Methotrexate and Weight gain - from FDA reports


Summary

Weight gain is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis. This review analyzes which people have Weight gain with Methotrexate. It is created by eHealthMe based on reports of 223,372 people who have side effects when taking Methotrexate from FDA, and is updated regularly.

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On May, 15, 2017

223,372 people reported to have side effects when taking Methotrexate.
Among them, 2,875 people (1.29%) have Weight Gain


Number of reports submitted per year:

Could Methotrexate cause Weight gain?

Time on Methotrexate when people have Weight Gain *:

  • < 1 month: 42.34 %
  • 1 - 6 months: 15.33 %
  • 6 - 12 months: 5.11 %
  • 1 - 2 years: 13.87 %
  • 2 - 5 years: 15.33 %
  • 5 - 10 years: 3.65 %
  • 10+ years: 4.38 %

Gender of people who have Weight Gain when taking Methotrexate *:

  • female: 80.75 %
  • male: 19.25 %

Age of people who have Weight Gain when taking Methotrexate *:

  • 0-1: 0.18 %
  • 2-9: 2.02 %
  • 10-19: 2.89 %
  • 20-29: 4.03 %
  • 30-39: 9.03 %
  • 40-49: 18.11 %
  • 50-59: 29.81 %
  • 60+: 33.93 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (1,711 people, 59.51%)
  • Pain (234 people, 8.14%)
  • High Blood Pressure (189 people, 6.57%)
  • Psoriatic Arthropathy (159 people, 5.53%)
  • Depression (121 people, 4.21%)

Top co-used drugs for these people *:

  • Enbrel (779 people, 27.10%)
  • Humira (570 people, 19.83%)
  • Folic Acid (566 people, 19.69%)
  • Prednisone (471 people, 16.38%)
  • Actemra (461 people, 16.03%)

Top other side effects for these people *:

  • Joint Pain (607 people, 21.11%)
  • Pain (510 people, 17.74%)
  • Fatigue (457 people, 15.90%)
  • Drug Ineffective (407 people, 14.16%)
  • High Blood Pressure (363 people, 12.63%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Weight gain when taking Methotrexate?

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 226,881 users)

Weight Gain

Weight gain has been reported by people with depression, rheumatoid arthritis, high blood pressure, pain, multiple sclerosis (latest reports from 125,241 Weight gain patients).

Browse all side effects of Methotrexate

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Drugs that are associated with Weight gain

Weight gain

Could your condition cause Weight gain

Weight gain

Related studies

What would happen?

Forecast new side effects and undetected conditions when you take Methotrexate and have Weight gain.

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