Metronidazole and Toxic encephalopathy - from FDA reports


Summary

Toxic encephalopathy is found among people who take Metronidazole, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Ceftriaxone, and have Brain abscess . We study 20,441 people who have side effects while taking Metronidazole from FDA. Among them, 175 have Toxic encephalopathy. Find out below who they are, when they have Toxic encephalopathy and more.

What to expect?

If you take Metronidazole and have Toxic encephalopathy, find out what symptoms you could have in 1 year or longer.

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Metronidazole

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. (latest outcomes from Metronidazole 21,684 users)

Toxic Encephalopathy

Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances) has been reported by people with herpes zoster, pain, high blood pressure, epilepsy, depression (latest reports from 1,712 Toxic encephalopathy patients).

On Feb, 20, 2017

20,441 people reported to have side effects when taking Metronidazole.
Among them, 175 people (0.86%) have Toxic Encephalopathy


Number of reports submitted per year:

Could Metronidazole cause Toxic encephalopathy?

Time on Metronidazole when people have Toxic Encephalopathy *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Toxic Encephalopathy when taking Metronidazole *:

  • female: 41.84 %
  • male: 58.16 %

Age of people who have Toxic Encephalopathy when taking Metronidazole *:

  • 0-1: 0.72 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.97 %
  • 30-39: 6.52 %
  • 40-49: 14.49 %
  • 50-59: 23.91 %
  • 60+: 46.38 %

Top conditions involved for these people *:

  • Brain Abscess (27 people, 15.43%)
  • Diarrhea (13 people, 7.43%)
  • Osteomyelitis (12 people, 6.86%)
  • Clostridium Difficile Colitis (7 people, 4.00%)
  • Pyogenic Liver Abscess (6 people, 3.43%)

Top co-used drugs for these people *:

  • Ceftriaxone (13 people, 7.43%)
  • Pantoprazole (5 people, 2.86%)
  • Omeprazole (4 people, 2.29%)
  • Lactulose (4 people, 2.29%)
  • Baclofen (4 people, 2.29%)

Top other side effects for these people *:

  • Speech Impairment (adult) (35 people, 20.00%)
  • Movement - Uncoordinated (21 people, 12.00%)
  • Cerebellar Syndrome (19 people, 10.86%)
  • Nuclear Magnetic Resonance Imaging Brain Abnormal (15 people, 8.57%)
  • Paraesthesia (14 people, 8.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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