Review: could Methotrexate cause Tooth Infection?


Tooth infection is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Rheumatoid arthritis . We study 150,779 people who have side effects while taking Methotrexate from FDA and social media. Among them, 608 have Tooth infection. Find out below who they are, when they have Tooth infection and more.

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Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 160,929 users)

Tooth Infection

Tooth infection has been reported by people with breathing difficulty, rashes, abdominal pain upper, itching, diarrhea (latest reports from 12,647 Tooth infection patients).

On Aug, 29, 2016

150,779 people reported to have side effects when taking Methotrexate.
Among them, 608 people (0.4%) have Tooth Infection

Number of reports submitted per year:

Could Methotrexate cause Tooth infection?

Time on Methotrexate when people have Tooth Infection *:

  • < 1 month: 10.34 %
  • 1 - 6 months: 3.45 %
  • 6 - 12 months: 3.45 %
  • 1 - 2 years: 34.48 %
  • 2 - 5 years: 24.14 %
  • 5 - 10 years: 10.34 %
  • 10+ years: 13.79 %

Gender of people who have Tooth Infection when taking Methotrexate *:

  • female: 81.13 %
  • male: 18.87 %

Age of people who have Tooth Infection when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.22 %
  • 10-19: 0.43 %
  • 20-29: 1.52 %
  • 30-39: 4.34 %
  • 40-49: 15.84 %
  • 50-59: 36.88 %
  • 60+: 40.78 %

Severity if Tooth Infection when taking Methotrexate **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

How people recovered from Tooth Infection **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (349 people)
  • Osteoporosis (56 people)
  • Psoriatic Arthropathy (45 people)
  • Pain (38 people)
  • Systemic Lupus Erythematosus (37 people)

Top co-used drugs for these people *:

  • Enbrel (281 people)
  • Folic Acid (210 people)
  • Prednisone (157 people)
  • Humira (117 people)
  • Zometa (85 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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