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Review: could Mirapex cause Anxiety?

Summary: Anxiety could be caused by Mirapex, especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years, also take Sinemet, and have Restless legs syndrome.

We study 9,705 people who have side effects while taking Mirapex from FDA and social media. Among them, 809 have Anxiety. Find out below who they are, when they have Anxiety and more.

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Mirapex (latest outcomes from 10,283 users) has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome.


Anxiety (latest reports from 1,272,509 patients) has been reported by people with depression, stress and anxiety, quit smoking, multiple sclerosis, pain.

On Apr, 10, 2014: 9,705 people reported to have side effects when taking Mirapex. Among them, 821 people (8.46%) have Anxiety. They amount to 0.06% of all the 1,270,853 people who have Anxiety on eHealthMe.

Trend of Anxiety in Mirapex reports

Time on Mirapex when people have Anxiety * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Anxiety when taking Mirapex * :


Age of people who have Anxiety when taking Mirapex * :


Severity of Anxiety when taking Mirapex ** :

leastmoderateseveremost severe

How people recovered from Anxiety ** :

while on the drugafter off the drugnot yet

Top conditions involved for these people * :

  1. Restless legs syndrome (489 people, 59.56%)
  2. Parkinson's disease (421 people, 51.28%)
  3. Depression (169 people, 20.58%)
  4. Anxiety (112 people, 13.64%)
  5. Insomnia (82 people, 9.99%)

Top co-used drugs for these people * :

  1. Sinemet (278 people, 33.86%)
  2. Klonopin (152 people, 18.51%)
  3. Ambien (149 people, 18.15%)
  4. Xanax (138 people, 16.81%)
  5. Nexium (137 people, 16.69%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Mirapex, Anxiety

You can also:

On eHealthMe, Mirapex (pramipexole dihydrochloride) is often used for restless leg syndrome. Find out below the conditions Mirapex is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Mirapex used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (3 months ago):

  • History of depression/anxiety - occasional panic attacks, long term mental illness/alcohol abuse. Atrial fibrillation diagnosed October 2013


  • From this study (6 months ago):

  • rls became quite worse dr took off pramipexole and just 2 weeks on ropinirole working up to 3mg, not helping yet


  • From this study (4 years ago):

  • Hi I have been on 75 mg of Effexor Xr for over 10 years but due to a certain life crisis I went up to 150mg about a month before i started mirapex. I slowly went up on my dose of mirapex starting at .25 mg and increasing by a mg every 7 days. I am now on 1.5mg and still experiencing pmld/rls before if fall asleep but it is lessened in intensity. I am not able to see the specialist for another month and am concerned about the side effects...and wondering are they coming from the mirapex or the amount of effexor that I'm taking. In researching mirapex I have found that it increases sex drive...and mine is at zero, and it has always been very good. Any advise would be soooo appreciated. Should I go back to 75 mg of effexor and see if I am able to cope with little depression or should I cut down on the it the higher you go on mirapex, the more of the side effects??? Thank you for any information!!!


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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Related study

- Mirapex side effects


Related symptom

- Anxiety



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