Review: could Morphine cause Agitation?


Agitation is found among people who take Morphine, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Fentanyl, and have Pain . We study 33,999 people who have side effects while taking Morphine from FDA and social media. Among them, 652 have Agitation. Find out below who they are, when they have Agitation and more.

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Morphine has active ingredients of morphine sulfate. It is often used in pain. (latest outcomes from Morphine 55,422 users)


Agitation (state of anxiety or nervous excitement) has been reported by people with type 2 diabetes, death, drug ineffective, drowsiness, arrhythmias (latest reports from 61,465 Agitation patients).

On Aug, 24, 2016

33,999 people reported to have side effects when taking Morphine.
Among them, 652 people (1.92%) have Agitation

Number of reports submitted per year:

Could Morphine cause Agitation?

Time on Morphine when people have Agitation *:

  • < 1 month: 82.69 %
  • 1 - 6 months: 7.69 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 7.69 %
  • 5 - 10 years: 1.92 %
  • 10+ years: 0.0 %

Gender of people who have Agitation when taking Morphine *:

  • female: 41.95 %
  • male: 58.05 %

Age of people who have Agitation when taking Morphine *:

  • 0-1: 1.55 %
  • 2-9: 2.41 %
  • 10-19: 5.34 %
  • 20-29: 2.75 %
  • 30-39: 10.33 %
  • 40-49: 20.48 %
  • 50-59: 16.35 %
  • 60+: 40.79 %

Severity if Agitation when taking Morphine **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Pain (112 people)
  • Depression (47 people)
  • Back Pain (35 people)
  • Nausea (25 people)
  • Agitation (23 people)

Top co-used drugs for these people *:

  • Fentanyl (78 people)
  • Propofol (70 people)
  • Lorazepam (63 people)
  • Acetaminophen (59 people)
  • Aspirin (55 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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