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Home > Methotrexate > Venoocclusive liver disease > Methotrexate and Venoocclusive liver disease

Review: could Methotrexate cause Venoocclusive liver disease?

Summary: Venoocclusive liver disease is found among people who take Methotrexate, especially for people who are male, 2-9 old, have been taking the drug for < 1 month, also take medication Cyclosporine, and have Bone marrow conditioning regimen.

We study 129,841 people who have side effects while taking Methotrexate from FDA and social media. Among them, 303 have Venoocclusive liver disease. Find out below who they are, when they have Venoocclusive liver disease and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Venoocclusive liver disease >>>

Methotrexate

Methotrexate (latest outcomes from 131,185 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Trend of methotrexate reports

Venoocclusive liver disease

Venoocclusive liver disease (small veins in the liver are obstructed) (latest reports from 7,761 patients) has been reported by people with acute myeloid leukaemia, stem cell transplant, prophylaxis against graft versus host disease, bone marrow conditioning regimen, bone marrow transplant.

On Nov, 24, 2014: 129,841 people reported to have side effects when taking Methotrexate. Among them, 303 people (0.23%) have Venoocclusive Liver Disease.

Trend of Venoocclusive liver disease in Methotrexate reports

Time on Methotrexate when people have Venoocclusive liver disease * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Venoocclusive liver disease92.68%3.66%0.00%3.66%0.00%0.00%0.00%

Gender of people who have Venoocclusive liver disease when taking Methotrexate * :

FemaleMale
Venoocclusive liver disease42.81%57.19%

Age of people who have Venoocclusive liver disease when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Venoocclusive liver disease5.88%24.31%14.12%16.47%4.31%10.98%19.22%4.71%

Severity of Venoocclusive liver disease when taking Methotrexate ** :

n/a

How people recovered from Venoocclusive liver disease ** :

n/a

Top conditions involved for these people * :

  1. Bone marrow conditioning regimen (46 people, 15.18%)
  2. Graft versus host disease (46 people, 15.18%)
  3. Prophylaxis (40 people, 13.20%)
  4. Bone marrow transplant (38 people, 12.54%)
  5. Acute lymphocytic leukaemia (24 people, 7.92%)

Top co-used drugs for these people * :

  1. Cyclosporine (132 people, 43.56%)
  2. Cyclophosphamide (126 people, 41.58%)
  3. Tacrolimus (91 people, 30.03%)
  4. Prograf (66 people, 21.78%)
  5. Acyclovir (52 people, 17.16%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Venoocclusive Liver Disease while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Venoocclusive Liver Disease
- support group for people who take Methotrexate
- support group for people who have Venoocclusive Liver Disease

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