Methotrexate and Venoocclusive liver disease - from FDA reports
Venoocclusive liver disease is found among people who take Methotrexate, especially for people who are male, 2-9 old , have been taking the drug for < 1 month, also take medication Cyclophosphamide, and have Stem cell transplant. This review analyzes which people have Venoocclusive liver disease with Methotrexate. It is created by eHealthMe based on reports of 223,372 people who have side effects when taking Methotrexate from FDA, and is updated regularly.
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On May, 13, 2017
223,372 people reported to have side effects when taking Methotrexate.
Among them, 393 people (0.18%) have Venoocclusive Liver Disease
Number of reports submitted per year:
Time on Methotrexate when people have Venoocclusive Liver Disease *:
- < 1 month: 90.72 %
- 1 - 6 months: 6.19 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 3.09 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Venoocclusive Liver Disease when taking Methotrexate *:
- female: 39.88 %
- male: 60.12 %
Age of people who have Venoocclusive Liver Disease when taking Methotrexate *:
- 0-1: 6.95 %
- 2-9: 24.5 %
- 10-19: 12.25 %
- 20-29: 14.9 %
- 30-39: 5.63 %
- 40-49: 9.6 %
- 50-59: 15.23 %
- 60+: 10.93 %
Top conditions involved for these people *:
- Stem Cell Transplant (76 people, 19.34%)
- Bone Marrow Conditioning Regimen (53 people, 13.49%)
- Graft Versus Host Disease (50 people, 12.72%)
- Acute Lymphocytic Leukemia (all) (50 people, 12.72%)
- Preventive Health Care (46 people, 11.70%)
Top co-used drugs for these people *:
- Cyclophosphamide (125 people, 31.81%)
- Cyclosporine (114 people, 29.01%)
- Tacrolimus (82 people, 20.87%)
- Prograf (69 people, 17.56%)
- Busulfan (51 people, 12.98%)
Top other side effects for these people *:
- Fever (53 people, 13.49%)
- Ascites (50 people, 12.72%)
- Graft Versus Host Disease (46 people, 11.70%)
- Thrombocytopenia (44 people, 11.20%)
- Hepatomegaly (44 people, 11.20%)
* Approximation only. Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 226,881 users)
Venoocclusive Liver Disease
Venoocclusive liver disease (small veins in the liver are obstructed) has been reported by people with acute myeloid leukaemia, stem cell transplant, bone marrow conditioning regimen, preventive health care, acute lymphocytic leukemia (all) (latest reports from 2,180 Venoocclusive liver disease patients).
Browse all side effects of Methotrexatea b c d e f g h i j k l m n o p q r s t u v w x y z
Drugs that are associated with Venoocclusive liver diseaseVenoocclusive liver disease
Could your condition cause Venoocclusive liver diseaseVenoocclusive liver disease
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This is for my father. Shortly after starting methotrexate injections and cortisone for Rheumatoid arthritis my father started having language difficulties and now has dementia. He was diagnosed with Pick's disease. Could it be caused by these drugs? He is still taking them.
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