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Review: could Omeprazole cause Type 2 diabetes mellitus (Type 2 diabetes)?

Summary: Type 2 diabetes mellitus is found among people who take Omeprazole, especially for people who are female, 60+ old, also take medication Seroquel, and have Depression.

We study 89,994 people who have side effects while taking Omeprazole from FDA and social media. Among them, 250 have Type 2 diabetes mellitus. Find out below who they are, when they have Type 2 diabetes mellitus and more.

You are not alone: join a support group for people who take Omeprazole and have Type 2 diabetes mellitus >>>



Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. (latest outcomes from 92,893 Omeprazole users)

Type 2 diabetes mellitus

Type 2 diabetes mellitus has been reported by people with depression, bipolar disorder, stress and anxiety, schizophrenia, sleep disorder. (latest reports from 92,887 Type 2 diabetes mellitus patients)

On Mar, 26, 2015: 89,969 people reported to have side effects when taking Omeprazole. Among them, 250 people (0.28%) have Type 2 Diabetes Mellitus.

Trend of Type 2 diabetes mellitus in Omeprazole reports

Time on Omeprazole when people have Type 2 diabetes mellitus * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Type 2 diabetes mellitus0.00%0.00%0.00%0.00%50.00%0.00%50.00%

Gender of people who have Type 2 diabetes mellitus when taking Omeprazole * :

Type 2 diabetes mellitus54.68%45.32%

Age of people who have Type 2 diabetes mellitus when taking Omeprazole * :

Type 2 diabetes mellitus0.00%0.00%0.43%0.00%7.73%30.04%27.47%34.33%

Severity of Type 2 diabetes mellitus when taking Omeprazole ** :

leastmoderateseveremost severe
Type 2 diabetes mellitus0.00%50.00%0.00%50.00%

How people recovered from Type 2 diabetes mellitus ** :

while on the drugafter off the drugnot yet
Type 2 diabetes mellitus0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Depression (70 people, 28.00%)
  2. Anxiety (40 people, 16.00%)
  3. Sleep disorder (38 people, 15.20%)
  4. Gastrooesophageal reflux disease (36 people, 14.40%)
  5. Bipolar disorder (25 people, 10.00%)

Top co-used drugs for these people * :

  1. Seroquel (91 people, 36.40%)
  2. Aspirin (62 people, 24.80%)
  3. Simvastatin (61 people, 24.40%)
  4. Lisinopril (58 people, 23.20%)
  5. Clonazepam (50 people, 20.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

srikanth raghavachari (1 year ago):

I was never diabetic and My Blood glucose fasting never touched even 100 before 4 months although i take medicine for hypertension. My GP prescribed Omaperazole 20mg for my acidity problem and i have been taking for 2 months , slowly my urinary input increased and i just went for fasting blood sugar i was shocked to see my fasting blood sugar shot to 150. I searched the net once i was convinced that omaperazole may be the culprit i have taken this medicine off from today. I see no major research into this area and GP are prescribing this drug indiscriminately . I want to know any research on this area. Pl share
Reply the comment

Born again (1 year ago):

Just like you, I´m sure as well. Some days after I stopped taking Omeprazol my blood glucose levels went back to normal levels. After one month I started with Omeprazol again and my bg level went up again. Now I`ve been without Omeprazol for about 4 months and my bg level is perfect. I eat, drink and live the same way I did when I was diagnosed with type 2 diabetes in 2004.
Reply the comment

mikl (3 years ago):

I'm fairly convinced tha tOmeprazole increases blood glucose levels. Since I stopped taking it my BG is so much better. What should I do about notifying people who can do some research into this. Obviously the manufacturer won't want to admit to anything.
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How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Type 2 Diabetes Mellitus while taking Omeprazole?




You are not alone! Join a support group on :
- support group for people who take Omeprazole and have Type 2 Diabetes Mellitus
- support group for people who take Omeprazole
- support group for people who have Type 2 Diabetes Mellitus

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