Methotrexate and Withdrawal syndrome - from FDA reports


Summary

Withdrawal syndrome is found among people who take Methotrexate, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Lyrica, and have Pain. This review analyzes which people have Withdrawal syndrome with Methotrexate. It is created by eHealthMe based on reports of 231,270 people who have side effects when taking Methotrexate from FDA , and is updated regularly.

What to expect?

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On Sep, 23, 2017

231,270 people reported to have side effects when taking Methotrexate.
Among them, 78 people (0.03%) have Withdrawal syndrome


Number of reports submitted per year:

Could Methotrexate cause Withdrawal syndrome?

Time on Methotrexate when people have Withdrawal syndrome *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Withdrawal syndrome when taking Methotrexate *:

  • female: 78.08 %
  • male: 21.92 %

Age of people who have Withdrawal syndrome when taking Methotrexate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.45 %
  • 20-29: 8.06 %
  • 30-39: 14.52 %
  • 40-49: 14.52 %
  • 50-59: 35.48 %
  • 60+: 20.97 %

Top conditions involved for these people *:

  • Pain (20 people, 25.64%)
  • Depression (17 people, 21.79%)
  • Fibromyalgia (16 people, 20.51%)
  • Stress And Anxiety (10 people, 12.82%)
  • Arthritis (8 people, 10.26%)

Top co-used drugs for these people *:

  • Lyrica (30 people, 38.46%)
  • Folic Acid (17 people, 21.79%)
  • Humira (16 people, 20.51%)
  • Xanax (11 people, 14.10%)
  • Paxil (9 people, 11.54%)

Top other side effects for these people *:

  • Pain (22 people, 28.21%)
  • Feeling Abnormal (17 people, 21.79%)
  • Nausea (13 people, 16.67%)
  • Fatigue (13 people, 16.67%)
  • Depression (13 people, 16.67%)

* Approximation only. Some reports may have incomplete information.

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Do you have Withdrawal syndrome when taking Methotrexate?

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Withdrawal syndrome and drugs with ingredients of methotrexate sodium.

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Withdrawal syndrome and Methotrexate from FDA and eHealthMe reports

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 234,878 users)

Withdrawal syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, fibromyalgia, back pain (latest reports from 16,148 Withdrawal syndrome patients).

Browse all side effects of Methotrexate

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Drugs that are associated with Withdrawal syndrome

Withdrawal syndrome

Could your condition cause Withdrawal syndrome

Withdrawal syndrome

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What would happen?

Forecast new side effects and undetected conditions when you take Methotrexate and have Withdrawal syndrome.

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