Review: could Methotrexate cause Weight gain (Weight increased)?
Summary: Weight gain is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Folic acid, and have Rheumatoid arthritis.
We study 129,908 people who have side effects while taking Methotrexate from FDA and social media. Among them, 1,305 have Weight gain. Find out below who they are, when they have Weight gain and more.
You are not alone: join a support group for people who take Methotrexate and have Weight gain >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,259 Methotrexate users)
Weight gain has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol. (latest reports from 76,623 Weight gain patients)
On Mar, 26, 2015: 129,908 people reported to have side effects when taking Methotrexate. Among them, 1,305 people (1.00%) have Weight Gain.
Time on Methotrexate when people have Weight gain * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Weight gain||46.90%||20.35%||4.42%||12.39%||9.73%||3.54%||2.65% |
Gender of people who have Weight gain when taking Methotrexate * :
|Weight gain||80.62%||19.38% |
Age of people who have Weight gain when taking Methotrexate * :
|Weight gain||0.27%||3.29%||4.80%||4.88%||11.46%||19.63%||27.62%||28.06% |
Severity of Weight gain when taking Methotrexate ** :
|least||moderate||severe||most severe |
|Weight gain||6.67%||53.33%||26.67%||13.33% |
How people recovered from Weight gain ** :
|while on the drug||after off the drug||not yet |
|Weight gain||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Rheumatoid arthritis (664 people, 50.88%)
- Pain (140 people, 10.73%)
- Hypertension (86 people, 6.59%)
- Vitamin supplementation (63 people, 4.83%)
- Psoriatic arthropathy (58 people, 4.44%)
Top co-used drugs for these people * :
- Folic acid (441 people, 33.79%)
- Enbrel (437 people, 33.49%)
- Prednisone (362 people, 27.74%)
- Humira (336 people, 25.75%)
- Omeprazole (120 people, 9.20%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Get connected: join our support group of methotrexate and weight gain on
Do you have Weight Gain while taking Methotrexate?
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- support group for people who take Methotrexate and have Weight Gain
- support group for people who take Methotrexate
- support group for people who have Weight Gain
Drugs in real world that are associated with:
Could your condition cause:
- A study of drug interactions between Prednisone, Lisinopril, Prednisone, Myfortic, Prograf for a 59-year old woman with Transplant - Kidney, High Blood Pressure. The patient has Weight Gain, Blood Creatinine Increased
- A study of drug interactions between Folic Acid, Methotrexate, Enbrel for a 51-year old woman with Rheumatoid Arthritis. The patient has Nausea, Abdominal Pain
- A study of side effects of Lyrica for a 30-year old woman with Nerve Injury. The patient has Lower Sex Driver, Weight Gain, Hot Flush (sudden feelings of heat)
- A study of drug interactions between Metoprolol Succinate, Methotrexate Sodium Preservative Free, Plavix, Plaquenil, Humira, Folic Acid, Atorvastatin Calcium for a 59-year old woman with Coronary Artery Disease, Rheumatoid Arthritis, High Blood Cholesterol. The patient has Weight Gain
- A study of side effects of Lithium Carbonate for a 67-year old woman with Bipolar Disorder. The patient has Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development), Dry Mouth, Weight Gain, Sleepiness - During The Day (excess sleeping during day time)
Recent Methotrexate related drug comparison:
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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