Review: could Methotrexate cause Withdrawal syndrome?
Summary: Withdrawal syndrome is found among people who take Methotrexate, especially for people who are female, 30-39 old, have been taking the drug for < 1 month, also take medication Lyrica, and have Pain.
We study 129,908 people who have side effects while taking Methotrexate from FDA and social media. Among them, 44 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.
You are not alone: join a support group for people who take Methotrexate and have Withdrawal syndrome >>>
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,250 Methotrexate users)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, muscle spasticity, back pain. (latest reports from 9,228 Withdrawal syndrome patients)
On Mar, 18, 2015: 129,908 people reported to have side effects when taking Methotrexate. Among them, 44 people (0.03%) have Withdrawal Syndrome.
Time on Methotrexate when people have Withdrawal syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Withdrawal syndrome||100.00%||0.00%||0.00%||0.00%||0.00%||0.00%||0.00% |
Gender of people who have Withdrawal syndrome when taking Methotrexate * :
|Withdrawal syndrome||79.25%||20.75% |
Age of people who have Withdrawal syndrome when taking Methotrexate * :
|Withdrawal syndrome||0.00%||0.00%||2.27%||6.82%||50.00%||11.36%||25.00%||4.55% |
Severity of Withdrawal syndrome when taking Methotrexate ** :
How people recovered from Withdrawal syndrome ** :
Top conditions involved for these people * :
- Pain (23 people, 52.27%)
- Rheumatoid arthritis (14 people, 31.82%)
- Fibromyalgia (12 people, 27.27%)
- Back pain (11 people, 25.00%)
- Depression (10 people, 22.73%)
Top co-used drugs for these people * :
- Lyrica (19 people, 43.18%)
- Folic acid (12 people, 27.27%)
- Fentanyl-100 (11 people, 25.00%)
- Oxycodone hcl (9 people, 20.45%)
- Percocet (8 people, 18.18%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Get connected: join our support group of methotrexate and withdrawal syndrome on
Do you have Withdrawal Syndrome while taking Methotrexate?
You are not alone! Join a mobile support group on :
- support group for people who take Methotrexate and have Withdrawal Syndrome
- support group for people who take Methotrexate
- support group for people who have Withdrawal Syndrome
Drugs in real world that are associated with:
Could your condition cause:
- A study of drug interactions between Folic Acid, Methotrexate, Enbrel for a 51-year old woman with Rheumatoid Arthritis. The patient has Nausea, Abdominal Pain
- A study of drug interactions between Metoprolol Succinate, Methotrexate Sodium Preservative Free, Plavix, Plaquenil, Humira, Folic Acid, Atorvastatin Calcium for a 59-year old woman with Coronary Artery Disease, Rheumatoid Arthritis, High Blood Cholesterol. The patient has Weight Gain
- A study of drug interactions between Prednisolone, Plaquenil, Leflunomide, Methotrexate for a 63-year old woman with Rheumatoid Arthritis. The patient has Folliculitis
- A study of drug interactions between Folic Acid, Vitamin D, Zoloft, Methotrexate, Plaquenil for a 53-year old woman with Hair Loss, Iga Deficiency, Depression, Rheumatoid Arthritis, Lupus Erythematosus. The patient has Don't Want To Socialize At All
- A study of drug interactions between Fluoxetine, Omeprazole, Prednisone, Folic Acid, Enbrel, Methotrexate for a 56-year old woman with Depression, Chest Tightness Or Pressure, Rheumatoid Arthritis. The patient has Tremor
Recent Methotrexate related drug comparison:
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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