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Review: could Methotrexate cause Weight gain (Weight increased)?

We study 129,775 people who have side effects while taking Methotrexate from FDA and social media. Among them, 1,304 have Weight gain. Find out below who they are, when they have Weight gain and more.

Get connected: join a mobile support group for people who take Methotrexate and have Weight gain >>>

Methotrexate

Methotrexate (latest outcomes from 131,137 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Weight gain

Weight gain (latest reports from 527,553 patients) has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol.

On Sep, 15, 2014: 129,775 people reported to have side effects when taking Methotrexate. Among them, 1,304 people (1.00%) have Weight Gain.

Trend of Weight gain in Methotrexate reports

Time on Methotrexate when people have Weight gain * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Weight gain47.32%20.54%4.46%12.50%9.82%3.57%1.79%

Gender of people who have Weight gain when taking Methotrexate * :

FemaleMale
Weight gain80.61%19.39%

Age of people who have Weight gain when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Weight gain0.27%3.29%4.80%4.89%11.47%19.64%27.56%28.09%

Severity of Weight gain when taking Methotrexate ** :

leastmoderateseveremost severe
Weight gain7.14%50.00%28.57%14.29%

How people recovered from Weight gain ** :

while on the drugafter off the drugnot yet
Weight gain0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (663 people, 50.84%)
  2. Pain (140 people, 10.74%)
  3. Hypertension (86 people, 6.60%)
  4. Vitamin supplementation (63 people, 4.83%)
  5. Psoriatic arthropathy (58 people, 4.45%)

Top co-used drugs for these people * :

  1. Folic acid (440 people, 33.74%)
  2. Enbrel (437 people, 33.51%)
  3. Prednisone (362 people, 27.76%)
  4. Humira (335 people, 25.69%)
  5. Omeprazole (120 people, 9.20%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Weight Gain while taking Methotrexate?

Get connected! Join a mobile support group:
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Comments from related studies:

  • From this study (4 days ago):

  • Took synthroid after birth of daugther, 12 years ago. Eventually came off synthroid while takine kelp and selenium. Joint aches and pains, especially knees and elbows. TSH 4.22, which has doubled since starting methotrexate.

    Reply

  • From this study (4 months ago):

  • The abnormal dreams & mild hallucinations came only after starting the methylprednisolone a few days ago. They happen primarily when I am sleeping. I woke up last night with very unusual dreams & head/brain pain, and was quite concerned. I had taken 1 methylprednisolone & 1 cymbalta before bed. Earlier in the day, I had taken 2 methylprednisolone & 2 tramadol before a nap, and had similar, though not as severe issues. Trying to figure out what the interaction problem is. I did not take the muscle relaxant (cyclopenzaprine) before bed since I started the cortico steroid pack.

    Reply

    britsarmymom on Apr, 26, 2014:

    Mother just survived near brush with respiratory arrest. Hallucinated at night on Tramadol, argumentative with RN who reported her to MD. He planned to ADD Seroquel 25 mg to Tramadol, Neurontin, Remeron and Ativan in rehab facility. She declined Tramadol and Seroquel and was still so sedated her pulse ox went down to 84 with long periods of apnea and need for constant obs with frequent rousing for airway. MAJOR struggle with RN to get 02 and MD agreed to no more Tramodol at night and absolutely no Seroquel. How many elderly are lost this way?

    Reply

  • From this study (8 months ago):

  • Heart rate only increases after taking Plaquenil dose and then returns to normal a while later. I have also noticed weight gain since I started on plaquenil.

    Reply

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More reviews for: Methotrexate, Weight gain

On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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