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Review: could Methotrexate cause Weight gain?

Summary: Weight gain could be caused by Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Folic acid, and have Rheumatoid arthritis.

We study 129,658 people who have side effects while taking Methotrexate from FDA and social media. Among them, 1,301 have Weight gain. Find out below who they are, when they have Weight gain and more.

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Methotrexate

Methotrexate (latest outcomes from 130,985 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Weight gain

Weight gain (latest reports from 521,535 patients) has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol.

On Apr, 16, 2014: 129,658 people reported to have side effects when taking Methotrexate. Among them, 1,301 people (1.00%) have Weight Gain. They amount to 0.25% of all the 521,132 people who have Weight Gain on eHealthMe.

Trend of Weight gain in Methotrexate reports

Time on Methotrexate when people have Weight gain * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Weight gain47.71%20.18%4.59%11.93%10.09%3.67%1.83%

Gender of people who have Weight gain when taking Methotrexate * :

FemaleMale
Weight gain80.57%19.43%

Age of people who have Weight gain when taking Methotrexate * :

0-12-910-1920-2930-3940-4950-5960+
Weight gain0.27%3.30%4.81%4.90%11.41%19.61%27.54%28.16%

Severity of Weight gain when taking Methotrexate ** :

leastmoderateseveremost severe
Weight gain9.09%54.55%27.27%9.09%

How people recovered from Weight gain ** :

while on the drugafter off the drugnot yet
Weight gain0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (662 people, 50.88%)
  2. Pain (140 people, 10.76%)
  3. Hypertension (86 people, 6.61%)
  4. Vitamin supplementation (63 people, 4.84%)
  5. Arthritis (57 people, 4.38%)

Top co-used drugs for these people * :

  1. Folic acid (438 people, 33.67%)
  2. Enbrel (437 people, 33.59%)
  3. Prednisone (361 people, 27.75%)
  4. Humira (335 people, 25.75%)
  5. Omeprazole (120 people, 9.22%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Methotrexate, Weight gain

You can also:

On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Methotrexate used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

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More reviews for: Methotrexate, Weight gain

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- Methotrexate side effects

 

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- Weight Gain

 

 

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