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Review: could Mirtazapine cause Tiredness (Fatigue)?

Summary: Tiredness is found among people who take Mirtazapine, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Lorazepam, and have Depression.

We study 17,088 people who have side effects while taking Mirtazapine from FDA and social media. Among them, 897 have Tiredness. Find out below who they are, when they have Tiredness and more.

You are not alone: join a mobile support group for people who take Mirtazapine and have Tiredness >>>

 

 

 

 

Mirtazapine

Mirtazapine has active ingredients of mirtazapine. It is often used in depression. (latest outcomes from 17,940 Mirtazapine users)

Tiredness

Tiredness (feeling of tiredness) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis. (latest reports from 200,495 Tiredness patients)

On Dec, 31, 2014: 17,080 people reported to have side effects when taking Mirtazapine. Among them, 897 people (5.25%) have Tiredness.

Trend of Tiredness in Mirtazapine reports

Time on Mirtazapine when people have Tiredness * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Tiredness46.38%36.23%6.52%4.35%3.62%2.17%0.72%

Gender of people who have Tiredness when taking Mirtazapine * :

FemaleMale
Tiredness62.23%37.77%

Age of people who have Tiredness when taking Mirtazapine * :

0-12-910-1920-2930-3940-4950-5960+
Tiredness0.00%0.49%0.73%6.70%12.67%13.52%24.97%40.93%

Severity of Tiredness when taking Mirtazapine ** :

leastmoderateseveremost severe
Tiredness0.00%46.15%46.15%7.69%

How people recovered from Tiredness ** :

while on the drugafter off the drugnot yet
Tiredness0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Depression (266 people, 29.65%)
  2. Hypertension (107 people, 11.93%)
  3. Pain (78 people, 8.70%)
  4. Insomnia (77 people, 8.58%)
  5. Anxiety (76 people, 8.47%)

Top co-used drugs for these people * :

  1. Lorazepam (158 people, 17.61%)
  2. Aspirin (116 people, 12.93%)
  3. Simvastatin (106 people, 11.82%)
  4. Potassium chloride (99 people, 11.04%)
  5. Clonazepam (95 people, 10.59%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Tiredness while taking Mirtazapine?

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- support group for people who take Mirtazapine and have Tiredness
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- support group for people who have Tiredness

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  • Transition from mirtazapine to cymbalta (bipolar ii) 6 week duration taken in conjunction with seroquel, propranalol and implanon
    In early September I approached my Psychiatrist to report that I was having sleep paralysis episodes as well as insatiable appetite. I had put on about 20lb in the space of 6 months since the sleep paralysis started.

    My Psychiatrist opted to wean me off the Mirtazapine and onto Cymbalta. I have now been on 60mg of Cymbalta for about 4 weeks and completely titrated off the Mirtazapine.

    I have noted that since switching to Cymbalta that I no longer have the insatiable appetite, nor have I had any further sleep paralysis episodes (though I have had a brain MRI to rule out any physiological issues - yet to receive results).

    I have noticed that I have had mild to moderate rolling nausea with the Cymbalta and that I now have food aversions. Food does not interest me as much anymore and I find that certain foods (mostly processed snacks) are no longer palatable. I also find that I become full after much smaller meal portions.

    I have found that I can no longer drink wine or spirits because they now taste awful however I can still tolerate certain brands of beer. I also no longer enjoy drinking cola.

    I am also on the Implanon Implant. I have had this implant inserted for about 12 months and my cycles have been rather regular. Since starting the Cymbalta I have had some breakthrough bleeding yet my periods have not been as painful, though they have been heavier and longer.

    My Psychiatrist will commence titrating me off the Seroquel in about two weeks and onto Topamax as it is his belief it will be less sedating than the Seroquel and that it will hopefully help as a mood stabiliser, treat my migraines and allow me to come off the Propranolol. he also hopes that I am able to loose some of the weight gained since the sleep paralysis episodes started.

    As a side note regarding the Propranolol, I have naturally low blood pressure and I find while Propranalol is generally an effective migraine prophylactic, (I do get some breakthrough migraines) it does make my blood pressure even lower which leads to dizziness and faintness when I stand up too quickly from a recumbent position.
  • Diagnosed with postural orthostatic tachycardia syndrome after mirena
    After getting the Mirena put in, I got really sick. I went home and got super dizzy, nauseous, and tired. I felt so sick and could barely function. I called the doctors office and they said it couldn't be from the Mirena. She said that I must have the flu. Well, I kept it in for a little while longer. I then started losing my hair. I went back into my doctors office because they thought I was experiencing the symptoms for the Mirena going through my uterine wall. The ultra sound was fine. She reassured me that the Mirena could not be the cause of my complications. So, a week a later I went to another doctor to have the Mirena taken out.
    Never quite felt like myself and a year later I got diagnosedI with Postural Orthostatic Tachycardia Syndrome, after a tilt table test was performed. It's weird to me that my symptoms started almost immediately after the Mirena was put in.
  • Mucinex dm and advil congetstion
    I noticed another female with simlar age and side effects; and a third female who in addition was under active thyroid. I have taken both drugs independently and had no problem with them. I am prone to low blood pressure & dizziness due to the thyroid problem
  • Patients having false positives while on remeron
    I have had a few patients complain they are failing drug tests for Amphetamines while on remeron, and have claimed to have not used any type of Amphetamine or any (Mixed Salts). These patients are all or were on probation, parole, or under some stipulation. Iv realized most of these patients are taking another psych med. The list consists of insomnia meds such as Ambien(zolpidem), Sonata(zaleplon),Lunesta(eszopiclone). Also the Anti-Depressants Lexapro (escitalopram)and Prozac (fluoxetine). One of my patients was on Diazepam (Valium). I have switched medicines, particularly the Ambien, Lexapro, and Prozac have reversed the false negative. I prescribe many of my patients remeron. I'm a big believer in its effects on my patients moods and everyday depression. I have heard this happening before, but this was the first time I have ever had this happen to one of my own patients.(These were 5 separate patients in the span of 16 months) Of course none of these patients were criminalized based on lab results, but the issue still lies there. I know this is common for a lot of script meds to give false positives for narcotics. This is just obviously one I am putting out there. Let me know if anyone has experienced something similar.
  • How an integrative wellness approach cured me of insomnia, ibs, and more (1 response)
    For 10+ years, I suffered with insomnia and a host of other problems including intestinal distress, headaches, psoriasis, anxiety, cognitive issues, hypothyroid, chronic itching, restless leg, etc. Traditional medicine, aka taking drugs, was not working to heal me. Since childhood, I’ve had IBS, headaches, and upper respiratory problems. Then, in my early twenties, after childbirth, I begin to suffer with panic attacks. I managed to get the panic attacks under control, but the insomnia never went away. I took both Ambien and Clonazepam at different times in my life. When I expressed my concern over taking these meds, my doctor reassured me and told me that some people just have to take sleeping meds for their entire life. I read literature on insomnia and tried most everything – no late night eating, no TV or electronics before bed, sleep in a cool room with complete darkness, meditate, sleep labs, etc. etc. etc. Even with the sleeping meds, I never got restful sleep. Most days, I felt like it was all I could do just to get by. For at least the first half of each day, I felt that I was in dazed stupor until the meds in me would start to wear off. I was first on Clonazepam and then switched to Ambien. When I made the switch, I suffered through withdrawal for about a week. It was horrible -- no sleep, hallucinations, etc. For years, I had silently suffered – my family, friends, and colleagues having no idea to what extent. I felt that mentally, cognitively, and physically I was slowly slipping away. My love for my child and my desire to nurture and provide for him is what kept me going. Without this purpose in my life, I fear that I might have given up somewhere along the way.

    Finally, a few years ago, I went to see an integrative medicine doctor. After years of being in the darkness, I am finally living again. My IM doctor put me on natural supplements, a natural thyroid replacement, and, most importantly, tested me for food allergies/sensitivities. My test results yielded that I could not tolerate wheat, gluten, yeast, and dairy. I took these results seriously and I completely eliminated these things from my diet. After two weeks of adhering to my new diet, I already felt better. In fact, I felt so much better, that, one evening, I decided not to take my Ambien. I have not taken it or any sleep or anxiety medicine since. My doctor was as surprised as I was and did not really anticipate that the diet alone would cure my insomnia. In fact, he had told me that, since I had been taking sleeping meds for so long, eliminating them completely would be a long process that we would have to work through together. Nearly all of the symptoms I listed have disappeared. I continue to take my natural thyroid replacement and the supplements my doctor suggested. I have the occasional migraine and a few patches of psoriasis -- but nothing like the severity I had before. I am 47 now and I am on a journey of healthy transformation. I eat healthy foods, exercise regularly, and truly feel healthy, younger, and physically stronger than I have in 15 and maybe 20 years. Jokingly, my husband used to refer to me as "fragile." Well, not anymore. In fact, he has told me that my body seems like a completely different one. He has had a front-row seat to my transformation and he is as much "in awe" of the changes in me as I am in myself.

    Ten years ago, I was not optimist about my future. Today, I am full of hope, wonder, energy, and excitement. I believe we have the ability to heal ourselves, but we must be diligent in our pursuit of knowledge, persistent and strong in our will to make lifestyle changes, and patient that results will come as long as we are doing all the right things. By the way, giving up foods I had eaten my entire life was not difficult at all once I did it long enough to realize the tremendous benefits of not eating them.

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