Review: could Methotrexate cause Withdrawal syndrome?
This is a review of Withdrawal syndrome by studying 124,856 people who take Methotrexate. We analyze: the time on Methotrexate when people have Withdrawal syndrome, gender and age of these people, the severity of Withdrawal syndrome, how they recovered, and common conditions and drugs used besides Methotrexate. The review is created by eHealthMe based on reports from FDA and social media, and is updated regularly.
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Methotrexate (latest outcomes from 130,928 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis, psoriatic arthritis. Commonly reported side effects of Methotrexate include fever, injection site pain, joint pain, nausea, nausea aggravated.
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) (latest reports from 52,538 patients) has been reported by people with depression, pain, acupuncture and pain, stress and anxiety, muscle spasticity.
On Feb, 23, 2014: 124,856 people reported to have side effects when taking Methotrexate. Among them, 40 people (0.03%) have Withdrawal Syndrome.
Time on Methotrexate when people have Withdrawal syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Withdrawal syndrome||100.00%||0.00%||0.00%||0.00%||0.00%||0.00%||0.00% |
Gender of people who have Withdrawal syndrome when taking Methotrexate * :
|Withdrawal syndrome||70.27%||29.73% |
Age of people who have Withdrawal syndrome when taking Methotrexate * :
|Withdrawal syndrome||0.00%||0.00%||3.57%||10.71%||21.43%||17.86%||39.29%||7.14% |
Severity of Withdrawal syndrome when taking Methotrexate ** :
How people recovered from Withdrawal syndrome ** :
Top conditions involved for these people * :
- Pain (15 people, 37.50%)
- Depression (10 people, 25.00%)
- Nerve injury (7 people, 17.50%)
- Psoriatic arthropathy (6 people, 15.00%)
- Rheumatoid arthritis (6 people, 15.00%)
Top co-used drugs for these people * :
- Lyrica (19 people, 47.50%)
- Folic acid (12 people, 30.00%)
- Xanax (8 people, 20.00%)
- Paxil (8 people, 20.00%)
- Humira (7 people, 17.50%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
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Related topic: Methotrexate, Withdrawal syndrome
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On eHealthMe, Methotrexate (methotrexate sodium) is often used for rheumatoid arthritis. Find out below the conditions Methotrexate is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
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