Review: could Neurontin cause Agitation?
Summary: Agitation could be caused by Neurontin, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Klonopin, and have Pain.
We study 56,199 people who have side effects while taking Neurontin from FDA and social media. Among them, 1,029 have Agitation. Find out below who they are, when they have Agitation and more.
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Neurontin (latest outcomes from 57,679 users) has active ingredients of gabapentin. It is often used in pain.
Agitation (state of anxiety or nervous excitement) (latest reports from 309,105 patients) has been reported by people with depression, quit smoking, pain, stress and anxiety, high blood pressure.
On Apr, 10, 2014: 56,222 people reported to have side effects when taking Neurontin. Among them, 1,033 people (1.84%) have Agitation. They amount to 0.33% of all the 308,623 people who have Agitation on eHealthMe.
Time on Neurontin when people have Agitation * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Gender of people who have Agitation when taking Neurontin * :
Age of people who have Agitation when taking Neurontin * :
Severity of Agitation when taking Neurontin ** :
|least||moderate||severe||most severe |
How people recovered from Agitation ** :
Top conditions involved for these people * :
- Pain (240 people, 23.23%)
- Depression (139 people, 13.46%)
- Neuropathy peripheral (95 people, 9.20%)
- Bipolar disorder (86 people, 8.33%)
- Anxiety (74 people, 7.16%)
Top co-used drugs for these people * :
- Klonopin (176 people, 17.04%)
- Seroquel (171 people, 16.55%)
- Ativan (150 people, 14.52%)
- Oxycontin (149 people, 14.42%)
- Xanax (149 people, 14.42%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Related topic: Neurontin, Agitation
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On eHealthMe, Neurontin (gabapentin) is often used for pain. Find out below the conditions Neurontin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
What is Neurontin used for and how effective is it:
Other drugs that are used to treat the same conditions:
Could it be a symptom from a condition:
Drugs in real world that are associated with:
Could your condition cause it?
Comments from related studies:
From this study (6 months ago):
I have been in pain and have suffered for over 7 years with muscle pain with cramping, aching, burning, stinging, pins/needles, weakness, numbness and paralysis, etc. I live with fatigue and utter exhaustion everyday and hate having to take medicine period, but have no choice in the matter. I know that this is something serious..I can feel it. I just have to get the Doctors, to find it...and fix whatever it is that is wrong.
I am trying to find what is the root cause of it all, then I might be able to find some relief.."Lord Willing". I have always been a driven individual and love life. I am a fighter and a survivor, so I will continue forward..until I find a way to the answer.
The pain level stays around 5 or 6 everyday and can be overwhelming at times, but I pray and I find relief for a moment..from The Lord. Grateful to be alive. Just want life to be normal again and to be able, to spend my time with my family that I have missed so much of.
From this study (13 months ago):
Kevin Peters Ph.d on Mar, 4, 2013:
Sammy, I'm a white 45 male; just wanted to agree on that Klonopin remark. When I was 21 I had my second kidney transplant which was a BAD issue all together, at any rate the hospital did not include my medications taken at home after my surgery. I went thru the worst hallucinations and jerking and seizures you could ever possibly imagine. This went on for almost 3 1/2 weeks before we decided to have me taken OUT of the hospital and relocated before they ended up taking my life. Then the whole staff of paychology including the chief of psychiatry cane in my room to see what they could do, Finallu. During one of my few moments of clarity the C.O.F after blaming me if talking "drugs" prior to my transplant listened to my word of telling him the meds I was on before being admitted. After asking when was the last time I had received my Klonopin and me not knowing, he then reviewed the charts, and didn't see me receiving this med once. He stormed out of the room of about 9 docs and came back in with two Klonopin; for the first time in almost 4 weeks and after three surgeries the first 72 hours I was hospitalized, I was sleeping like a baby, for about 49 hours with NO MORE hallucinations, or seizures or jerking! I finally got out of there without a kidney since that kidney was supposed to go to another man named the same as I in a different city! I do take Xanax and probably always will. The half life on Klonopin is much different hence one if its dangers, Nevwr Ever stop this drug cold! I've been on dialysis 25 1/2 years now and suffered from intense skin cancers, but have fought and done all I can do to live a normal as possible life, working full time except when I'm in yet another surgery, over 32 general anesthetic procedures since 1987. I was the youngest boy-man to ever be on the USA soccer team ready to play in the Korea 1988 Olympics. What a change in life.....
All the Best,
chris on Jun, 4, 2011:
i have been taking clonzepam and trazedone and my speech is a very hoarse voice, I am wondering if if my speech problem is from these drugs's side effects.
TwoDimes on Apr, 15, 2012:
Upon occasion, I, too, have become hoarse and from the use of Klonopin. I was VERY hoarse when I tried to cold turkey off of 4mgs of Klonopin. I am now down to 1.5mgs per day and, still, (as I said, upon occasion, I become hoarse. I am sure that the use of Klonopin is the causative factor. - TwoDimes -
SammySushi on Jul, 10, 2012:
Omigosh, never cold turkey clonopin, esp that high of a dose. My dad had a major seizure and hallucinations doing so.
Christophe on Nov, 13, 2012:
I suffer from Hypothyroidism, High Cholesterol & Cancer survivor because of Zyprexa use and previously being prescribed Carbamezapine causing Thyroid damage. My best advice to you if you don't want Hypothyroidism is have regular blood tests, Thyroid damage can be undetected for up to 5 years with no symptoms found on regular blood tests prematurally. Make sure you buy iodised salt to use on food when eating this will help reduce your risk of getting Hypothyroidism. two signs of Hypothyriodism which the Carbamezapine & Zyprexa medication boxes labels wont tell you is if your face becomes puffed up, red or sun sensitive while taking these medications this is a sign of Hypothyroidism. It wont be found on your blood test but later on it could appear out of the blue. The other sign to look for is baldness or hair loss on your head, this is another symptom. I hope these comments will help you. You have to weight up the benefits and negatives taking medications if you decide to take these medicines or not. It depends on how you cope with the drug side effects.
AUDREY on Dec, 16, 2012:
STARTED TAKING DILTIAZEM 60 MG AND I AM VERY CONSTIPATED. 70 YEARS OLD, HEART SURGERY A FAST HEART RATE....
Sonya on Feb, 24, 2013:
You definately need to take a stool softener...straining during defication can cause major problems in people with cardiac problems.
From this study (1 year ago):
MAL on Jul, 27, 2011:
I AM TAKING SUBOXONE PLUS RESPIRADOL ,THE SUBOXONE CAUSES ME TO BE EXTREMLY PARONOID, THIS IS MY THIRD ATTEMPT AT SUBOXONE, 1ST ONE I LASTED I WEEK AS I WAS VERY PARONOID, 2ND TRY LASTED 3 WEEKS BECAME PARONOID, WENT BACK TO TAKING PANADINE FORTE, EVENTUALLY GOT BACK ON SUBOXONE,BEEN ON IT FOR NEARLY SIX MONTHS, 24MG,EXTREMLY PARONOID,WHEN I GO OFF SUBOXONE PARANOIA STOPS, I ALSO WET MY BED EVERY NIGHT WHICH IS VERY TROUBLESOME,HAS ANYONE ELSE HAD SIMILAR PROBLEMS? IT IS LIKE I AM NOT ON MY RESPIRDOL AT ALL, WHICH I AM,
Donna L. on Dec, 3, 2011:
I wanted to let you know instead of suboxone they have VIVATROL NOW it's a once a month shot. the outcome looks great. I know person on it n she is doing very well.
scott on Sep, 5, 2012:
I have been on subs for 3 years, ive never taken more than 8 mg, thats after 4 years of being a junkie, no one needs 3 8mg pills, no one needs 2 8mg pills. After about a month i was down to 1, 2mg pill a day i have no cravings, it helps with my pain, i have no adverse side effects from 2mg a day. The only reason docs prescribe so much is profit, there is no money to made off of selling 30 1.75 pills. so they sell you 90 9.00 pills. Take my advice ween urself down to 4mg a day over 30 days, and i would be willing to bet your side effects go away
Jennifer on Oct, 11, 2012:
I have been Pain pill free for a year at the beginning of this month and have been taking 1 8MG suboxone sublingual film two times daily for the entire duration of my treatment (which is an actual outpatient program with meetings, therapists, drug tests,, groups, the whole 9) not just a trip to the doctor to score another pain med). Anywho, I was taking between 20-50 pain pills a day (a mix of Dilaudid, Vicodin, Roxycontin Ultrams and percocets) for about 4 years prior to beginning treatment before I decided enough was enough and that I needed help, especially since I am now only 24 almost 25 and have been taking pain meds for my back since I had 4 herniated discs at age 16, (and then a major spinal replacement surgery several years after due to spinal nerves being severed at a rate that would soon leave me paralyzed basically, hence the upheavel in my addiction). I have noticed from the beginning that I have had joint and ankle pain and it is now to the point that if I try to bend down, my knees just buckle bc it hurts that bad. I have never had a problem with my knees aching or throbbing in pain as they are now. My doctor insists that it "is certainly not from the suboxone" but I know she's just saying that out of fear that ill stop taking it an go running back to pain pills, which will never be a part of my life again though. I really think this pain is from the suboxone, what do you think? It's gotten so bad I have actual brushing on my knee caps. I've decided to get some feedback from other suboxone users and then going to my orthopedic surgeon to have him double check that there is no actual problem with my knees( one far far worse than the other). Any feedback would be appreciated. Thanks guys
Crystal on Oct, 19, 2012:
I am 28 yrs old female and i an also on suboxione,for 2 yrs now,plus cymbalta,buspar.i can say with experience of suboxione, ur dosage is a little much,for what it's worth,try to slowly decrease your mgs and see what makes you feel better,not so parinoid....good luck , : !
Brit on Oct, 24, 2012:
I agree with Scott 110%. I'm down to 2 mg twice daily, and I could really stand to cut out the second dose. The goal here is to let life be manageable again, and mine is; however, after about 2 years of being on suboxone, I've started to experience intense joint pain in my fingers and toes mainly. Also psoriasis. All signs point to psoriatic arthritis which is what I've diagnosed myself with. I'm just wondering how extreme this link is between arthritis and suboxone. You can read right on the suboxone website and swollen limbs are definitely a side effect. If anyone has any further info please let me know. Thanks and I wish everyone the best!!!
Jennifer on Oct, 24, 2012:
I too have had severe joint pain as swelling from an the 4th-6th month I was on suboxone up until now where it's very very severe. I had to go to the ER bc my feet and legs were so swollen when I woke up one morning I could not wear a single pair of shoes I own. They did an EKG and many other tests, only to tell me that basically suboxone may or may not be related to this and if the case is severe, it can be a mild form of an allergic reaction to either the dosage or the medication I general. But of course my psychiatrist told me it wasn't related at all and that it was probably just a combination of sitting all day and stress (maybe she thinks I'm a complete idiot, or she just assumes I will stop suboxone if I know the truth, who knows). I have such a high dosage bc of the amount of pain pills I was taking on a daily basis, exceeding a combo of 30-50 daily however now I think since it's been a year and a month since starting treatment, it's time to taper down. As you said, my goal was to see my life as manageable again without the medication.
Brit on Oct, 24, 2012:
Thats crazy & yes you're totally right about these doctors and pharmesuitical companies... They want our money and they want to keep us sick. I truly believe that. There are good doctors out there, but I keep finding more and more that natural is the way to go. The gov released a new study recently about vitamins and how we shouldn't take them bc there's no evidence that they work. Hahaha yeah I guess there wouldn't be evidence from a government study backed by drug companies. I'm proud of you for getting sober! I totally hear you! I started out taking 4 8mg tablets a day. It got me off opiates, but looking back I can't even understand how I functioned on all that suboxone. It's crazy! Now sometimes I get sick to my stomach just from taking my small dose. I too am tapering off, well trying to. I am finding a bit of challenge in it, but knowing how horrible these meds are for my body is helping my case. It's frustrating. I always encourage people to never start taking opiates bc they can't even imagine how horrible they really are. They ruin lives. Jen feel free to email me. I'd like to talk w you. My email is sincerelybrittanyboutique AT gmail dot com
Dj on Nov, 7, 2012:
Actually that's only partially true Scott. That's true if u never inject these nasty devils. I did subutex 8mg a day split into 2 mg doses for a long time. And when I quit the needle and tried to dose I needed 8 mg for every 2mg shot just to hold me. Unfortunately this happened after 70% of the top of my thick hair fell out. This drug is an endocrine and nervous system nightmare. It stores in your fat and takes a good 3 weeks just to get out of your system then the dreaded paws. My advice taper as slow as u possibly can. Or go back to shorter acting opiates for a month and bite that bullet. But never try and jump from a high sub dose as it may leave permanent lifelong damage like in my case.
Figster on Nov, 9, 2012:
Ok, Brit, let's get this straight; You are an opiod addict, converted to a long acting partial opiod agonist, weaning down on the medication. The study on vitamins wasn't a plot. In excess some cn be harmful. If you have success kicking opiod dependency using vitamins please let us know. You are sick, it's not doctors or companies wanting to maintain that condition. Are you doing better than before your subtext? Opiod dependency will likely need lifelong management, perhaps with suboxone; 4 mg per day is less than 4$; how much were you spending?
People get mad and start blaming the doctors and the Meds; Some will get off, go into decline and return to using. Hope that's not you, man.
Figster on Nov, 9, 2012:
Most physicians do not make money on dispensing medication but on the visit. The doctor who prescribed to you saved you with the Meds. You are down to 2 mg but saying "nobody" needs more than a specified amount is ludicrous. Average dose is roughly 12-16 mg in the beginning and most can wean down to 4 mg or even 2. Unless its a rare situation, your physician makes no more money having you on a higher dose. Good luck man, don't be hatin'
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