Methotrexate and Withdrawal syndrome - from FDA reports


Summary

Withdrawal syndrome is found among people who take Methotrexate, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Lyrica, and have Pain . We study 209,150 people who have side effects while taking Methotrexate from FDA. Among them, 64 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

What to expect?

If you take Methotrexate and have Withdrawal syndrome, find out what symptoms you could have in 1 year or longer.

You are not alone!

Join a support group for people who take Methotrexate and have Withdrawal syndrome

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA since 1977. Our tools are simple to use, anonymous and free. Start now >>>

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,557 users)

Withdrawal Syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, back pain, muscle spasticity (latest reports from 13,481 Withdrawal syndrome patients).

On Jan, 29, 2017

209,150 people reported to have side effects when taking Methotrexate.
Among them, 64 people (0.03%) have Withdrawal Syndrome


Number of reports submitted per year:

Could Methotrexate cause Withdrawal syndrome?

Time on Methotrexate when people have Withdrawal Syndrome *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Withdrawal Syndrome when taking Methotrexate *:

  • female: 76.67 %
  • male: 23.33 %

Age of people who have Withdrawal Syndrome when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6 %
  • 20-29: 8 %
  • 30-39: 18 %
  • 40-49: 14 %
  • 50-59: 32 %
  • 60+: 22 %

Top conditions involved for these people *:

  • Pain (17 people, 26.56%)
  • Rheumatoid Arthritis (15 people, 23.44%)
  • Depression (14 people, 21.88%)
  • Fibromyalgia (11 people, 17.19%)
  • Back Pain (8 people, 12.50%)

Top co-used drugs for these people *:

  • Lyrica (24 people, 37.50%)
  • Folic Acid (17 people, 26.56%)
  • Humira (13 people, 20.31%)
  • Xanax (9 people, 14.06%)
  • Paxil (9 people, 14.06%)

Top other side effects for these people *:

  • Pain (19 people, 29.69%)
  • Feeling Abnormal (17 people, 26.56%)
  • Depression (13 people, 20.31%)
  • Nausea (12 people, 18.75%)
  • Agitation (12 people, 18.75%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Withdrawal syndrome when taking Methotrexate?

Browse all side effects of Methotrexate

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Withdrawal syndrome

Withdrawal syndrome

Could your condition cause Withdrawal syndrome

Withdrawal syndrome

Related studies

Can you answer these questions?

More questions for: Methotrexate, Withdrawal syndrome

You may be interested in these reviews

More reviews for: Methotrexate, Withdrawal syndrome