Review: could Morphine Sulfate cause Depression?


Depression is found among people who take Morphine Sulfate, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Oxycontin, and have Pain . We study 18,509 people who have side effects while taking Morphine sulfate from FDA and social media. Among them, 548 have Depression. Find out below who they are, when they have Depression and more.

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Morphine Sulfate

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. (latest outcomes from Morphine sulfate 19,412 users)


Depression has been reported by people with suicidal ideation, pain, drug ineffective, insomnia, fatigue (latest reports from 272,927 Depression patients).

On Aug, 17, 2016

18,509 people reported to have side effects when taking Morphine Sulfate.
Among them, 548 people (2.96%) have Depression

Number of reports submitted per year:

Could Morphine sulfate cause Depression?

Time on Morphine Sulfate when people have Depression *:

  • < 1 month: 41.07 %
  • 1 - 6 months: 19.64 %
  • 6 - 12 months: 12.5 %
  • 1 - 2 years: 8.93 %
  • 2 - 5 years: 14.29 %
  • 5 - 10 years: 3.57 %
  • 10+ years: 0.0 %

Gender of people who have Depression when taking Morphine Sulfate *:

  • female: 54.38 %
  • male: 45.62 %

Age of people who have Depression when taking Morphine Sulfate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.86 %
  • 20-29: 5.14 %
  • 30-39: 13.06 %
  • 40-49: 27.41 %
  • 50-59: 25.27 %
  • 60+: 28.27 %

Severity if Depression when taking Morphine Sulfate **:

  • least: 7.69 %
  • moderate: 53.85 %
  • severe: 38.46 %
  • most severe: 0.0 %

How people recovered from Depression **:

  • while on drug: 0.0 %
  • after off the drug: 20 %
  • not yet: 80 %

Top conditions involved for these people *:

  • Pain (174 people)
  • Depression (68 people)
  • Multiple Myeloma (48 people)
  • Metastases To Bone (38 people)
  • Anxiety (33 people)

Top co-used drugs for these people *:

  • Oxycontin (194 people)
  • Zometa (183 people)
  • Neurontin (148 people)
  • Ambien (134 people)
  • Ms Contin (130 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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