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Review: could Norvasc cause Restless legs syndrome (Restless leg syndrome)?

Summary: Restless legs syndrome is found among people who take Norvasc, especially for people who are female, 60+ old, also take medication Lipitor, and have High blood pressure.

We study 79,026 people who have side effects while taking Norvasc from FDA and social media. Among them, 148 have Restless legs syndrome. Find out below who they are, when they have Restless legs syndrome and more.

You are not alone: join a support group for people who take Norvasc and have Restless legs syndrome >>>



Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from 80,505 Norvasc users)

Restless legs syndrome

Restless legs syndrome (a powerful urge to move your legs) has been reported by people with osteoporosis, depression, pain, high blood pressure, stress and anxiety. (latest reports from 17,498 Restless legs syndrome patients)

On Apr, 5, 2015: 79,022 people reported to have side effects when taking Norvasc. Among them, 148 people (0.19%) have Restless Legs Syndrome.

Trend of Restless legs syndrome in Norvasc reports

Time on Norvasc when people have Restless legs syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless legs syndrome10.00%20.00%0.00%20.00%10.00%0.00%40.00%

Gender of people who have Restless legs syndrome when taking Norvasc * :

Restless legs syndrome61.84%38.16%

Age of people who have Restless legs syndrome when taking Norvasc * :

Restless legs syndrome0.00%0.00%0.00%0.00%0.89%6.25%26.79%66.07%

Severity of Restless legs syndrome when taking Norvasc ** :


How people recovered from Restless legs syndrome ** :


Top conditions involved for these people * :

  1. Hypertension (22 people, 14.86%)
  2. Restless legs syndrome (17 people, 11.49%)
  3. Multiple myeloma (15 people, 10.14%)
  4. Arthritis (13 people, 8.78%)
  5. Osteoporosis (12 people, 8.11%)

Top co-used drugs for these people * :

  1. Lipitor (60 people, 40.54%)
  2. Aspirin (50 people, 33.78%)
  3. Neurontin (50 people, 33.78%)
  4. Prednisone (41 people, 27.70%)
  5. Lasix (39 people, 26.35%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of norvasc and restless legs syndrome on

Do you have Restless Legs Syndrome while taking Norvasc?




You are not alone! Join a support group on :
- support group for people who take Norvasc and have Restless Legs Syndrome
- support group for people who take Norvasc
- support group for people who have Restless Legs Syndrome

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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