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Review: could Mirena cause Mood swings?

Summary: Mood swings could be caused by Mirena, especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months, also take Wellbutrin, and have Contraception.

We study 62,483 people who have side effects while taking Mirena from FDA and social media. Among them, 993 have Mood swings. Find out below who they are, when they have Mood swings and more.

On Apr, 10, 2014: 62,587 people reported to have side effects when taking Mirena. Among them, 993 people (1.59%) have Mood Swings. They amount to 0.83% of all the 119,385 people who have Mood Swings on eHealthMe.

Trend of Mood swings in Mirena reports

Time on Mirena when people have Mood swings * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Mood swings10.36%28.60%19.37%17.34%18.47%5.86%0.00%

Age of people who have Mood swings when taking Mirena * :

0-12-910-1920-2930-3940-4950-5960+
Mood swings0.00%0.00%2.43%38.65%42.03%16.35%0.54%0.00%

Severity of Mood swings when taking Mirena ** :

leastmoderateseveremost severe
Mood swings0.00%31.25%56.25%12.50%

How people recovered from Mood swings ** :

while on the drugafter off the drugnot yet
Mood swings0.00%11.11%88.89%

Top conditions involved for these people * :

  1. Contraception (673 people, 67.77%)
  2. Menorrhagia (81 people, 8.16%)
  3. Premenstrual syndrome (16 people, 1.61%)
  4. Vaginal haemorrhage (10 people, 1.01%)
  5. Anxiety (9 people, 0.91%)

Top co-used drugs for these people * :

  1. Wellbutrin (12 people, 1.21%)
  2. Cymbalta (10 people, 1.01%)
  3. Zoloft (10 people, 1.01%)
  4. Yasmin (7 people, 0.70%)
  5. Clonazepam (6 people, 0.60%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Mirena, Mood swings

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On eHealthMe, Mirena (levonorgestrel) is often used for birth control. Find out below the conditions Mirena is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Mirena used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (11 months ago):

  • I have been diagnosed with anxiety, emotioally unstable personality, anxiety, depression, migraines, non-epiltpic attacks, sleep seizures, night terrors, and PTSD
    Have recently had coil fitted very tired

    Reply

  • From this study (11 months ago):

  • I DO NOT recommend this device for ANYONE. I have had it for 13 months and it has completely changed every aspect of my life. All of my symptoms began around the 12-month mark except the excess vaginal secretions and odor which began almost instantly. I also blacked out for the first time in my ife while using Mirena which was the most terrifying experience I have ever had.

    It does prevent pregnancy but it is ruining my physical and mental health. I hope to have it removed soon.
    Hopefully this will help anyone out there in my situation. You don't have to take my word for it either. Research it on your own.

    Reply

    Lisa on Mar, 9, 2013:

    I am 34 yr old female who chose to have the IUD placed for painful/heavy periods after having side effects from oral birth control. I had it placed 3 months ago. Since then I have had severe mood swings ranging from anger/aggitation to severe depression. I have gain 15 pounds (in 3 months), all in my abdomen- I look 6-7 months pregnant and no longer fit in any of my pants. I have severe headaches from the moment I wake up until I go to bed- to the point it feels like my head will explode- I take 3 aleve daily and that does nothing for the pain. I have no sex drive, and started having vaginal dryness- for which I was prescibed a vaginal estrogen cream.When the IUD was placed, I bled for almost the whole 3 months to the point I am anemic. I have changed NOTHING in my lifestyle since having the Mirena placed- I am active, work out 3-4 days a week, eat healthy. So, since having the Mirena placed I am on Iron for anemia, been on 2 different anti-depressants, have a vaginal cream. I have called my Dr who said all these side effects are 'normal'. It is not NORMAL for me- I am NOT the same person I was only 3 months ago. I am having this taken out as soon as possible. I am a nurse, and thought I researched this enough, until I started reading these blogs and see how many women have had the same side effects. Some women have had none. I STRONGLY encourage any woman to read more than what the medical and IUD websites state- read what real women are feeling.

    Reply

    Mandy on Mar, 10, 2013:

    I have been having some of the same effects I informed my OB/GYN that I would probly want top have it removed. They told me that the insurance said when they paid for it I would have to try it for six months.I didn't remember them telling me that nore did I sign an agreement. When I got upset about this they sent me a letter that they dropped me as a patient. Now how am I supposed to get this thing out?

    Reply

    Maria on Jun, 2, 2013:

    I had my mirena put in 11 months ago for horrible cramps and heavy periods. I started having breast tenderness, severe mood swings, then milky nipple drainage. I was also having pregnancy symptoms. I reported ithese symptoms to my object/gyn and dismissed them. I was pissed. I took matters into my own hand. I consulted a homeopathic doctor. I take some supplements from natures sunshine called liver balance and proactizyme. I feel sooooooo much better. If i deviate from the amount im supposed to take all the symptoms come back. Good luck to you. Know there is hope for feeling better.

    Reply

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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