Review: could Nexium cause Osteonecrosis Of Jaw?


Summary

Osteonecrosis of jaw is found among people who take Nexium, especially for people who are female, 60+ old , have been taking the drug for 1 - 2 years, also take medication Zometa, and have Multiple myeloma . We study 109,161 people who have side effects while taking Nexium from FDA and social media. Among them, 1,075 have Osteonecrosis of jaw. Find out below who they are, when they have Osteonecrosis of jaw and more.

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Nexium

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastrooesophageal reflux disease. (latest outcomes from Nexium 115,436 users)

Osteonecrosis Of Jaw

Osteonecrosis of jaw (death of bone of jaw) has been reported by people with tooth extraction, nausea and vomiting (latest reports from 21,705 Osteonecrosis of jaw patients).

On Sep, 19, 2016

109,161 people reported to have side effects when taking Nexium.
Among them, 1,075 people (0.98%) have Osteonecrosis Of Jaw


Number of reports submitted per year:

Could Nexium cause Osteonecrosis of jaw?

Time on Nexium when people have Osteonecrosis Of Jaw *:

  • < 1 month: 6.45 %
  • 1 - 6 months: 19.35 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 35.48 %
  • 2 - 5 years: 32.26 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 6.45 %

Gender of people who have Osteonecrosis Of Jaw when taking Nexium *:

  • female: 64.41 %
  • male: 35.59 %

Age of people who have Osteonecrosis Of Jaw when taking Nexium *:

  • 0-1: 0.0 %
  • 2-9: 0.12 %
  • 10-19: 0.35 %
  • 20-29: 1.3 %
  • 30-39: 2.72 %
  • 40-49: 10.51 %
  • 50-59: 30.11 %
  • 60+: 54.9 %

Top conditions involved for these people *:

  • Multiple Myeloma (214 people, 19.91%)
  • Metastases To Bone (201 people, 18.70%)
  • Breast Cancer (138 people, 12.84%)
  • Osteoporosis (125 people, 11.63%)
  • Pain (83 people, 7.72%)

Top co-used drugs for these people *:

  • Zometa (923 people, 85.86%)
  • Aredia (624 people, 58.05%)
  • Ambien (356 people, 33.12%)
  • Prednisone (324 people, 30.14%)
  • Neurontin (319 people, 29.67%)

Top other side effects for these people *:

  • Pain (863 people, 80.28%)
  • Anxiety (751 people, 69.86%)
  • Osteoarthritis (529 people, 49.21%)
  • Dyspnoea (520 people, 48.37%)
  • Osteomyelitis (518 people, 48.19%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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