Review: could Methotrexate cause Tooth Infection?


Summary

Tooth infection is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Rheumatoid arthritis . We study 191,458 people who have side effects while taking Methotrexate from FDA and social media. Among them, 786 have Tooth infection. Find out below who they are, when they have Tooth infection and more.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 205,730 users)

Tooth Infection

Tooth infection has been reported by people with rashes, itching, diarrhea, tooth abscess, nausea and vomiting (latest reports from 15,876 Tooth infection patients).

On Sep, 16, 2016

191,458 people reported to have side effects when taking Methotrexate.
Among them, 786 people (0.41%) have Tooth Infection


Number of reports submitted per year:

Could Methotrexate cause Tooth infection?

Time on Methotrexate when people have Tooth Infection *:

  • < 1 month: 6.25 %
  • 1 - 6 months: 9.38 %
  • 6 - 12 months: 3.12 %
  • 1 - 2 years: 31.25 %
  • 2 - 5 years: 31.25 %
  • 5 - 10 years: 9.38 %
  • 10+ years: 9.38 %

Gender of people who have Tooth Infection when taking Methotrexate *:

  • female: 81.4 %
  • male: 18.6 %

Age of people who have Tooth Infection when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.33 %
  • 10-19: 0.49 %
  • 20-29: 1.8 %
  • 30-39: 4.91 %
  • 40-49: 16.37 %
  • 50-59: 34.7 %
  • 60+: 41.41 %

Severity if Tooth Infection when taking Methotrexate **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

How people recovered from Tooth Infection **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (478 people, 60.81%)
  • Osteoporosis (59 people, 7.51%)
  • Psoriatic Arthropathy (56 people, 7.12%)
  • Pain (47 people, 5.98%)
  • Hypertension (42 people, 5.34%)

Top co-used drugs for these people *:

  • Enbrel (336 people, 42.75%)
  • Folic Acid (214 people, 27.23%)
  • Humira (162 people, 20.61%)
  • Prednisone (159 people, 20.23%)
  • Zometa (86 people, 10.94%)

Top other side effects for these people *:

  • Pain (124 people, 15.78%)
  • Arthralgia (117 people, 14.89%)
  • Sinusitis (101 people, 12.85%)
  • Fatigue (94 people, 11.96%)
  • Osteonecrosis Of Jaw (86 people, 10.94%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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