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Review: could Oxycodone cause Pancreatitis?

Summary: Pancreatitis could be caused by Oxycodone, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Oxycodone hcl, and have Pain.

We study 25,880 people who have side effects while taking Oxycodone from FDA and social media. Among them, 162 have Pancreatitis. Find out below who they are, when they have Pancreatitis and more.

On Apr, 8, 2014: 25,880 people reported to have side effects when taking Oxycodone. Among them, 162 people (0.63%) have Pancreatitis. They amount to 0.08% of all the 196,071 people who have Pancreatitis on eHealthMe.

Trend of Pancreatitis in Oxycodone reports

Time on Oxycodone when people have Pancreatitis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Pancreatitis when taking Oxycodone * :


Age of people who have Pancreatitis when taking Oxycodone * :


Severity of Pancreatitis when taking Oxycodone ** :

leastmoderateseveremost severe

How people recovered from Pancreatitis ** :

while on the drugafter off the drugnot yet

Top conditions involved for these people * :

  1. Pain (37 people, 22.84%)
  2. Depression (14 people, 8.64%)
  3. Contraception (12 people, 7.41%)
  4. Insomnia (10 people, 6.17%)
  5. Rheumatoid arthritis (10 people, 6.17%)

Top co-used drugs for these people * :

  1. Oxycodone hcl (162 people, 100.00%)
  2. Aspirin (31 people, 19.14%)
  3. Promethazine (28 people, 17.28%)
  4. Lisinopril (27 people, 16.67%)
  5. Omeprazole (26 people, 16.05%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Oxycodone, Pancreatitis

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On eHealthMe, Oxycodone (oxycodone hydrochloride) is often used for pain. Find out below the conditions Oxycodone is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Oxycodone used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 years ago):

  • Paul Minard on Jun, 18, 2012:

    Scottish descent Male, 55; quit cold turkey from oxycontin (50mg 2X day for arthritis hips & lower spine) for what I thought was a constipation-related cramp. A week later, after withdrawal, another one happened & I called the ambulance, the pain was so bad. Emergency at first thought the same thing but the doctor in the morning said it was pancreatitis, caused by the oxycontin, as I had also quit drinking nearly two years before. I.v. liquids for a day with ALL drugs stopped; clear liquid diet the next. My numbers went down, the liver numbers climbed for a bit, but probably because I was being allowed 3 percocets a day. They stayed steady long enough to try a boiled turkey sandwich, which I did without pain & I was allowed to go home...
    I've been on the Glycemic Index diet for 5 months & lost close to 60 lbs. I still smoke, about 10 cigarettes a day. I had been planning to quit when I hit my good BMI, but fate loves to change the rules of the game on ya...Slowly getting back on the diet which is already low fat & trying to be careful.I don't have to worry about losing time from the diet - I dropped five pounds in three days at the hospital... Taking a Sennokot stool softener & 3-4 litres of water against the Percocet. And keeping my fingers crossed...


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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