Review: could Methotrexate cause Venoocclusive liver disease?
This is a review of Venoocclusive liver disease by studying 124,856 people who take Methotrexate. We analyze: the time on Methotrexate when people have Venoocclusive liver disease, gender and age of these people, the severity of Venoocclusive liver disease, how they recovered, and common conditions and drugs used besides Methotrexate. The review is created by eHealthMe based on reports from FDA and social media, and is updated regularly.
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Methotrexate (latest outcomes from 130,928 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis, psoriatic arthritis. Commonly reported side effects of Methotrexate include fever, injection site pain, joint pain, nausea, nausea aggravated.
Venoocclusive liver disease
Venoocclusive liver disease (small veins in the liver are obstructed) (latest reports from 7,584 patients) has been reported by people with acute myeloid leukaemia, stem cell transplant, prophylaxis against graft versus host disease, bone marrow conditioning regimen, bone marrow transplant.
On Mar, 9, 2014: 124,856 people reported to have side effects when taking Methotrexate. Among them, 303 people (0.24%) have Venoocclusive Liver Disease. They amount to 4.00% of all the 7,580 people who have Venoocclusive Liver Disease.
Time on Methotrexate when people have Venoocclusive liver disease * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Venoocclusive liver disease||92.68%||3.66%||0.00%||3.66%||0.00%||0.00%||0.00% |
Gender of people who have Venoocclusive liver disease when taking Methotrexate * :
|Venoocclusive liver disease||42.81%||57.19% |
Age of people who have Venoocclusive liver disease when taking Methotrexate * :
|Venoocclusive liver disease||5.88%||24.31%||14.12%||16.47%||4.31%||10.98%||19.22%||4.71% |
Severity of Venoocclusive liver disease when taking Methotrexate ** :
How people recovered from Venoocclusive liver disease ** :
Top conditions involved for these people * :
- Bone marrow conditioning regimen (46 people, 15.18%)
- Graft versus host disease (46 people, 15.18%)
- Prophylaxis (40 people, 13.20%)
- Bone marrow transplant (38 people, 12.54%)
- Acute lymphocytic leukaemia (24 people, 7.92%)
Top co-used drugs for these people * :
- Cyclosporine (132 people, 43.56%)
- Cyclophosphamide (126 people, 41.58%)
- Tacrolimus (91 people, 30.03%)
- Prograf (66 people, 21.78%)
- Acyclovir (52 people, 17.16%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Related topic: Methotrexate, Venoocclusive liver disease
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