Review: could Metronidazole cause Toxic Encephalopathy?


Summary

Toxic encephalopathy is found among people who take Metronidazole, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Ceftriaxone, and have Brain abscess . We study 12,808 people who have side effects while taking Metronidazole from FDA and social media. Among them, 93 have Toxic encephalopathy. Find out below who they are, when they have Toxic encephalopathy and more.

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Metronidazole

Metronidazole has active ingredients of metronidazole. It is often used in infection. (latest outcomes from Metronidazole 13,582 users)

Toxic Encephalopathy

Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances) (latest reports from 894 Toxic encephalopathy patients).

On Jul, 27, 2016

12,808 people reported to have side effects when taking Metronidazole.
Among them, 93 people (0.73%) have Toxic Encephalopathy


Number of reports submitted per year:

Could Metronidazole cause Toxic encephalopathy?

Time on Metronidazole when people have Toxic Encephalopathy *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Toxic Encephalopathy when taking Metronidazole *:

  • female: 30.99 %
  • male: 69.01 %

Age of people who have Toxic Encephalopathy when taking Metronidazole *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.88 %
  • 30-39: 13.24 %
  • 40-49: 17.65 %
  • 50-59: 25.0 %
  • 60+: 38.24 %

Top conditions involved for these people *:

  • Brain Abscess (8 people)
  • Osteomyelitis (6 people)
  • Infection (5 people)
  • Enterocolitis Infectious (5 people)
  • Pneumonia (4 people)

Top co-used drugs for these people *:

  • Ceftriaxone (10 people)
  • Vancomycin (5 people)
  • Omeprazole (4 people)
  • Cefotaxime (4 people)
  • Baclofen (4 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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