Review: could Methotrexate cause Venoocclusive liver disease?
Summary: Venoocclusive liver disease is found among people who take Methotrexate, especially for people who are male, 2-9 old, have been taking the drug for < 1 month, also take medication Cyclosporine, and have Bone marrow conditioning regimen.
We study 129,908 people who have side effects while taking Methotrexate from FDA and social media. Among them, 303 have Venoocclusive liver disease. Find out below who they are, when they have Venoocclusive liver disease and more.
You are not alone: join a support group for people who take Methotrexate and have Venoocclusive liver disease >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,250 Methotrexate users)
Venoocclusive liver disease
Venoocclusive liver disease (small veins in the liver are obstructed) has been reported by people with acute myeloid leukaemia, stem cell transplant, prophylaxis against graft versus host disease, bone marrow conditioning regimen, bone marrow transplant. (latest reports from 1,563 Venoocclusive liver disease patients)
On Mar, 4, 2015: 129,897 people reported to have side effects when taking Methotrexate. Among them, 303 people (0.23%) have Venoocclusive Liver Disease.
Time on Methotrexate when people have Venoocclusive liver disease * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Venoocclusive liver disease||92.68%||3.66%||0.00%||3.66%||0.00%||0.00%||0.00% |
Gender of people who have Venoocclusive liver disease when taking Methotrexate * :
|Venoocclusive liver disease||42.81%||57.19% |
Age of people who have Venoocclusive liver disease when taking Methotrexate * :
|Venoocclusive liver disease||5.88%||24.31%||14.12%||16.47%||4.31%||10.98%||19.22%||4.71% |
Severity of Venoocclusive liver disease when taking Methotrexate ** :
How people recovered from Venoocclusive liver disease ** :
Top conditions involved for these people * :
- Bone marrow conditioning regimen (46 people, 15.18%)
- Graft versus host disease (46 people, 15.18%)
- Prophylaxis (40 people, 13.20%)
- Bone marrow transplant (38 people, 12.54%)
- Acute lymphocytic leukaemia (24 people, 7.92%)
Top co-used drugs for these people * :
- Cyclosporine (132 people, 43.56%)
- Cyclophosphamide (126 people, 41.58%)
- Tacrolimus (91 people, 30.03%)
- Prograf (66 people, 21.78%)
- Acyclovir (52 people, 17.16%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Get connected: join our support group of methotrexate and venoocclusive liver disease on
Do you have Venoocclusive Liver Disease while taking Methotrexate?
You are not alone! Join a mobile support group on :
- support group for people who take Methotrexate and have Venoocclusive Liver Disease
- support group for people who take Methotrexate
- support group for people who have Venoocclusive Liver Disease
Drugs in real world that are associated with:
Could your condition cause:
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- A study of drug interactions between Fluoxetine, Omeprazole, Prednisone, Folic Acid, Enbrel, Methotrexate for a 56-year old woman with Depression, Chest Tightness Or Pressure, Rheumatoid Arthritis. The patient has Tremor
- A study of drug interactions between Lumigan, Doxazosin Mesylate, Ramipril, Diazepam, Prednisolone, Paracetamol, Tramadol, Folic Acid, Methotrexate for a 66-year old man with Pressure Sore, Blood Pressure Increased, Anxiety Disorder Due To A General Medical Condition, Rheumatoid Arthritis, Lung Surgery. The patient has Oral Discharge
- A study of drug interactions between Prednisone, Plaquenil, Methotrexate, Orencia for a 60-year old woman with Rheumatoid Arthritis. The patient has Appendicitis Perforated
- A study of drug interactions between Folic Acid, Paracetamol, Naproxen, Tramadol, Methotrexate, Enbrel for a 47-year old man with Rheumatoid Arthritis. The patient has Premature Ejaculation
Recent Methotrexate related drug comparison:
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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