Methotrexate and Weight gain - from FDA reports


Summary

Weight gain is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Enbrel, and have Rheumatoid arthritis . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 2,596 have Weight gain. Find out below who they are, when they have Weight gain and more.

What to expect?

If you take Methotrexate and have Weight gain, find out what symptoms you could have in 1 year or longer.

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Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,557 users)

Weight Gain

Weight gain has been reported by people with depression, high blood pressure, rheumatoid arthritis, multiple sclerosis, bipolar disorder (latest reports from 118,286 Weight gain patients).

On Jan, 29, 2017

209,150 people reported to have side effects when taking Methotrexate.
Among them, 2,596 people (1.24%) have Weight Gain


Number of reports submitted per year:

Could Methotrexate cause Weight gain?

Time on Methotrexate when people have Weight Gain *:

  • < 1 month: 45.67 %
  • 1 - 6 months: 17.32 %
  • 6 - 12 months: 5.51 %
  • 1 - 2 years: 12.6 %
  • 2 - 5 years: 11.02 %
  • 5 - 10 years: 3.94 %
  • 10+ years: 3.94 %

Gender of people who have Weight Gain when taking Methotrexate *:

  • female: 80.63 %
  • male: 19.37 %

Age of people who have Weight Gain when taking Methotrexate *:

  • 0-1: 0.2 %
  • 2-9: 2.16 %
  • 10-19: 3.2 %
  • 20-29: 4.08 %
  • 30-39: 8.95 %
  • 40-49: 18.64 %
  • 50-59: 30.1 %
  • 60+: 32.66 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (1,488 people, 57.32%)
  • Pain (217 people, 8.36%)
  • High Blood Pressure (177 people, 6.82%)
  • Psoriatic Arthropathy (144 people, 5.55%)
  • Depression (111 people, 4.28%)

Top co-used drugs for these people *:

  • Enbrel (733 people, 28.24%)
  • Folic Acid (565 people, 21.76%)
  • Humira (528 people, 20.34%)
  • Prednisone (471 people, 18.14%)
  • Actemra (363 people, 13.98%)

Top other side effects for these people *:

  • Joint Pain (518 people, 19.95%)
  • Pain (436 people, 16.80%)
  • Fatigue (396 people, 15.25%)
  • Drug Ineffective (321 people, 12.37%)
  • Headache (297 people, 11.44%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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