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Review: could Mirtazapine cause Peripheral edema (Oedema Peripheral)?

Summary: Peripheral edema is found among people who take Mirtazapine, especially for people who are female, 50-59 old, have been taking the drug for < 1 month, also take medication Furosemide, and have Depression.

We study 17,101 people who have side effects while taking Mirtazapine from FDA and social media. Among them, 379 have Peripheral edema. Find out below who they are, when they have Peripheral edema and more.

You are not alone: join a support group for people who take Mirtazapine and have Peripheral edema >>>



Mirtazapine has active ingredients of mirtazapine. It is often used in depression. (latest outcomes from 17,969 Mirtazapine users)

Peripheral edema

On Apr, 20, 2015: 17,101 people reported to have side effects when taking Mirtazapine. Among them, 379 people (2.22%) have Peripheral Edema.

Trend of Peripheral edema in Mirtazapine reports

Time on Mirtazapine when people have Peripheral edema * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Peripheral edema60.55%31.19%2.75%4.59%0.00%0.00%0.92%

Gender of people who have Peripheral edema when taking Mirtazapine * :

Peripheral edema73.22%26.78%

Age of people who have Peripheral edema when taking Mirtazapine * :

Peripheral edema0.00%0.00%0.82%2.47%7.95%18.90%35.89%33.97%

Severity of Peripheral edema when taking Mirtazapine ** :


How people recovered from Peripheral edema ** :


Top conditions involved for these people * :

  1. Depression (127 people, 33.51%)
  2. Anxiety (29 people, 7.65%)
  3. Schizoaffective disorder (28 people, 7.39%)
  4. Pain (23 people, 6.07%)
  5. Insomnia (23 people, 6.07%)

Top co-used drugs for these people * :

  1. Furosemide (68 people, 17.94%)
  2. Lyrica (54 people, 14.25%)
  3. Levothyroxine sodium (53 people, 13.98%)
  4. Aspirin (52 people, 13.72%)
  5. Simvastatin (51 people, 13.46%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

john (2 years ago):

I am a male 50 yrs old and diagnosed with PTSD. The following evening having taken the 1st of my mirtazapine 30mg i began to experience a rather heavy bleed in my left eye. Is this normal? Dangerous? Any suggestions please.
Reply the comment

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Peripheral Edema while taking Mirtazapine?




You are not alone! Join a support group on :
- support group for people who take Mirtazapine and have Peripheral Edema
- support group for people who take Mirtazapine

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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