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Review: could Nexium cause Bone loss?

Summary: Bone loss is found among people who take Nexium, especially for people who are 60+ old, have been taking the drug for 5 - 10 years, also take medication Gabapentin, and have Gastrooesophageal reflux disease. We study 71,247 people who have side effects while taking Nexium from FDA and social media. Among them, 78 have Bone loss. Find out below who they are, when they have Bone loss and more.

You are not alone: join a support group for people who take Nexium and have Bone loss >>>

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Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. (latest outcomes from 73,208 Nexium users)

Bone loss

Bone loss has been reported by people with osteoporosis, osteopenia, high blood pressure, depression, high blood cholesterol. (latest reports from 2,076 Bone loss patients)

On May, 12, 2015: 71,247 people reported to have side effects when taking Nexium. Among them, 78 people (0.11%) have Bone Loss.

Trend of Bone loss in Nexium reports

Time on Nexium when people have Bone loss * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Bone loss0.00%0.00%0.00%10.00%10.00%50.00%30.00%

Age of people who have Bone loss when taking Nexium * :

Bone loss0.00%0.00%0.00%1.69%1.69%8.47%22.03%66.10%

Severity of Bone loss when taking Nexium ** :

leastmoderateseveremost severe
Bone loss0.00%100.00%0.00%0.00%

How people recovered from Bone loss ** :

while on the drugafter off the drugnot yet
Bone loss0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Gastrooesophageal reflux disease (19 people, 24.36%)
  2. Osteoporosis (19 people, 24.36%)
  3. Sleep disorder (15 people, 19.23%)
  4. Hypertension (12 people, 15.38%)
  5. Nausea (11 people, 14.10%)

Top co-used drugs for these people * :

  1. Gabapentin (39 people, 50.00%)
  2. Ambien (36 people, 46.15%)
  3. Zometa (35 people, 44.87%)
  4. Pepcid (33 people, 42.31%)
  5. Aredia (32 people, 41.03%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of nexium and bone loss on

Do you have Bone Loss while taking Nexium?


You are not alone! Join a support group on :
- support group for people who take Nexium and have Bone Loss
- support group for people who take Nexium
- support group for people who have Bone Loss

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More questions for: Nexium, Bone loss

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