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Review: could Morphine cause Memory impairment?

Summary: Memory impairment could be caused by Morphine, especially for people who are female, 50-59 old, have been taking the drug for < 1 month, also take Morphine sulfate, and have Pain.

We study 48,599 people who have side effects while taking Morphine from FDA and social media. Among them, 757 have Memory impairment. Find out below who they are, when they have Memory impairment and more.

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Morphine (latest outcomes from 49,685 users) has active ingredients of morphine sulfate. It is often used in pain.

Memory impairment

Memory impairment (latest reports from 461,337 patients) has been reported by people with multiple sclerosis, depression, high blood pressure, pain, pain relief by acupuncture.

On Apr, 11, 2014: 48,578 people reported to have side effects when taking Morphine. Among them, 757 people (1.56%) have Memory Impairment. They amount to 0.16% of all the 460,868 people who have Memory Impairment on eHealthMe.

Trend of Memory impairment in Morphine reports

Time on Morphine when people have Memory impairment * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Memory impairment46.88%10.94%12.50%6.25%15.62%7.81%0.00%

Gender of people who have Memory impairment when taking Morphine * :

Memory impairment64.85%35.15%

Age of people who have Memory impairment when taking Morphine * :

Memory impairment0.00%0.00%1.19%4.61%13.97%21.61%29.64%28.99%

Severity of Memory impairment when taking Morphine ** :

leastmoderateseveremost severe
Memory impairment8.33%83.33%8.33%0.00%

How people recovered from Memory impairment ** :

while on the drugafter off the drugnot yet
Memory impairment14.29%0.00%85.71%

Top conditions involved for these people * :

  1. Pain (241 people, 31.84%)
  2. Breast cancer (40 people, 5.28%)
  3. Metastases to bone (39 people, 5.15%)
  4. Depression (36 people, 4.76%)
  5. Hepatitis c (36 people, 4.76%)

Top co-used drugs for these people * :

  1. Morphine sulfate (369 people, 48.75%)
  2. Xanax (159 people, 21.00%)
  3. Neurontin (147 people, 19.42%)
  4. Oxycontin (146 people, 19.29%)
  5. Zometa (133 people, 17.57%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Morphine, Memory impairment

You can also:

On eHealthMe, Morphine (morphine sulfate) is often used for pain. Find out below the conditions Morphine is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Morphine used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (3 months ago):

  • want to find out of all my pain is a condition as well as my promary condition of back surgery and back pain


  • From this study (1 year ago):

  • burning mouth syndrome is a chronic pain condition of the tongue, mouth and soft palate affecting primarily women. I have been experiencing noticeable short term memory loss, especially of vocabulary. I am a professor, so this affects my life in a very immediate way -- both teaching and research/writing


    Jennifer Bauer on Dec, 16, 2012:

    My mom suffers from a slowly progressing Cerebellar Ataxia. She first had the shakes, then trouble walking, then walked w/ a walker, now walks w/ a walker & falls a lot. But her short term memory has suddenly failed. It has come on quite rapidly. They have never narrowed down what is behind the Cerebellar Ataxia, but she has been on epilepsy meds since age 9 & she is 62 now. So it is possible it came on as a side effect of any number of these meds. There is no cure & she will not get better.


    not on Dec, 31, 2012:

    Burning mouth syndrome is really the same as other vit deficinecie sof the mouth , may be attributable to digestive disease and rampant mouth flora which are bad, inavading the gut,, causing leaky gut, possible a result of pancreatitis....burning mouth syndriome is anew made up name for the same old syndrome...just like the wimpy new name aids for memory loss. A rather stupid label. Read up, that's what the internet is for...seems educated dr's are getting stupider....stupider than ever before....


  • From this study (2 years ago):

  • chelsea pioch on Jun, 7, 2012:

    19 F caucasian, african american, french, german. Accidental overdose of Morphine Sulfate 600mg never took morphine before. Side effects intense nausea, vomiting, hallucinations, dizziness, intense fatigue, confusion, lack of appetite, memory loss, amnesia (severe, loss of five years of life from 9:30am - 7:30 pm approx.) Continuous and intense headache (frontal lobe), abdominal pain/bowel pain, diahherea, tingling in extremities, loss of feeling in left foot, extreme weakness memory loss, headache, body pains, tingling in extremities loss of feeling in foot still present day 7. Only things that help with pain has been cannabis and fake cannabis (spice) doctors did no medical treatment when taken to er, just ran bloodwork and sent to speak to social worker.


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More reviews for: Morphine, Memory impairment

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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Related study

- Morphine side effects


Related symptom

- Memory Impairment



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