Review: could Nystatin cause Enlarged spleen (Splenomegaly)?
Summary: Enlarged spleen is found among people who take Nystatin, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Lasix, and have Pain.
We study 8,916 people who have side effects while taking Nystatin from FDA and social media. Among them, 37 have Enlarged spleen. Find out below who they are, when they have Enlarged spleen and more.
You are not alone: join a mobile support group for people who take Nystatin and have Enlarged spleen >>>
Nystatin has active ingredients of nystatin. It is often used in thrush. (latest outcomes from Nystatin 9,095 users)
Enlarged spleen (enlargement of spleen) has been reported by people with rheumatoid arthritis, hiv infection, high blood pressure, hepatitis c, multiple sclerosis.(latest reports from Enlarged spleen 6,127 patients)
On Dec, 21, 2014: 8,916 people reported to have side effects when taking Nystatin. Among them, 37 people (0.41%) have Enlarged Spleen.
Time on Nystatin when people have Enlarged spleen * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Enlarged spleen||0.00%||0.00%||100.00%||0.00%||0.00%||0.00%||0.00% |
Age of people who have Enlarged spleen when taking Nystatin * :
|Enlarged spleen||0.00%||6.90%||10.34%||3.45%||10.34%||24.14%||3.45%||41.38% |
Severity of Enlarged spleen when taking Nystatin ** :
How people recovered from Enlarged spleen ** :
Top conditions involved for these people * :
- Pain (7 people, 18.92%)
- Multiple myeloma (6 people, 16.22%)
- Acute myeloid leukaemia (4 people, 10.81%)
- Acute lymphocytic leukaemia (3 people, 8.11%)
- Prophylaxis (2 people, 5.41%)
Top co-used drugs for these people * :
- Lasix (12 people, 32.43%)
- Potassium chloride (10 people, 27.03%)
- Ranitidine (9 people, 24.32%)
- Bactrim (9 people, 24.32%)
- Colace (8 people, 21.62%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Do you have Enlarged Spleen while taking Nystatin?
You are not alone! Join a mobile support group:
- support group for people who take Nystatin and have Enlarged Spleen
- support group for people who take Nystatin
- support group for people who have Enlarged Spleen
Drugs in real world that are associated with:
Could your condition cause:
Can you answer these questions (Ask a question):
- Can prolonged use of warfarin cause liver and spleen damage (1 answer)
I was on warfarin for ten years. they now found that I have cirrhosis of the liver my spleen is very enlarged can this all be caused by the prolonged use of the warfarin. Doctors giving me the run around but under my ribs is killing me and they just say take pain meds and go away
- I have been diagnosed with cll and now have very enlarged tonsils. my dr wants to put me on ofatumumab (arzerra) before having tonsils removed. have others had this treatment. and what is outcome?
I have been diagnosed with CLL - an intermediate form - meaning not too severe but not so mild either. After a rash (unknown cause) treated with prednisone, followed by a sore throat, my tonsils remained enlarged to the point where I have had some difficulty swallowing. A biopsy showed that the tonsils are expressing CLL, which means the enlargement is caused by CLL and not an infection. My hematologist recommends treatment with Ofatumumab (brand name arzerra) to shrink the tonsils and then I would have an ENT remove them. The hematologist thinks that just taking predisone for a longer period of time would not fully shrink them, or if it did work, I would likely get a recurrence, so recommends this mild CLL treatment. Have others had a similar situation, and if so, what drugs were used to shrink the tonsils? Thanks in advance.
- Does clonazepam 0.5 daily cause low white blood count?
do these drugs cause high blood pressure or low wbc, low platelets, enlarged spleen, skipped heartbeats, lightheadedness, unexplained bruises?
- Causes of enlarged spleen?
22 yo pt. History positive for diverticulosus with one bout of diverticulitis, svt and slight arrhythmia, IBS, peptic ulcers, bipolar disorder type 2, and morbid obesity.
Pt. Had a scan done at the end of May to r/o diverticulitis. Scan revealed splenomegaly.
Pt. Complains of fatigue, loss of appetite, low grade fevers(with no obvious causes), and states that she has seen an increase of moles on her skin.
What should pt. Be concerned about/speak with her internist about? Any ideas?
More questions for: Nystatin, Enlarged spleen
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Comments from related studies:
From this study (1 month ago):
was in ICU on ventalator for 14 dyas , moved to regular room for 7 days not getting any better mentally
From this study (2 months ago):
Upon reduction of jakafi dose due to low platelet count from 20 mg to 5 mg every 12 hours patient experienced extreme pain experienced low blood pressure and rapid heartbeat and with admission to emergency was treated for shock and then diagnosed with toxic shock syndrome and treated for that. The blood and urine tests however showed ant reason for infection after 5 days. He died 40 hours after reaching the hospital. Cytokine overreaction is my belief that brought on a septic shock like syndrome.
Dave M. on Oct, 12, 2014:
Maybe patient should not have been on 20mg. Something else likely going on here with sudden reduction from 20mg to 5mg. Sudden reduction due to sudden drop in platelets. Slower dose reduction with transfusion if required would be in order.
Ann Chris on Oct, 14, 2014:
I agree. This took place 16 months ago and was done as directed by the drug rep. Since that time much more has been made known about dosage. The patient was also started on the high dose where research shows now the dose should be started low and slowly worked up. My theory is the rapid decrease in the drug caused a cytokine reaction causing system shock.
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