Review: could Methotrexate cause Venoocclusive liver disease?
Summary: Venoocclusive liver disease could be caused by Methotrexate, especially for people who are male, 2-9 old, have been taking the drug for < 1 month, also take Cyclosporine, and have Bone marrow conditioning regimen.
We study 129,668 people who have side effects while taking Methotrexate from FDA and social media. Among them, 303 have Venoocclusive liver disease. Find out below who they are, when they have Venoocclusive liver disease and more.
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Methotrexate (latest outcomes from 130,985 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.
Venoocclusive liver disease
Venoocclusive liver disease (small veins in the liver are obstructed) (latest reports from 7,639 patients) has been reported by people with acute myeloid leukaemia, stem cell transplant, prophylaxis against graft versus host disease, bone marrow conditioning regimen, bone marrow transplant.
On Apr, 9, 2014: 129,615 people reported to have side effects when taking Methotrexate. Among them, 303 people (0.23%) have Venoocclusive Liver Disease. They amount to 3.98% of all the 7,619 people who have Venoocclusive Liver Disease on eHealthMe.
Time on Methotrexate when people have Venoocclusive liver disease * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Venoocclusive liver disease||92.68%||3.66%||0.00%||3.66%||0.00%||0.00%||0.00% |
Gender of people who have Venoocclusive liver disease when taking Methotrexate * :
|Venoocclusive liver disease||42.81%||57.19% |
Age of people who have Venoocclusive liver disease when taking Methotrexate * :
|Venoocclusive liver disease||5.88%||24.31%||14.12%||16.47%||4.31%||10.98%||19.22%||4.71% |
Severity of Venoocclusive liver disease when taking Methotrexate ** :
How people recovered from Venoocclusive liver disease ** :
Top conditions involved for these people * :
- Bone marrow conditioning regimen (46 people, 15.18%)
- Graft versus host disease (46 people, 15.18%)
- Prophylaxis (40 people, 13.20%)
- Bone marrow transplant (38 people, 12.54%)
- Acute lymphocytic leukaemia (24 people, 7.92%)
Top co-used drugs for these people * :
- Cyclosporine (132 people, 43.56%)
- Cyclophosphamide (126 people, 41.58%)
- Tacrolimus (91 people, 30.03%)
- Prograf (66 people, 21.78%)
- Acyclovir (52 people, 17.16%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
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Related topic: Methotrexate, Venoocclusive liver disease
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