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Review: could Phentermine cause Migraine?

Summary: Migraine could be caused by Phentermine, especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months, also take Pondimin, and have Insomnia.

We study 10,844 people who have side effects while taking Phentermine from FDA and social media. Among them, 8 have Migraine. Find out below who they are, when they have Migraine and more.

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Phentermine

Phentermine (latest outcomes from 12,860 users) has active ingredients of phentermine hydrochloride. It is often used in obesity, lipids abnormal. Commonly reported side effects of Phentermine include valvular heart disease, heart disease, chest pain, chest pain aggravated, cardiac disorder.

Migraine

Migraine (headache) (latest reports from 170,139 patients) has been reported by people with multiple sclerosis, birth control, depression, osteoporosis, pain.

On Apr, 7, 2014: 10,702 people reported to have side effects when taking Phentermine. Among them, 62 people (0.58%) have Migraine. They amount to 0.04% of all the 169,369 people who have Migraine on eHealthMe.

Trend of Migraine in Phentermine reports

Time on Phentermine when people have Migraine * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Migraine14.29%28.57%14.29%14.29%14.29%14.29%0.00%

Gender of people who have Migraine when taking Phentermine * :

FemaleMale
Migraine98.39%1.61%

Age of people who have Migraine when taking Phentermine * :

0-12-910-1920-2930-3940-4950-5960+
Migraine0.00%0.00%2.38%7.14%28.57%38.10%19.05%4.76%

Severity of Migraine when taking Phentermine ** :

leastmoderateseveremost severe
Migraine0.00%33.33%66.67%0.00%

How people recovered from Migraine ** :

while on the drugafter off the drugnot yet
Migraine0.00%50.00%50.00%

Top conditions involved for these people * :

  1. Insomnia (2 people, 3.23%)
  2. Tooth abscess (2 people, 3.23%)
  3. Weight loss (2 people, 3.23%)
  4. Obesity (2 people, 3.23%)
  5. Post-traumatic stress disorder (2 people, 3.23%)

Top co-used drugs for these people * :

  1. Pondimin (53 people, 85.48%)
  2. Redux (22 people, 35.48%)
  3. Fastin (14 people, 22.58%)
  4. Paxil (8 people, 12.90%)
  5. Phentermine hydrochloride (6 people, 9.68%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

Lifetime Migraine Lady (1 year ago):

How horrible! You might consider a switch to Topomax, similar weight control with migraine meds if your neurologist likes the drug for you. I think this is like so many drugs (Botox for migraines, epilepsy medicine, heart meds...) works like magic for some and hurts others. At least you know quickly and the ill effects wear off after a few days so you can try something else until you find the perfect thing. Only took me 30 years of trying...
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Ms. MajorMigraine (1 year ago):

That's interesting that your PCP perscribed it for your migraines. I was perscribed Phentermine for weight loss as my BMI is over 30. I have taken it for approx. five months now, and get migraines MORE frequently (I've had diagnosed migraines for about 20 years now). In fact, the only time I DON'T get a migraine is after I have stopped taking it for three days in a row and I can flush the Phentermine completely from my body...
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Lifetime Migraine Lady (2 years ago):

There are several forums I have visited where the posters and bloggers have been trumpeting the positive effects of phentermine on migraine. I have suffered from migraine since the early 1980s (I am in my 30 now). When my PCP tried phentermine for me for short term weight loss I was shocked to notice my migraines went from on average every other day to maybe 5 a month. I stayed on for a year and it was the single best migraine year of my life. My neurologist is considering putting me on this drug to control my migraines. When I looked to see if others were doing the same, the web is full of these references. As with every drug that helps some migraine patients, it hurts some others. If you have migraines, don't back from trying phentermine - could have result like we have and isn't it worth the possibility of a few extra headaches to have a shot at reducing frequency by 1/4?
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How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Phentermine, Migraine

You can also:

On eHealthMe, Phentermine (phentermine hydrochloride) is often used for obesity. Find out below the conditions Phentermine is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Phentermine used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (3 days ago):

  • Should I take electrolyte supplements?

    Reply

  • From this study (3 days ago):

  • started taking this drug in Dec 2011 for weight loss for 24 days and during that time developed pulsatile tinnitus which has continued 24/7 for the last 27 months - have seen ENTs, neurologists, gp, chiropractor, acupuncturist to try to cure the condition. I've had MRIs and MRAs of the head and brain, carotid artery as well as a lumbar puncture to see if it might be a build up on spinal fluid - all tests came back with good results. Is phentermine hydrochloride the cause of my pulsatile tinnitus? is there a medication that can reverse the symtoms?

    Reply

  • From this study (3 days ago):

  • after taking phentermine hydrochloride 37.5 mg tablets for less than one month, pulsatile tinnitus started and has continued for 26 months - would this drug have caused this as I have done every test including a lumbar puncture and have seen ENTs, dentists and neurologists. I am desperate to find if this drug started the pulsatile tinnitus and if there is any drug to reverse it?

    Reply

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