Review: could Methotrexate cause Weight gain?
(By eHealthMe on Mar, 6, 2014)
Severity ratings: 2.4/4
On a scale of 1 to 4: 1=least, 2=moderate, 3=severe, 4=most severe
We study 124,856 people who take Methotrexate. Among them, 1,301 have Weight gain. See who they are, when they have Weight gain and more. This review is based on reports from FDA and social media, and is updated regularly.
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Methotrexate (latest outcomes from 130,928 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis, psoriatic arthritis. Commonly reported side effects of Methotrexate include fever, injection site pain, joint pain, nausea, nausea aggravated.
Weight gain (latest reports from 510,411 patients) has been reported by people with depression, high blood pressure, bipolar disorder, pain, acupuncture and pain.
On Mar, 6, 2014: 124,856 people reported to have side effects when taking Methotrexate. Among them, 1,301 people (1.04%) have Weight Gain.
Time on Methotrexate when people have Weight gain * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Weight gain||47.71%||20.18%||4.59%||11.93%||10.09%||3.67%||1.83% |
Gender of people who have Weight gain when taking Methotrexate * :
|Weight gain||80.57%||19.43% |
Age of people who have Weight gain when taking Methotrexate * :
|Weight gain||0.27%||3.30%||4.81%||4.90%||11.41%||19.61%||27.54%||28.16% |
Severity of Weight gain when taking Methotrexate ** :
|least||moderate||severe||most severe |
|Weight gain||9.09%||54.55%||27.27%||9.09% |
How people recovered from Weight gain ** :
|while on the drug||after off the drug||not yet |
|Weight gain||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Rheumatoid arthritis (662 people, 50.88%)
- Pain (140 people, 10.76%)
- Hypertension (86 people, 6.61%)
- Vitamin supplementation (63 people, 4.84%)
- Arthritis (57 people, 4.38%)
Top co-used drugs for these people * :
- Folic acid (438 people, 33.67%)
- Enbrel (437 people, 33.59%)
- Prednisone (361 people, 27.75%)
- Humira (335 people, 25.75%)
- Omeprazole (120 people, 9.22%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Related topic: Methotrexate, Weight gain
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On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
What is Methotrexate used for and how effective is it:
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From this study (2 months ago):
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I was diagnosed with Still's disease late october this year and am struggling with the side effects of the disease and how much it has changed my life.
From this study (4 years ago):
The abnormal dreams & mild hallucinations came only after starting the methylprednisolone a few days ago. They happen primarily when I am sleeping. I woke up last night with very unusual dreams & head/brain pain, and was quite concerned. I had taken 1 methylprednisolone & 1 cymbalta before bed. Earlier in the day, I had taken 2 methylprednisolone & 2 tramadol before a nap, and had similar, though not as severe issues. Trying to figure out what the interaction problem is. I did not take the muscle relaxant (cyclopenzaprine) before bed since I started the cortico steroid pack.
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Recent related drug studies:
- A study of drug interactions between Liothyronine Sodium, Synthroid, Folic Acid, Plaquenil, Methotrexate for a patient with Thyroid Disorder, Rheumatoid Arthritis. The patient has Weight Increased, Heart Rate Increased
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