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Review: could Nystatin cause Enlarged spleen (Splenomegaly)?

We study 8,915 people who have side effects while taking Nystatin from FDA and social media. Among them, 37 have Enlarged spleen. Find out below who they are, when they have Enlarged spleen and more.

Get connected: join a mobile support group for people who take Nystatin and have Enlarged spleen >>>

Nystatin

Nystatin (latest outcomes from 9,094 users) has active ingredients of nystatin. It is often used in thrush.

Enlarged spleen

Enlarged spleen (enlargement of spleen) (latest reports from 39,323 patients) has been reported by people with rheumatoid arthritis, hiv infection, high blood pressure, hepatitis c, multiple sclerosis.

On Oct, 25, 2014: 8,915 people reported to have side effects when taking Nystatin. Among them, 37 people (0.42%) have Enlarged Spleen.

Trend of Enlarged spleen in Nystatin reports

Time on Nystatin when people have Enlarged spleen * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Enlarged spleen0.00%0.00%100.00%0.00%0.00%0.00%0.00%

Age of people who have Enlarged spleen when taking Nystatin * :

0-12-910-1920-2930-3940-4950-5960+
Enlarged spleen0.00%6.90%10.34%3.45%10.34%24.14%3.45%41.38%

Severity of Enlarged spleen when taking Nystatin ** :

n/a

How people recovered from Enlarged spleen ** :

n/a

Top conditions involved for these people * :

  1. Pain (7 people, 18.92%)
  2. Multiple myeloma (6 people, 16.22%)
  3. Acute myeloid leukaemia (4 people, 10.81%)
  4. Acute lymphocytic leukaemia (3 people, 8.11%)
  5. Prophylaxis (2 people, 5.41%)

Top co-used drugs for these people * :

  1. Lasix (12 people, 32.43%)
  2. Potassium chloride (10 people, 27.03%)
  3. Ranitidine (9 people, 24.32%)
  4. Bactrim (9 people, 24.32%)
  5. Colace (8 people, 21.62%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Enlarged Spleen while taking Nystatin?

Get connected! Join a mobile support group:
- support group for people who take Nystatin and have Enlarged Spleen
- support group for people who take Nystatin
- support group for people who have Enlarged Spleen

Comments from related studies:

  • From this study (2 weeks ago):

  • Upon reduction of jakafi dose due to low platelet count from 20 mg to 5 mg every 12 hours patient experienced extreme pain experienced low blood pressure and rapid heartbeat and with admission to emergency was treated for shock and then diagnosed with toxic shock syndrome and treated for that. The blood and urine tests however showed ant reason for infection after 5 days. He died 40 hours after reaching the hospital. Cytokine overreaction is my belief that brought on a septic shock like syndrome.

    Reply

    Ann Chris on Oct, 14, 2014:

    I agree. This took place 16 months ago and was done as directed by the drug rep. Since that time much more has been made known about dosage. The patient was also started on the high dose where research shows now the dose should be started low and slowly worked up. My theory is the rapid decrease in the drug caused a cytokine reaction causing system shock.

    Reply

    Dave M. on Oct, 12, 2014:

    Maybe patient should not have been on 20mg. Something else likely going on here with sudden reduction from 20mg to 5mg. Sudden reduction due to sudden drop in platelets. Slower dose reduction with transfusion if required would be in order.

    Reply

  • From this study (4 weeks ago):

  • I have pos. speckled ANA titer since I was in my early 20's, but no autoimmunity symptoms or rashes to report. My LLMD has dx'd me as having lyme disease and I am in treatment for that currently.

    Reply

  • From this study (1 month ago):

  • My jaw pops when I chew on the left side only. It hurts if I open it more than an inch. I have hold my head back in order to put food in mouth because I can only open it so wide.

    Reply

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On eHealthMe, Nystatin (nystatin) is often used for thrush. Find out below the conditions Nystatin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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