Could Niacin cause Rhabdomyolysis - from FDA reports


Summary

Rhabdomyolysis is found among people who take Niacin, especially for people who are male, 60+ old , have been taking the drug for 1 - 6 months, also take medication Simvastatin, and have High blood cholesterol . We study 6,828 people who have side effects while taking Niacin from FDA. Among them, 151 have Rhabdomyolysis. Find out below who they are, when they have Rhabdomyolysis and more.

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Niacin

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. (latest outcomes from Niacin 7,418 users)

Rhabdomyolysis

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down) has been reported by people with high blood cholesterol (latest reports from 40,305 Rhabdomyolysis patients).

On Nov, 22, 2016

6,828 people reported to have side effects when taking Niacin.
Among them, 151 people (2.21%) have Rhabdomyolysis


Number of reports submitted per year:

Could Niacin cause Rhabdomyolysis?

Time on Niacin when people have Rhabdomyolysis *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 66 %
  • 6 - 12 months: 12 %
  • 1 - 2 years: 8 %
  • 2 - 5 years: 10 %
  • 5 - 10 years: 2 %
  • 10+ years: 2 %

Gender of people who have Rhabdomyolysis when taking Niacin *:

  • female: 37.32 %
  • male: 62.68 %

Age of people who have Rhabdomyolysis when taking Niacin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.69 %
  • 40-49: 4.24 %
  • 50-59: 36.44 %
  • 60+: 57.63 %

Top conditions involved for these people *:

  • High Blood Cholesterol (42 people, 27.81%)
  • Hyperlipidaemia (24 people, 15.89%)
  • High Blood Pressure (4 people, 2.65%)
  • Quit Smoking (3 people, 1.99%)
  • Dyslipidaemia (3 people, 1.99%)

Top co-used drugs for these people *:

  • Simvastatin (44 people, 29.14%)
  • Zocor (33 people, 21.85%)
  • Baycol (31 people, 20.53%)
  • Bezafibrate (24 people, 15.89%)
  • Lasix (18 people, 11.92%)

Top other side effects for these people *:

  • Renal Failure Acute (42 people, 27.81%)
  • Weakness (37 people, 24.50%)
  • Muscle Aches (33 people, 21.85%)
  • Autoimmune Hepatitis (26 people, 17.22%)
  • Jaundice - Yellow Skin (19 people, 12.58%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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