    Sarcoidosis also in lungs and eyes. Extended use of Pred Forte caused development of cataracts, one of which has been removed and I am awaiting the second operation.

    Breathlessness is caused by lack of oxygen entering the bloodstream and my ongoing heart problems

    Rarely able to sleep properly due to pain, sleeping for about 20 minutes at a time when I become so exhausted that the pain can't keep me awake

    Muscle and joint pain have made me weak and clumsy.Pain is felt all over, from head to toes along with muscle cramps and intense burning sensation to skin on lower legs.

    ACE levels fluctuate but average 110 - 150.

    Blood pressure on average is 150 / 78 - no treatment given

    I also take Nefopam Hydrochloride (Acupan) for pain but this drug is not on the list.

    Immobility, fatigue and constant pain have left me very depressed ad harbouring thoughts of suicide. My 15 year old granddaughter has lived with me since the death of my daughter 11 years ago and it is my hope that I will live long enough to see her settled in college and independent after which the only thing I have to look forward to is to end my own suffering.

    Reply

  • From this study (2 days ago):

  • Trying to determine if the timing of these drugs- especially the weekly mtx- should be staggered during the day to ensure they are appropriately absorbed. Periodic seizures continue- about once a quarter.

    Reply

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- Methotrexate side effects

 

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- Squamous Cell Cancer - Mouth

 

 

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