Review: could Nexium cause Osteonecrosis Of Jaw?


Summary

Osteonecrosis of jaw is found among people who take Nexium, especially for people who are female, 60+ old , have been taking the drug for 1 - 2 years, also take medication Zometa, and have Multiple myeloma . We study 88,623 people who have side effects while taking Nexium from FDA and social media. Among them, 1,022 have Osteonecrosis of jaw. Find out below who they are, when they have Osteonecrosis of jaw and more.

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Nexium

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastrooesophageal reflux disease. (latest outcomes from Nexium 92,263 users)

Osteonecrosis Of Jaw

Osteonecrosis of jaw (death of bone of jaw) has been reported by people with tooth extraction, nausea and vomiting (latest reports from 17,063 Osteonecrosis of jaw patients).

On Aug, 29, 2016

88,623 people reported to have side effects when taking Nexium.
Among them, 1,022 people (1.15%) have Osteonecrosis Of Jaw


Number of reports submitted per year:

Could Nexium cause Osteonecrosis of jaw?

Time on Nexium when people have Osteonecrosis Of Jaw *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 4.35 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 47.83 %
  • 2 - 5 years: 43.48 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 4.35 %

Gender of people who have Osteonecrosis Of Jaw when taking Nexium *:

  • female: 65.1 %
  • male: 34.9 %

Age of people who have Osteonecrosis Of Jaw when taking Nexium *:

  • 0-1: 0.0 %
  • 2-9: 0.12 %
  • 10-19: 0.38 %
  • 20-29: 1.38 %
  • 30-39: 2.62 %
  • 40-49: 10.88 %
  • 50-59: 30.62 %
  • 60+: 54.0 %

Top conditions involved for these people *:

  • Multiple Myeloma (212 people)
  • Metastases To Bone (180 people)
  • Breast Cancer (138 people)
  • Osteoporosis (121 people)
  • Pain (78 people)

Top co-used drugs for these people *:

  • Zometa (898 people)
  • Aredia (610 people)
  • Ambien (352 people)
  • Prednisone (321 people)
  • Neurontin (314 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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