Review: could Metoprolol tartrate cause Sinus node dysfunction (Sick sinus syndrome)?
Summary: Sinus node dysfunction is found among people who take Metoprolol tartrate, especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years, also take medication Digoxin, and have Atrial fibrillation/flutter.
We study 38,548 people who have side effects while taking Metoprolol tartrate from FDA and social media. Among them, 75 have Sinus node dysfunction. Find out below who they are, when they have Sinus node dysfunction and more.
You are not alone: join a mobile support group for people who take Metoprolol tartrate and have Sinus node dysfunction >>>
Metoprolol tartrate has active ingredients of metoprolol tartrate. It is often used in high blood pressure. (latest outcomes from 40,460 Metoprolol tartrate users)
Sinus node dysfunction
Sinus node dysfunction (a group of abnormal heart rhythms) has been reported by people with high blood pressure, osteoporosis, diabetes, multiple myeloma, type 2 diabetes. (latest reports from 2,239 Sinus node dysfunction patients)
On Feb, 3, 2015: 38,528 people reported to have side effects when taking Metoprolol tartrate. Among them, 75 people (0.19%) have Sinus Node Dysfunction.
Time on Metoprolol tartrate when people have Sinus node dysfunction * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Sinus node dysfunction||20.00%||10.00%||10.00%||0.00%||0.00%||60.00%||0.00% |
Gender of people who have Sinus node dysfunction when taking Metoprolol tartrate * :
|Sinus node dysfunction||27.27%||72.73% |
Age of people who have Sinus node dysfunction when taking Metoprolol tartrate * :
|Sinus node dysfunction||0.00%||0.00%||0.00%||0.00%||0.00%||1.43%||4.29%||94.29% |
Severity of Sinus node dysfunction when taking Metoprolol tartrate ** :
How people recovered from Sinus node dysfunction ** :
Top conditions involved for these people * :
- Atrial fibrillation (17 people, 22.67%)
- Hypertension (8 people, 10.67%)
- Multiple myeloma (4 people, 5.33%)
- Prophylaxis (4 people, 5.33%)
- Type 2 diabetes mellitus (4 people, 5.33%)
Top co-used drugs for these people * :
- Digoxin (31 people, 41.33%)
- Aspirin (30 people, 40.00%)
- Warfarin sodium (20 people, 26.67%)
- Lasix (15 people, 20.00%)
- Norvasc (15 people, 20.00%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Sinus Node Dysfunction while taking Metoprolol Tartrate?
You are not alone! Join a mobile support group:
- support group for people who take Metoprolol tartrate and have Sinus Node Dysfunction
- support group for people who take Metoprolol tartrate
- support group for people who have Sinus Node Dysfunction
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I guess I fit the profile of who gets excessive sweating from HCTZ. I am a 65 year old female and suffered from excessive sweating for two years. With just very little exertion, I would pour sweat from the top of my head. It would run into my face and all over my hair. My hair would be ringing wet. I had heavy perspiration in the groin area and down my back also. I had to change clothing 2-3 times a day and wash up or shower that many times also. The doctor tried changing my Cymbalta and put me on Wellbutrin instead. It did absolutely no good. I went off the wellbutrin and back onto the Cymbalta. I did some research and saw that HCTZ could cause excessive sweating. Both my doctor and my pharmacist said that they had never heard of that. I went off the HCTZ, and my sweating stopped almost immediately. My doctor and my pharmacist were very surprised. I'm one of those people who frequently have different reactions to drugs than are typical. If you're having excessive perspiration and are on HCTZ, try going off of it. It just may be the culprit!
- Hydrochlorothiazide made me pour sweat
Hydroclorothiazide made me absolutely pour sweat for two years. My doctors could not find out what was causing the problem. It took little exertion for me to start dripping sweat. My hair would be absolutely soaked...especially in the summer, but if I was cleaning house in the winter also. I finally did my own research and proposed to my doctor that HCTZ was the problem. He did not agree with me, but agreed to let me go off of it for a short time. The profuse sweating stopped almost immediately.
- Pacemaker experience
I had a pacemaker installed about 5 weeks ago. I went to the doctors because I was feeling fatigue, shortness of breath, I felt as if someone was holding my heart in their hand and I had some confusion and dizziness.
To get to the point, after my first visit with my PCP I decided to go directly to emergency via 911 since my PCP was basically ignoring, or better put, had no sense of urgency regarding how I was feeling even though she knew my heart rate had dropped and was steady at 44 bpm, my normal rate 62 bpm.
The night I was in observation at the hospital I dropped to 20 bpm, next day I had a pacemaker installed, had I not taken the initiative to call the hospital I don't know if I would have continued dropping until I was dead, I don't know enough about the science behind this to draw that conclusion but common sense tells me yes.
I have explained this in another post but I cannot find it, not sure what I am doing wrong, so I am writing another post because I have more to add after a couple of weeks since my last post.
The issue I have is I am still tired after more than a month after the installation of the pacemaker. I had the bpm (beats per minute) on my pacemaker increased from 60, the factory settings, to somewhere in the mid 60's.......so I thought. I went to the hospital twice to have my pacemaker "tweaked" but when I met with the cardiologist for my "one week" follow up, which took almost three weeks to see him due to his heavy schedule, he told me there were never any changes made to my pacemaker, I was still at 60 bpm. How could this be since I was told twice it had been increased? I had the wand on my chest and the nurse made the changes which were made due to my complaining about being exhausted still, the reason I went to the PCP in the first place five weeks ago.
Was she playing mind games, thinking the power of suggestion would make me feel better? If so I am disgusted to think she would feel I was faking my feelings of exhaustion, what she did had absolutely no effect on how poorly I was feeling.
To get to the point, I finally had my first meeting with the surgeon, he raised my bpm to 75 from 60, was going to go to 80 but changed his mind. The moment he made the change to 75 bpm from my original 60 he asked if I was feeling better, feeling better after 60 seconds of changing the bpm, how is that possible? I told him no, kind of too soon to tell. His reply was "it looks like we have done everything we can on our end, your heart was not significantly damaged, your pacemaker is working as it should, therefore there must be something else making you feel so poorly so I suggest you see an internal medicine specialist." My brain had a big WHAT sign flashing, I couldn't believe what he was saying, basically beat it and move on, I don't have the time to deal with you anymore. Lets see, the appointment lasted 25 minutes and he does not have the time to work with me anymore, sorry but that irritates the hell out of me.
He was washing his hands of me, nothing else he could do so spend time and money finding out what the problem is with an internest, it is not my heart according to the cardiologist. The appointment ended and I left wondering how I was going to find out what is causing my issues.
To my great fortune a nurse with 20 years experience teaching doctors and nurses how to use the pacemaker computer asked me to come into her office after my appointment with the cardiologist, she asked me this prior to seeing the doctor. Thank God she did as the doctor did not do a thorough job adjusting the pacemaker, she adjusted what the doctor had, tweaked the pacemaker a bit, had me walk for 10 minutes and come back to the office and did a bit more tweaking, I slowly started feeling a touch better. She asked me to come back in two weeks and she would see if the pacemaker needed to be tweaked a bit more. I was walking on air, still not close to my "normal", thrilled I was not just a number being tossed in the heap of unfixed people. I am feeling 70% better than how I felt prior to the doctor and her tweaking the pacemaker. Had she not been there that day and had the opportunity to do this I would be on a never ending search for what is making me feel so exhausted and!
There is a moral to this which I will let you draw your own conclusion. In my mind it is trust God will intervene, he certainly did when the nurse asked me to see her after the appointment with the surgeon. The reason I feel this way is because she was there and is only there on Fridays, the day I had my appointment. I never would have gone back again after my meeting with the doctor and I would have been spending needless hours and money looking through the wrong box for what ales me. Now it is obvious it was my pacemaker settings, my heart rate was set too low and the pacemaker was not fine tuned properly with the proper slope and other settings.
Don't let these doctors do what mine tried doing with me, be aggressive and insist on more adjustments if you have issues similar to mine.
AS I sit here I am still tired, I could easily take a nap but I am better than I was yesterday, significantly.
Best of luck to all. Your comments will be very much appreciated.
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Comments from related studies:
From this study (2 days ago):
had 2 stents put in sept. 2013 and since have heart pounding sensation especially after eating supper , can walk , skate , ride a bike for a few miles without any pain .......i have a feeling it may be lipitor as my legs ache at night shoulder joints hurt , no energy....lipitor seems to have a lot of side effects, could it be causing this pounding sensation also ?
From this study (1 week ago):
I have had 2 ocular migraines with elevated blood pressure this month. Could it be the Zantac? I took one last night for heartburn and had an ocular migraine this morning. Lately I have had a lot of flushing of the face and wake up with my face flushed in the morning although my blood pressure has been normal. I have had heartburn since taking the Lopressor and Norvasc and that is why I started on the Zantac OTC. I used to have ocular migraines about 30 years ago and they were related to decongestants.
Carmie on Jan, 26, 2015:
I am wondering if any of the above drugs could be causing my flashing lights type migraine. I do not have any severe pain with this. Could it be drug interaction and which one is causing the flushing of the face and heartburn. It did not start until I started the Lopressor and Norvasc.
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