Nexium and Osteonecrosis of jaw - from FDA reports


Summary

Osteonecrosis of jaw is found among people who take Nexium, especially for people who are female, 60+ old , have been taking the drug for 1 - 2 years, also take medication Zometa, and have Multiple myeloma . We study 114,868 people who have side effects while taking Nexium from FDA. Among them, 1,098 have Osteonecrosis of jaw. Find out below who they are, when they have Osteonecrosis of jaw and more.

What to expect?

If you take Nexium and have Osteonecrosis of jaw, find out what symptoms you could have in 1 year or longer.

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Nexium

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. (latest outcomes from Nexium 118,710 users)

Osteonecrosis Of Jaw

Osteonecrosis of jaw (death of bone of jaw) has been reported by people with osteoporosis, metastases to bone, multiple myeloma, breast cancer, osteopenia (latest reports from 22,457 Osteonecrosis of jaw patients).

On Feb, 11, 2017

114,868 people reported to have side effects when taking Nexium.
Among them, 1,098 people (0.96%) have Osteonecrosis Of Jaw


Number of reports submitted per year:

Could Nexium cause Osteonecrosis of jaw?

Time on Nexium when people have Osteonecrosis Of Jaw *:

  • < 1 month: 12.12 %
  • 1 - 6 months: 18.18 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 30.3 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 6.06 %

Gender of people who have Osteonecrosis Of Jaw when taking Nexium *:

  • female: 64.61 %
  • male: 35.39 %

Age of people who have Osteonecrosis Of Jaw when taking Nexium *:

  • 0-1: 0.0 %
  • 2-9: 0.12 %
  • 10-19: 0.35 %
  • 20-29: 1.27 %
  • 30-39: 2.66 %
  • 40-49: 10.52 %
  • 50-59: 30.06 %
  • 60+: 55.03 %

Top conditions involved for these people *:

  • Multiple Myeloma (239 people, 21.77%)
  • Metastases To Bone (206 people, 18.76%)
  • Breast Cancer (139 people, 12.66%)
  • Osteoporosis (132 people, 12.02%)
  • Pain (83 people, 7.56%)

Top co-used drugs for these people *:

  • Zometa (929 people, 84.61%)
  • Aredia (628 people, 57.19%)
  • Ambien (356 people, 32.42%)
  • Prednisone (325 people, 29.60%)
  • Neurontin (320 people, 29.14%)

Top other side effects for these people *:

  • Pain (868 people, 79.05%)
  • Stress And Anxiety (768 people, 69.95%)
  • Osteoarthritis (532 people, 48.45%)
  • Osteomyelitis (524 people, 47.72%)
  • Breathing Difficulty (523 people, 47.63%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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