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Review: could Methotrexate cause Venoocclusive liver disease?

We study 129,821 people who have side effects while taking Methotrexate from FDA and social media. Among them, 303 have Venoocclusive liver disease. Find out below who they are, when they have Venoocclusive liver disease and more.

Get connected: join a mobile support group for people who take Methotrexate and have Venoocclusive liver disease >>>

Methotrexate

Methotrexate (latest outcomes from 131,137 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Venoocclusive liver disease

Venoocclusive liver disease (small veins in the liver are obstructed) (latest reports from 7,759 patients) has been reported by people with acute myeloid leukaemia, stem cell transplant, prophylaxis against graft versus host disease, bone marrow conditioning regimen, bone marrow transplant.

On Oct, 24, 2014: 129,821 people reported to have side effects when taking Methotrexate. Among them, 303 people (0.23%) have Venoocclusive Liver Disease.

Trend of Venoocclusive liver disease in Methotrexate reports

Time on Methotrexate when people have Venoocclusive liver disease * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Venoocclusive liver disease92.68%3.66%0.00%3.66%0.00%0.00%0.00%

Gender of people who have Venoocclusive liver disease when taking Methotrexate * :

FemaleMale
Venoocclusive liver disease42.81%57.19%

Age of people who have Venoocclusive liver disease when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Venoocclusive liver disease5.88%24.31%14.12%16.47%4.31%10.98%19.22%4.71%

Severity of Venoocclusive liver disease when taking Methotrexate ** :

n/a

How people recovered from Venoocclusive liver disease ** :

n/a

Top conditions involved for these people * :

  1. Bone marrow conditioning regimen (46 people, 15.18%)
  2. Graft versus host disease (46 people, 15.18%)
  3. Prophylaxis (40 people, 13.20%)
  4. Bone marrow transplant (38 people, 12.54%)
  5. Acute lymphocytic leukaemia (24 people, 7.92%)

Top co-used drugs for these people * :

  1. Cyclosporine (132 people, 43.56%)
  2. Cyclophosphamide (126 people, 41.58%)
  3. Tacrolimus (91 people, 30.03%)
  4. Prograf (66 people, 21.78%)
  5. Acyclovir (52 people, 17.16%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Venoocclusive Liver Disease while taking Methotrexate?

Get connected! Join a mobile support group:
- group for people who take Methotrexate and have Venoocclusive Liver Disease
- group for people who take Methotrexate
- group for people who have Venoocclusive Liver Disease

Comments from related studies:

  • From this study (18 hours ago):

  • All lesions necrosis
    Painful granulomas
    I live in chronic pain and fatigue

    Reply

    Lisa on Sep, 4, 2014:

    Female 55 I have bechets. Diagnosed at 39. I take every medication on that list except I dropped methotrexate. I worse since I dropped it. And I have every symptom including ganglion cyst which needs to be surgically removed to the throat lesion. I can barely function. The only 5hing I dont have is the allergic cough. I did have mrsa phenomia once. Oh most recently plursey. I have been ivig dependent for 13 years.

    Reply

  • From this study (1 week ago):

  • take subque due to illeostomy on weekly basis

    Reply

  • From this study (1 week ago):

  • I recently quit taking all meds due to loss of insurance coverage. I have been having symptoms for a week that seem to only get worse

    Reply

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On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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