Methotrexate and Withdrawal syndrome - from FDA reports
Withdrawal syndrome is found among people who take Methotrexate, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Lyrica, and have Pain. This review analyzes which people have Withdrawal syndrome with Methotrexate. It is created by eHealthMe based on reports of 223,372 people who have side effects when taking Methotrexate from FDA, and is updated regularly.
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On May, 04, 2017
223,372 people reported to have side effects when taking Methotrexate.
Among them, 73 people (0.03%) have Withdrawal Syndrome
Number of reports submitted per year:
Time on Methotrexate when people have Withdrawal Syndrome *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Withdrawal Syndrome when taking Methotrexate *:
- female: 78.26 %
- male: 21.74 %
Age of people who have Withdrawal Syndrome when taking Methotrexate *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 6.78 %
- 20-29: 6.78 %
- 30-39: 15.25 %
- 40-49: 13.56 %
- 50-59: 35.59 %
- 60+: 22.03 %
Top conditions involved for these people *:
- Rheumatoid Arthritis (20 people, 27.40%)
- Pain (20 people, 27.40%)
- Depression (17 people, 23.29%)
- Fibromyalgia (16 people, 21.92%)
- Stress And Anxiety (10 people, 13.70%)
Top co-used drugs for these people *:
- Lyrica (30 people, 41.10%)
- Folic Acid (17 people, 23.29%)
- Humira (15 people, 20.55%)
- Xanax (11 people, 15.07%)
- Paxil (9 people, 12.33%)
Top other side effects for these people *:
- Pain (22 people, 30.14%)
- Feeling Abnormal (17 people, 23.29%)
- Nausea (13 people, 17.81%)
- Fatigue (13 people, 17.81%)
- Depression (13 people, 17.81%)
* Approximation only. Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Withdrawal syndrome when taking Methotrexate?
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 226,881 users)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, back pain, fibromyalgia (latest reports from 15,159 Withdrawal syndrome patients).
Browse all side effects of Methotrexatea b c d e f g h i j k l m n o p q r s t u v w x y z
Drugs that are associated with Withdrawal syndromeWithdrawal syndrome
Could your condition cause Withdrawal syndromeWithdrawal syndrome
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Can you answer these questions?
I started a low dose (10 mg) of methotrexate for rheumatoid arthritis last week and noticed this week, after taking my second does, that my face is breaking out. Does anyone have any similar experiences? I also take 5 mg of folic acid daily. Thanks for any help you can offer up.
Not sure what where to go with this. I have fibromyalgia and relapsing polchondritus also a disability from va.. I have my flares mostly under control. As well as what to do when they become apparent. After many years on pharmaceuticals I went a different direction. With medical marijauna. ...
Hi there, My names Adele I am 41 and have RA. I had my Gall Bladder removed in March of this year due to stones and constant infections. 2 years ago I stopped taking MTX subcutaneous and unfortunately my RA has progressed to a point I have (today) re-started these. I have headache, nausea and ...
Several years ago in 2013 I was"diagnosed" with RA. I went through every medication including, humira, embral, to now IV fusions of remicade which has been almost a year. I am not feeling any better and body aches and joint pains getting worse. I started researching my symptoms and lyme kept ...
This is for my father. Shortly after starting methotrexate injections and cortisone for Rheumatoid arthritis my father started having language difficulties and now has dementia. He was diagnosed with Pick's disease. Could it be caused by these drugs? He is still taking them.
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Hi there, I have advanced RH, no medications for over past 12 years. Had an extreme flare up a few months back so went to rheumatologist who has prescribed 10 mg methotrexate, weekly and daily palquil, 5mg prednisone and 2x weekly folic acid. I have been on them nearly 3 months now. This ...
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