Review: could Paxil cause Mania?


Summary

Mania is found among people who take Paxil, especially for people who are female, 40-49 old , have been taking the drug for 1 - 6 months, also take medication Depakote, and have Depression . We study 71,194 people who have side effects while taking Paxil from FDA and social media. Among them, 648 have Mania. Find out below who they are, when they have Mania and more.

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Paxil

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. (latest outcomes from Paxil 78,934 users)

Mania

Mania (a state of abnormally elevated or irritable mood) has been reported by people with fever, drug ineffective, confusional state, drowsiness, insomnia (latest reports from 14,247 Mania patients).

On Sep, 16, 2016

71,194 people reported to have side effects when taking Paxil.
Among them, 648 people (0.91%) have Mania


Number of reports submitted per year:

Could Paxil cause Mania?

Time on Paxil when people have Mania *:

  • < 1 month: 18.02 %
  • 1 - 6 months: 33.78 %
  • 6 - 12 months: 13.06 %
  • 1 - 2 years: 18.02 %
  • 2 - 5 years: 9.46 %
  • 5 - 10 years: 7.21 %
  • 10+ years: 0.45 %

Gender of people who have Mania when taking Paxil *:

  • female: 52.3 %
  • male: 47.7 %

Age of people who have Mania when taking Paxil *:

  • 0-1: 0.0 %
  • 2-9: 1.03 %
  • 10-19: 12.16 %
  • 20-29: 16.08 %
  • 30-39: 17.73 %
  • 40-49: 20.41 %
  • 50-59: 17.73 %
  • 60+: 14.85 %

Severity if Mania when taking Paxil **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

How people recovered from Mania **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Depression (197 people, 30.40%)
  • Bipolar Disorder (56 people, 8.64%)
  • Anxiety (46 people, 7.10%)
  • Insomnia (28 people, 4.32%)
  • Panic Disorder (20 people, 3.09%)

Top co-used drugs for these people *:

  • Depakote (77 people, 11.88%)
  • Seroquel (48 people, 7.41%)
  • Zyprexa (44 people, 6.79%)
  • Klonopin (36 people, 5.56%)
  • Prozac (34 people, 5.25%)

Top other side effects for these people *:

  • Insomnia (149 people, 22.99%)
  • Anxiety (135 people, 20.83%)
  • Aggression (131 people, 20.22%)
  • Suicidal Ideation (113 people, 17.44%)
  • Depression (110 people, 16.98%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Mania when taking Paxil?

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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