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Review: could Methotrexate cause Vomiting (Nausea and vomiting)?





Summary: Vomiting is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Folic acid, and have Rheumatoid arthritis.

We study 129,858 people who have side effects while taking Methotrexate from FDA and social media. Among them, 3,179 have Vomiting. Find out below who they are, when they have Vomiting and more.

You are not alone: join a mobile support group for people who take Methotrexate and have Vomiting >>>

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (view latest outcomes from 131,201 users)

Vomiting

Vomiting has been reported by people with high blood pressure, pain, type 2 diabetes, depression, multiple sclerosis.(view latest reports from 179,280 patients)

On Nov, 25, 2014: 129,841 people reported to have side effects when taking Methotrexate. Among them, 3,866 people (2.98%) have Vomiting.

Trend of Vomiting in Methotrexate reports

Time on Methotrexate when people have Vomiting * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Vomiting38.73%20.35%9.63%10.72%13.79%4.38%2.41%

Gender of people who have Vomiting when taking Methotrexate * :

FemaleMale
Vomiting73.60%26.40%

Age of people who have Vomiting when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Vomiting0.58%8.39%11.80%4.52%9.15%12.82%20.69%32.05%

Severity of Vomiting when taking Methotrexate ** :

leastmoderateseveremost severe
Vomiting7.69%46.15%38.46%7.69%

How people recovered from Vomiting ** :

while on the drugafter off the drugnot yet
Vomiting0.00%12.50%87.50%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (1,601 people, 41.41%)
  2. Pain (240 people, 6.21%)
  3. Prophylaxis (172 people, 4.45%)
  4. Hypertension (167 people, 4.32%)
  5. Osteoporosis (146 people, 3.78%)

Top co-used drugs for these people * :

  1. Folic acid (1,123 people, 29.05%)
  2. Humira (751 people, 19.43%)
  3. Prednisone (724 people, 18.73%)
  4. Enbrel (607 people, 15.70%)
  5. Remicade (570 people, 14.74%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Vomiting while taking Methotrexate?

You are not alone! Join a mobile support group:
- support group for people who take Methotrexate and have Vomiting
- support group for people who take Methotrexate
- support group for people who have Vomiting

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Can you answer these questions (Ask a question):

  • Is vomiting all liquids common while taking morphine
    I Recently started taking 6mg of Hydro-Morphine per day for pain. Every time i take the drug i vomit up any liquids I drink. i fell just fine without anything in my stomach but as soon as i eat or drink I instantly become nauseated and vomit everything. It is hard not to drink because the drug is making me very thirsty. So i try to drink and my body rejects it over and over again.. this goes on for hours (3-5)because i am sooo thirsty that I can not stop drinking.
    Reply
  • Hlab27 antigen and unexplained scratches caused by accutane
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) unexplained scratches in same location, forearms, lower thigh (by knee) fingers. Scratches always are in a line with a break in the line. When a woman hits menopause hormones cease and when this happens the path that Accutane takes to cease sebaceous gland function, skin proliferation ceases. Therefore, my friends the HLA B27 (abnormal antigen targeted for skin proliferation does not know where to go so it randomly attacks whatever organ it chooses. Accutane if I remember correctly and I do have proof, permanently alters DNA. There is no other way orally ingesting a retinolic acid it could control skin, hormonal cesessation. I have only been diagnosed thus far with psoriatic arthritis with no other explanations for these other symptoms. I wonder why this is and I also wonder why dermatologists refuse to take a biopsy of my skin to rule out cell skin proliferation dysfunction. What will this damaging drug attack next. Do no be fooled by Dr.s who tell you that you took this drug so long ago how could this be. Well folks, it is because it has already changed your DNA to the HLAB27 antigen. My question also is, what was supposed to be where this abnormal DNA antigen is and how come this antigen only shows up at menopause. My disease (autoimmune) is progressive) and has already attacked nervous, muscle, skin, joints etc. Interesting
    Reply
  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?
    Reply
  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area... (2 answers)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms seem more noticeable in the evening. If I shower in a warm shower the symptoms will vanish for a time.. All my mammograms have been normal and never miss any but it has me very worried. I check my breasts often for lumps. From time to time it also seems like I have tenderness along the sternum on that side. I have rhematoid arthritis as well as was recently told I have osteoporosis. I had a thoracic x-ray and they can see loss of bone density and some vertebrae degeneration. Take methotrexate each week and folic acid every day....Any ideas out there???? Thanks
    Reply
  • My dr. prescribed me phergan. how common is weight gain on this drug?
    A Dr. prescribed me Phenergan and Potassium CL ER today. I read online that Phenergan can cause weight gain. Have any of you been on Phenergan, and if so have you experiences any weight gain or other symptoms I should be made aware of? Thank you in advance.
    Reply

More questions for: Methotrexate, Vomiting

You may be interested at these reviews (Write a review):

  • Nausea and vomiting while taking savella
    I have been on Savella for 6 months now and the nausea has increased with time and now I also have vomiting daily along with occasional diarrhea. I am currently weaning off of the Savella, cutting the dosage in half for two weeks and then one pill every other day for two weeks, following my dr.'s instructions. I have three weeks total left and still have the nausea and vomiting but hopeful that these will start to go away soon. Anyone else who has weaned off of it- how long until your symptoms subsided?
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  • Farxiga ? problems, stomach, smell, taste
    I have been on Farxiga for 2 months. First, I was on Farxiga 5mg, About 6 weeks ago changed to 10 mg, about same time I noticed my coffee smelled different and bad, kept on a week and asked my wife. Changed coffee brand twice. It got worse, began to taste it. For the last week I can smell it in my food, anything fresh out of microwave. Now I smell it in my bowel movement. I called Doctor earlier in week reported. He wants to wait about a week and call back if persists. I am a diabetic and first few days this helped. Doctor reduced my insulin and got me off glimepiride and my Sugar readings have been higher since such as 175-200. This is my only medicine change close to time period. Please respond with help or if you experience similar problems.
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  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
    Reply
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
    Reply
  • Poisened by fenofibrate
    it started in Apr. 2013. I would eat and get sick to my stomach. I would have severe shooting pains in my stomach area. My bowels were loose and would stay that way. Or at times I would just be nauseated for no apparent reason. My mouth got dry and I began having dizzy spells. Those last two symptoms mostly went away except for the dizziness which would only happen if I bent over. By July it was hard to look at food at all. This went on for an entire year, every day. The VA, which was taking care of me, diagnosed me with a bad gall bladder. It was finally taken out in Sept. Unfortunately it did me no good.

    On March 20, 2014, I took myself off this medication. Five days later the symptoms started to lift.
    Reply

More reviews for: Methotrexate, Vomiting

Comments from related drug studies (Check your drugs):

  • I have had insomnia off and on all my life until I turned 40 and the I was diagnosed with Psoriatic Arthritis and I was tired all the time and I was sleeping a lot for me and it was good to be able to sleep. The doctor put me on Methotrexate and Enbrel and I could still sleep not as much as before ...
    Reply
  • severe nausea and vomiting when take aleve for arthritus/joint pain, no longer take aleve, take advil instead. never experienced nausea and vomiting while taking wellbutrin and occaisionally taking advil for pain
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  • Generally happens every couple of mnths has now moved to mnthly and las two episodes were within 2 weeks of each other. Oct 12-13& oct31-nov 1. I believe pain to be mittleschmirtz the hot flashes and vomiting just started within the last year.
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  • I find I can read something but have a difficult time relating what I have just read to another person. Although I understand what I have read, I just seem to have great difficulty putting it into words to relate
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  • I am wondering if my mother's 2 years of taking Methatrexate about 3 years ago, could be causing a thyroid problem that is making her back and skeletal structure be in severe pain. Also her dementia is worsening
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More related studies for: Methotrexate, Vomiting

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